FR2213059A1 - - Google Patents

Info

Publication number
FR2213059A1
FR2213059A1 FR7400055A FR7400055A FR2213059A1 FR 2213059 A1 FR2213059 A1 FR 2213059A1 FR 7400055 A FR7400055 A FR 7400055A FR 7400055 A FR7400055 A FR 7400055A FR 2213059 A1 FR2213059 A1 FR 2213059A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7400055A
Other versions
FR2213059B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of FR2213059A1 publication Critical patent/FR2213059A1/fr
Application granted granted Critical
Publication of FR2213059B1 publication Critical patent/FR2213059B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7400055A 1973-01-04 1974-01-02 Expired FR2213059B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32105873A 1973-01-04 1973-01-04
US417702A US3910930A (en) 1973-01-04 1973-11-20 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones

Publications (2)

Publication Number Publication Date
FR2213059A1 true FR2213059A1 (fr) 1974-08-02
FR2213059B1 FR2213059B1 (fr) 1977-09-09

Family

ID=26982795

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7400055A Expired FR2213059B1 (fr) 1973-01-04 1974-01-02

Country Status (8)

Country Link
US (1) US3910930A (fr)
JP (1) JPS4995980A (fr)
AU (1) AU6418474A (fr)
BE (1) BE809410A (fr)
DE (1) DE2400094A1 (fr)
FR (1) FR2213059B1 (fr)
IL (1) IL43955A0 (fr)
NL (1) NL7400132A (fr)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008259A1 (fr) * 1978-07-20 1980-02-20 SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE Nouveaux dérivés de la pipéridylbenzimidazolinone, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
US4224333A (en) * 1978-03-22 1980-09-23 Roussel Uclaf Antihypertensive 2H-indol-2-ones
EP0030174A1 (fr) * 1979-11-15 1981-06-10 SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE Nouveaux dérivés de la pipéridylbenzimidazolinone, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
EP0035374A2 (fr) * 1980-03-01 1981-09-09 JOHN WYETH & BROTHER LIMITED Dérivés de la pipéridyl-urée, -thiourée et -guanidine, leurs intermédiaires, procédés pour leur préparation et compositions pharmaceutiques les contenant
FR2482101A1 (fr) * 1980-05-07 1981-11-13 Cerm Cent Europ Rech Mauvernay 2-methanol a-aminomethyl benzo (1,4) dioxines, leur procede de preparation et leur application en therapeutique
EP0068261A1 (fr) * 1981-06-20 1983-01-05 Hoechst Aktiengesellschaft Dérivés de N-oxacyclyl-alkylpipéridine, leur préparation, produits pharmaceutiques qui les contiennent et leur emploi
WO1984000546A1 (fr) * 1982-07-26 1984-02-16 Bouchara Emile Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
EP0367888A1 (fr) * 1988-11-08 1990-05-16 ISTITUTO LUSO FARMACO D'ITALIA S.p.A. Dérivés de 1,4-benzodioxine 2,2-disubstitués ayant une action hypotensive

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996362A (en) * 1975-05-28 1976-12-07 E. R. Squibb & Sons, Inc. 2-[[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-(piperidinyl or 1,2,3,6-tetrahydro-1-pyridinyl)]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones
GB1582239A (en) * 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
GR71865B (fr) * 1978-03-20 1983-07-07 Ciba Geigy
US4181802A (en) * 1978-05-11 1980-01-01 Janssen Pharmaceutica N.V. 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones
JPS54160371A (en) * 1978-06-02 1979-12-19 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agents comprising it
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
JPS5668680A (en) * 1979-11-06 1981-06-09 Kyowa Hakko Kogyo Co Ltd Novel piperidine derivative and hypotensive agent containing the same
EP0300077B1 (fr) * 1987-07-23 1993-03-17 Mitsubishi Denki Kabushiki Kaisha Détecteur de surcharge
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
HUP0201404A3 (en) 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
DE60014896T2 (de) 1999-06-02 2006-02-02 Janssen Pharmaceutica N.V. Pyrrolidinyl, piperidinyl oder homopiperidinyl substituierte (benzodioxan, benzofuran oder benzopyran) derivate
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
CA2465328C (fr) * 2001-11-01 2011-06-14 Michael Francis Gross Piperidines
US8354434B2 (en) * 2006-01-30 2013-01-15 Purdue Pharma L.P. Cyclourea compounds as calcium channel blockers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633495A (fr) * 1962-06-13
US3238216A (en) * 1963-06-20 1966-03-01 Res Lab Dr C Janssen N V Substituted 1, 3, 8-triaza-spiro (4, 5) decanes
US3345364A (en) * 1964-05-06 1967-10-03 Janssen Pharmaceutica Nv Benzimidazolinyl piperidines
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
JPS4920788B1 (fr) * 1970-08-19 1974-05-27

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224333A (en) * 1978-03-22 1980-09-23 Roussel Uclaf Antihypertensive 2H-indol-2-ones
EP0008259A1 (fr) * 1978-07-20 1980-02-20 SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE Nouveaux dérivés de la pipéridylbenzimidazolinone, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
EP0030174A1 (fr) * 1979-11-15 1981-06-10 SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE Nouveaux dérivés de la pipéridylbenzimidazolinone, leurs procédés de préparation et les compositions pharmaceutiques les renfermant
EP0035374A2 (fr) * 1980-03-01 1981-09-09 JOHN WYETH & BROTHER LIMITED Dérivés de la pipéridyl-urée, -thiourée et -guanidine, leurs intermédiaires, procédés pour leur préparation et compositions pharmaceutiques les contenant
EP0035374A3 (en) * 1980-03-01 1981-11-11 John Wyeth & Brother Limited Piperidyl - urea, - thiourea and - guanidine derivatives, and intermediates therefor, processes for preparing them and pharmaceutical compositions containing the derivatives
FR2482101A1 (fr) * 1980-05-07 1981-11-13 Cerm Cent Europ Rech Mauvernay 2-methanol a-aminomethyl benzo (1,4) dioxines, leur procede de preparation et leur application en therapeutique
EP0068261A1 (fr) * 1981-06-20 1983-01-05 Hoechst Aktiengesellschaft Dérivés de N-oxacyclyl-alkylpipéridine, leur préparation, produits pharmaceutiques qui les contiennent et leur emploi
US4470989A (en) * 1981-06-20 1984-09-11 Hoechst Aktiengesellschaft Neuroleptic n-oxacyclyl-alkylpiperidine derivatives
WO1984000546A1 (fr) * 1982-07-26 1984-02-16 Bouchara Emile Nouveaux derives substitues du 2,5-diamino 1,4-diazole, leurs procedes de preparation et les compositions pharmaceutiques en renfermant
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
EP0367888A1 (fr) * 1988-11-08 1990-05-16 ISTITUTO LUSO FARMACO D'ITALIA S.p.A. Dérivés de 1,4-benzodioxine 2,2-disubstitués ayant une action hypotensive

Also Published As

Publication number Publication date
IL43955A0 (en) 1974-05-16
FR2213059B1 (fr) 1977-09-09
BE809410A (nl) 1974-07-04
JPS4995980A (fr) 1974-09-11
US3910930A (en) 1975-10-07
AU6418474A (en) 1975-07-10
DE2400094A1 (de) 1974-07-18
NL7400132A (fr) 1974-07-08

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Legal Events

Date Code Title Description
ST Notification of lapse