IL43456A - 1,2,3,4,5,6-hexahydro-8-hydroxy-3-benzazocine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1,2,3,4,5,6-hexahydro-8-hydroxy-3-benzazocine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL43456A
IL43456A IL43456A IL4345673A IL43456A IL 43456 A IL43456 A IL 43456A IL 43456 A IL43456 A IL 43456A IL 4345673 A IL4345673 A IL 4345673A IL 43456 A IL43456 A IL 43456A
Authority
IL
Israel
Prior art keywords
acid addition
methyl
compound
formula
addition salt
Prior art date
Application number
IL43456A
Other languages
English (en)
Other versions
IL43456A0 (en
Original Assignee
Sparamedica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sparamedica Ag filed Critical Sparamedica Ag
Publication of IL43456A0 publication Critical patent/IL43456A0/xx
Publication of IL43456A publication Critical patent/IL43456A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
IL43456A 1972-10-24 1973-10-22 1,2,3,4,5,6-hexahydro-8-hydroxy-3-benzazocine derivatives,their preparation and pharmaceutical compositions containing them IL43456A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30004472A 1972-10-24 1972-10-24
US34880873A 1973-04-06 1973-04-06
US38321673A 1973-07-27 1973-07-27

Publications (2)

Publication Number Publication Date
IL43456A0 IL43456A0 (en) 1974-01-14
IL43456A true IL43456A (en) 1976-12-31

Family

ID=27404688

Family Applications (1)

Application Number Title Priority Date Filing Date
IL43456A IL43456A (en) 1972-10-24 1973-10-22 1,2,3,4,5,6-hexahydro-8-hydroxy-3-benzazocine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
JP (1) JPS4972280A (de)
AR (2) AR200581A1 (de)
AU (1) AU6124373A (de)
DD (1) DD109629A5 (de)
DE (1) DE2353062A1 (de)
ES (1) ES419855A1 (de)
FR (1) FR2203637B1 (de)
GB (1) GB1448243A (de)
IE (1) IE38399B1 (de)
IL (1) IL43456A (de)
LU (1) LU68663A1 (de)
NL (1) NL7314606A (de)
PH (1) PH11587A (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH529763A (de) * 1968-02-09 1972-10-31 Takeda Chemical Industries Ltd Verfahren zur Herstellung neuer Hexahydrobenzazocine

Also Published As

Publication number Publication date
GB1448243A (en) 1976-09-02
FR2203637B1 (de) 1977-01-28
AU6124373A (en) 1975-04-10
LU68663A1 (de) 1975-06-24
IE38399L (en) 1974-04-24
DD109629A5 (de) 1974-11-12
DE2353062A1 (de) 1974-05-09
IE38399B1 (en) 1978-03-01
JPS4972280A (de) 1974-07-12
FR2203637A1 (de) 1974-05-17
AR200581A1 (es) 1974-11-22
NL7314606A (de) 1974-04-26
IL43456A0 (en) 1974-01-14
AR207853A1 (es) 1976-11-08
ES419855A1 (es) 1976-02-16
PH11587A (en) 1978-03-31

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