IL42458A - 1,4-dihydropyridines their production and pharmaceutical compositions containing them - Google Patents

1,4-dihydropyridines their production and pharmaceutical compositions containing them

Info

Publication number
IL42458A
IL42458A IL7342458A IL4245873A IL42458A IL 42458 A IL42458 A IL 42458A IL 7342458 A IL7342458 A IL 7342458A IL 4245873 A IL4245873 A IL 4245873A IL 42458 A IL42458 A IL 42458A
Authority
IL
Israel
Prior art keywords
general formula
compound
ester
reacted
compounds according
Prior art date
Application number
IL7342458A
Other languages
English (en)
Other versions
IL42458A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL42458A0 publication Critical patent/IL42458A0/xx
Publication of IL42458A publication Critical patent/IL42458A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL7342458A 1972-06-10 1973-06-07 1,4-dihydropyridines their production and pharmaceutical compositions containing them IL42458A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2228363A DE2228363A1 (de) 1972-06-10 1972-06-10 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
IL42458A0 IL42458A0 (en) 1973-08-29
IL42458A true IL42458A (en) 1977-07-31

Family

ID=5847399

Family Applications (1)

Application Number Title Priority Date Filing Date
IL7342458A IL42458A (en) 1972-06-10 1973-06-07 1,4-dihydropyridines their production and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US3923818A (de)
JP (1) JPS4948680A (de)
AT (2) AT328447B (de)
AU (1) AU473996B2 (de)
BE (1) BE800679A (de)
CA (1) CA999592A (de)
CH (7) CH591444A5 (de)
CS (5) CS178888B2 (de)
DD (1) DD109383A5 (de)
DE (1) DE2228363A1 (de)
ES (5) ES415749A1 (de)
FR (1) FR2187347B1 (de)
GB (1) GB1425059A (de)
HU (1) HU166354B (de)
IE (1) IE37773B1 (de)
IL (1) IL42458A (de)
NL (1) NL7308059A (de)
SU (5) SU511856A3 (de)
ZA (1) ZA733880B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3981882A (en) * 1972-08-31 1976-09-21 Bayer Aktiengesellschaft Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester
US3971796A (en) * 1973-07-12 1976-07-27 Bayer Aktiengesellschaft 1,4-Dihydropyridine esters
US4466972A (en) * 1977-06-20 1984-08-21 Sandoz Ltd. Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4252956A (en) * 1979-03-19 1981-02-24 Vigante Brigita A Derivatives of 1,4-dihydropyridine-3-carbothiol acids
GB2111978B (en) * 1981-10-19 1985-05-01 Maruko Pharmaceutical Co 1 4-dihydropyridine compounds
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IE57810B1 (en) * 1984-03-27 1993-04-21 Delagrange Lab 1,4-dihydropyridine derivatives,their preparation and their use
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
JPS60210640A (ja) * 1984-10-05 1985-10-23 Hitachi Chem Co Ltd 積層板の製造法
GB8503427D0 (en) * 1985-02-11 1985-03-13 Ici Plc Basic compounds
GB8503425D0 (en) * 1985-02-11 1985-03-13 Ici Plc Alkanolamine derivatives
GB8503428D0 (en) * 1985-02-11 1985-03-13 Ici Plc Nitrogen-containing compounds
GB8503429D0 (en) * 1985-02-11 1985-03-13 Ici Plc Chemical compounds
US4593033A (en) * 1985-04-24 1986-06-03 Merck & Co., Inc. Substituted indeno[2,1-c] pyridines useful as calcium channel blockers
US4605660A (en) * 1985-06-03 1986-08-12 Merck & Co., Inc. Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers
US4670443A (en) * 1985-07-02 1987-06-02 Merck & Co., Inc. Benzo(f)isoquinoline compounds useful as calcium entry blockers
NL192385C (nl) * 1985-08-21 1997-07-04 Glaxo Spa 6-alkyl-4-fenyl-1,4-dihydro-3,5-pyridinecarbonzuuresters, werkwijze voor de bereiding daarvan en farmaceutische preparaten die deze esters bevatten.
EP0226271B1 (de) * 1985-08-21 1990-11-22 GLAXO S.p.A. 1,4-Dihydropyridinverbindungen und ihre Herstellung und pharmazeutische Formulierung
US4735956A (en) * 1985-09-13 1988-04-05 Merck & Co., Inc. Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
US4721708A (en) * 1985-11-26 1988-01-26 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use
US4788203A (en) * 1985-11-26 1988-11-29 Merck & Co., Inc. Cyclized N-substituted-tetrahydropyridine compounds, useful in the treatment of cardiovascular disorders
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
EP0330470A3 (de) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. Gegen Tumorzellen verwendbare 1,4-Dihydropyridin-Derivate
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.
WO2000005209A1 (en) * 1998-07-23 2000-02-03 Lin, Tong-Ho GUAIACOXYPROPANOLAMINES WITH α/β-ADRENERGIC BLOCKING ACTIVITY
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US20030153773A1 (en) * 2002-02-14 2003-08-14 Wayne Gregory S. Process for the production of dihydropyridines
WO2005016885A2 (en) * 2003-08-14 2005-02-24 Artesian Therapeutics, Inc. COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
DE2003146A1 (de) * 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate

Also Published As

Publication number Publication date
ZA733880B (en) 1974-05-29
ES440620A1 (es) 1977-03-01
ES440621A1 (es) 1977-03-01
BE800679A (fr) 1973-12-10
CH591443A5 (de) 1977-09-15
SU512708A3 (ru) 1976-04-30
CH589629A5 (de) 1977-07-15
GB1425059A (en) 1976-02-18
FR2187347A1 (de) 1974-01-18
AT329561B (de) 1976-05-25
AU473996B2 (en) 1976-07-08
CH588462A5 (de) 1977-06-15
AU5672573A (en) 1974-12-12
ES415749A1 (es) 1976-06-16
CS178888B2 (en) 1977-10-31
ATA507473A (de) 1975-06-15
JPS4948680A (de) 1974-05-11
DE2228363A1 (de) 1974-01-03
CH591444A5 (de) 1977-09-15
ES440619A1 (es) 1977-03-01
IE37773L (en) 1973-12-10
CS178899B2 (en) 1977-10-31
ES440622A1 (es) 1977-03-01
CA999592A (en) 1976-11-09
IL42458A0 (en) 1973-08-29
CH589058A5 (de) 1977-06-30
SU509221A3 (ru) 1976-03-30
CH593260A5 (de) 1977-11-30
HU166354B (de) 1975-03-28
SU511856A3 (ru) 1976-04-25
IE37773B1 (en) 1977-10-12
AT328447B (de) 1976-03-25
NL7308059A (de) 1973-12-12
US3923818A (en) 1975-12-02
CS178900B2 (en) 1977-10-31
DD109383A5 (de) 1974-11-05
CS178897B2 (en) 1977-10-31
CS178898B2 (en) 1977-10-31
SU507234A3 (ru) 1976-03-15
ATA177075A (de) 1975-08-15
CH589628A5 (de) 1977-07-15
SU510997A3 (ru) 1976-04-15
FR2187347B1 (de) 1977-09-09

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