IL39341A - Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents
Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL39341A IL39341A IL39341A IL3934172A IL39341A IL 39341 A IL39341 A IL 39341A IL 39341 A IL39341 A IL 39341A IL 3934172 A IL3934172 A IL 3934172A IL 39341 A IL39341 A IL 39341A
- Authority
- IL
- Israel
- Prior art keywords
- thieno
- pyrimidines
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712121950 DE2121950A1 (en) | 1971-05-04 | 1971-05-04 | Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity |
| DE19712137341 DE2137341A1 (de) | 1971-07-26 | 1971-07-26 | Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine |
| DE19722215299 DE2215299A1 (de) | 1972-03-29 | 1972-03-29 | Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL39341A0 IL39341A0 (en) | 1972-07-26 |
| IL39341A true IL39341A (en) | 1975-08-31 |
Family
ID=27183398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL39341A IL39341A (en) | 1971-05-04 | 1972-05-03 | Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them |
Country Status (15)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4054656A (en) * | 1975-09-10 | 1977-10-18 | Mead Johnson & Company | Thieno[2,3-d]pyrimidine antiallergic agents |
| US5098902A (en) * | 1991-03-18 | 1992-03-24 | Warner-Lambert Company | Method of treating neurodegenerative diseases |
| FI943798A0 (fi) * | 1992-02-19 | 1994-08-18 | Pfizer | Kasvaimenvastaisen vaikutuksen lisäämiseen tarkoitettuja heterosyklisiä yhdisteitä |
| KR100378937B1 (ko) | 1997-10-20 | 2003-05-09 | 에프. 호프만-라 로슈 아게 | 바이사이클릭 키나아제 억제제 |
| US6187777B1 (en) | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
| GB0423653D0 (en) | 2004-10-25 | 2004-11-24 | Piramed Ltd | Pharmaceutical compounds |
| BRPI0608387A2 (pt) * | 2006-04-19 | 2009-12-29 | Boehringer Ingelheim Int | compostos para o tratamento de doenças inflamatórias |
| CL2007001166A1 (es) | 2006-04-26 | 2008-01-25 | Piramed Ltd | Compuestos derivados de pirimidina condensada, inhibidores de pi3-quinasa; procesos para preparar los compuestos; composicion farmaceutica que los comprende; uso de los compuestos en la preparacion de medicamentos; proceso para preparar la composicion farmaceutica; y kit que incluye a la composicion farmaceutica |
| CN101472930B (zh) | 2006-04-26 | 2011-12-14 | 霍夫曼-拉罗奇有限公司 | 用作PI3K抑制剂的噻吩并[3,2-d]嘧啶的衍生物 |
| PT2041139E (pt) | 2006-04-26 | 2012-01-13 | Hoffmann La Roche | Compostos farmacêuticos |
| BRPI0717923A2 (pt) | 2006-12-07 | 2013-10-22 | Genentech In | '' composto, composição farmacêutica, método para tratar um câncer, processo para a produção de uma composição farmacêutica, usos, métodos para inibir ou modular a atividade da lipídeo quinase e kit ' ' |
| ZA200904531B (en) | 2006-12-07 | 2010-09-29 | Hoffmann La Roche | Phosphoinositide 3-kinase inhibitor compounds and methods of use |
| EP2207781B1 (en) | 2007-09-24 | 2012-11-28 | Genentech, Inc. | Thiazolopyrimidine p13k inhibitor compounds and methods of use |
| NZ585348A (en) * | 2007-10-19 | 2012-02-24 | Boehringer Ingelheim Int | Heterocycle-substituted piperazino-dihydrothienopyrimidines |
| EP2214675B1 (en) | 2007-10-25 | 2013-11-20 | Genentech, Inc. | Process for making thienopyrimidine compounds |
| GB0721095D0 (en) | 2007-10-26 | 2007-12-05 | Piramed Ltd | Pharmaceutical compounds |
| AU2010224125B2 (en) | 2009-03-12 | 2015-05-14 | Genentech, Inc. | Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies |
| WO2010136491A1 (en) * | 2009-05-27 | 2010-12-02 | F. Hoffmann-La Roche Ag | Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
| EP2435438A1 (en) | 2009-05-27 | 2012-04-04 | Genentech, Inc. | Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use |
| WO2011130654A1 (en) | 2010-04-16 | 2011-10-20 | Genentech, Inc. | Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy |
| US20140004209A1 (en) | 2010-12-22 | 2014-01-02 | Genentech, Inc. | Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms |
| MX369175B (es) | 2013-02-25 | 2019-10-30 | Genentech Inc | Métodos para detectar mutantes de akt resistentes a fármacos. |
| GB201410816D0 (en) * | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3259623A (en) * | 1963-06-14 | 1966-07-05 | Olin Mathieson | Process for preparing 2-(secondary amino)-halogenopyrimidines |
| DE1470356A1 (de) * | 1964-01-15 | 1970-04-30 | Thomae Gmbh Dr K | Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung |
| US3210368A (en) * | 1964-09-29 | 1965-10-05 | Ciba Geigy Corp | Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds |
-
1972
- 1972-04-28 RO RO7200070735A patent/RO62428A/ro unknown
- 1972-05-02 ES ES402302A patent/ES402302A1/es not_active Expired
- 1972-05-02 HU HUTO875A patent/HU163960B/hu unknown
- 1972-05-03 AT AT382972A patent/AT318619B/de not_active IP Right Cessation
- 1972-05-03 BG BG020371A patent/BG20593A3/xx unknown
- 1972-05-03 DK DK219672AA patent/DK129844B/da unknown
- 1972-05-03 GB GB2058472A patent/GB1393161A/en not_active Expired
- 1972-05-03 PL PL1972155128A patent/PL82381B1/pl unknown
- 1972-05-03 US US249782A patent/US3888851A/en not_active Expired - Lifetime
- 1972-05-03 IL IL39341A patent/IL39341A/xx unknown
- 1972-05-03 AU AU41815/72A patent/AU4181572A/en not_active Expired
- 1972-05-03 DD DD162711A patent/DD97656A5/xx unknown
- 1972-05-04 FR FR7215929A patent/FR2135294B1/fr not_active Expired
- 1972-05-04 NL NL7206041A patent/NL7206041A/xx unknown
- 1972-05-04 BE BE783044A patent/BE783044A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1393161A (en) | 1975-05-07 |
| DK129844C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-05-12 |
| FR2135294A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-12-15 |
| AT318619B (de) | 1974-11-11 |
| IL39341A0 (en) | 1972-07-26 |
| FR2135294B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-17 |
| DD97656A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-05-12 |
| NL7206041A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-11-07 |
| ES402302A1 (es) | 1975-04-01 |
| RO62428A (fr) | 1978-01-15 |
| BG20593A3 (bg) | 1975-12-05 |
| US3888851A (en) | 1975-06-10 |
| BE783044A (fr) | 1972-11-06 |
| PL82381B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-31 |
| AU4181572A (en) | 1973-11-08 |
| HU163960B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-11-28 |
| DK129844B (da) | 1974-11-25 |
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