IL37560A - 15-methyl prostaglandin a1 and a2 compounds - Google Patents
15-methyl prostaglandin a1 and a2 compoundsInfo
- Publication number
- IL37560A IL37560A IL37560A IL3756071A IL37560A IL 37560 A IL37560 A IL 37560A IL 37560 A IL37560 A IL 37560A IL 3756071 A IL3756071 A IL 3756071A IL 37560 A IL37560 A IL 37560A
- Authority
- IL
- Israel
- Prior art keywords
- pge
- formulμ
- cis
- trans
- neutral
- Prior art date
Links
- BGKHCLZFGPIKKU-UHFFFAOYSA-N (13E,15S)-15-hydroxy-9-oxo-prosta-10,13-dienoic acid Natural products CCCCCC(O)C=CC1C=CC(=O)C1CCCCCCC(O)=O BGKHCLZFGPIKKU-UHFFFAOYSA-N 0.000 title 1
- MYHXHCUNDDAEOZ-UHFFFAOYSA-N Prostaglandin A&2% Natural products CCCCCC(O)C=CC1C=CC(=O)C1CC=CCCCC(O)=O MYHXHCUNDDAEOZ-UHFFFAOYSA-N 0.000 title 1
- 150000003155 prostaglandin A2 derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 8
- 229910052799 carbon Inorganic materials 0.000 claims abstract 4
- 230000007935 neutral effect Effects 0.000 claims abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 3
- 239000012024 dehydrating agents Substances 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 229910052802 copper Inorganic materials 0.000 claims 1
- 239000010949 copper Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 2
- 150000003180 prostaglandins Chemical class 0.000 abstract 2
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7210570A | 1970-09-14 | 1970-09-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL37560A0 IL37560A0 (en) | 1971-11-29 |
| IL37560A true IL37560A (en) | 1976-04-30 |
Family
ID=22105603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL37560A IL37560A (en) | 1970-09-14 | 1971-08-24 | 15-methyl prostaglandin a1 and a2 compounds |
Country Status (12)
| Country | Link |
|---|---|
| AU (1) | AU456371B2 (cs) |
| BE (1) | BE772584A (cs) |
| CA (1) | CA950901A (cs) |
| DE (1) | DE2145600A1 (cs) |
| ES (1) | ES395036A2 (cs) |
| FR (1) | FR2106500B1 (cs) |
| GB (1) | GB1314292A (cs) |
| IL (1) | IL37560A (cs) |
| NL (1) | NL7112466A (cs) |
| PH (1) | PH12134A (cs) |
| SU (1) | SU399108A3 (cs) |
| ZA (1) | ZA715518B (cs) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3892795A (en) * | 1971-04-12 | 1975-07-01 | Upjohn Co | 16-Methyl and 16,16 dimethyl PGA{HD 2 {B compounds |
| US3954832A (en) * | 1972-07-24 | 1976-05-04 | The Upjohn Company | 16-And 16,16-methyl and ethyl substituted PGA1 -type compounds |
-
1971
- 1971-08-16 CA CA120,632,A patent/CA950901A/en not_active Expired
- 1971-08-18 GB GB3878271A patent/GB1314292A/en not_active Expired
- 1971-08-18 ZA ZA715518A patent/ZA715518B/xx unknown
- 1971-08-24 IL IL37560A patent/IL37560A/en unknown
- 1971-08-25 PH PH12784A patent/PH12134A/en unknown
- 1971-09-10 NL NL7112466A patent/NL7112466A/xx unknown
- 1971-09-13 AU AU33396/71A patent/AU456371B2/en not_active Expired
- 1971-09-13 SU SU1695975A patent/SU399108A3/ru active
- 1971-09-13 ES ES395036A patent/ES395036A2/es not_active Expired
- 1971-09-13 FR FR7132974A patent/FR2106500B1/fr not_active Expired
- 1971-09-13 DE DE19712145600 patent/DE2145600A1/de active Pending
- 1971-09-14 BE BE772584A patent/BE772584A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU3339671A (en) | 1973-03-22 |
| PH12134A (en) | 1978-11-07 |
| CA950901A (en) | 1974-07-09 |
| DE2145600A1 (de) | 1972-03-16 |
| IL37560A0 (en) | 1971-11-29 |
| NL7112466A (cs) | 1972-03-16 |
| AU456371B2 (en) | 1974-12-19 |
| FR2106500B1 (cs) | 1974-11-15 |
| ZA715518B (en) | 1972-05-31 |
| SU399108A3 (cs) | 1973-09-27 |
| BE772584A (fr) | 1972-03-14 |
| ES395036A2 (es) | 1973-12-16 |
| GB1314292A (en) | 1973-04-18 |
| FR2106500A1 (cs) | 1972-05-05 |
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