IL36671A - 1-alkoxyalkyl(cycloalkylalkyl)-5-(o-alkylphenyl)-7-halo-1,3-dihydro-2h-1,4-benzodiazepin-2-ones,processes for their preparation and pharmaceutical compositions containing the same - Google Patents

1-alkoxyalkyl(cycloalkylalkyl)-5-(o-alkylphenyl)-7-halo-1,3-dihydro-2h-1,4-benzodiazepin-2-ones,processes for their preparation and pharmaceutical compositions containing the same

Info

Publication number
IL36671A
IL36671A IL36671A IL3667171A IL36671A IL 36671 A IL36671 A IL 36671A IL 36671 A IL36671 A IL 36671A IL 3667171 A IL3667171 A IL 3667171A IL 36671 A IL36671 A IL 36671A
Authority
IL
Israel
Prior art keywords
benzodiazepin
cycloalkylalkyl
alkylphenyl
alkoxyalkyl
dihydro
Prior art date
Application number
IL36671A
Other versions
IL36671A0 (en
Original Assignee
Sumitomo Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP45035735A external-priority patent/JPS494226B1/ja
Priority claimed from JP4149870A external-priority patent/JPS499474B1/ja
Priority claimed from JP4149970A external-priority patent/JPS4911238B1/ja
Application filed by Sumitomo Chemical Co filed Critical Sumitomo Chemical Co
Publication of IL36671A0 publication Critical patent/IL36671A0/en
Publication of IL36671A publication Critical patent/IL36671A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • C07D243/32Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings containing a phthalimide or hydrogenated phthalimide ring system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Package Closures (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL36671A 1970-04-23 1971-04-21 1-alkoxyalkyl(cycloalkylalkyl)-5-(o-alkylphenyl)-7-halo-1,3-dihydro-2h-1,4-benzodiazepin-2-ones,processes for their preparation and pharmaceutical compositions containing the same IL36671A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP45035735A JPS494226B1 (en) 1970-04-23 1970-04-23
JP4149870A JPS499474B1 (en) 1970-05-14 1970-05-14
JP4149970A JPS4911238B1 (en) 1970-05-14 1970-05-14

Publications (2)

Publication Number Publication Date
IL36671A0 IL36671A0 (en) 1971-06-23
IL36671A true IL36671A (en) 1975-02-10

Family

ID=27288853

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36671A IL36671A (en) 1970-04-23 1971-04-21 1-alkoxyalkyl(cycloalkylalkyl)-5-(o-alkylphenyl)-7-halo-1,3-dihydro-2h-1,4-benzodiazepin-2-ones,processes for their preparation and pharmaceutical compositions containing the same

Country Status (7)

Country Link
BE (1) BE766098A (en)
DE (1) DE2166444A1 (en)
FR (1) FR2092074B1 (en)
GB (1) GB1307144A (en)
IL (1) IL36671A (en)
NL (1) NL7105495A (en)
NO (1) NO132869C (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL138936B (en) * 1967-12-06 1973-05-15 Sumitomo Chemical Co PROCESS FOR PREPARING BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL PREPARATION PREPARED FROM THIS.
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives

Also Published As

Publication number Publication date
GB1307144A (en) 1973-02-14
NO132869C (en) 1976-01-21
FR2092074A1 (en) 1972-01-21
IL36671A0 (en) 1971-06-23
NL7105495A (en) 1971-10-26
FR2092074B1 (en) 1974-10-18
BE766098A (en) 1971-09-16
DE2166444A1 (en) 1974-02-21
NO132869B (en) 1975-10-13

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