IL36323A - 16-methylene-9 beta,10 alpha-steroids of the pregnane series,their production and pharmaceutical compositions containing them - Google Patents

16-methylene-9 beta,10 alpha-steroids of the pregnane series,their production and pharmaceutical compositions containing them

Info

Publication number
IL36323A
IL36323A IL36323A IL3632371A IL36323A IL 36323 A IL36323 A IL 36323A IL 36323 A IL36323 A IL 36323A IL 3632371 A IL3632371 A IL 3632371A IL 36323 A IL36323 A IL 36323A
Authority
IL
Israel
Prior art keywords
steroids
methylene
beta
alpha
production
Prior art date
Application number
IL36323A
Other languages
English (en)
Other versions
IL36323A0 (en
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Publication of IL36323A0 publication Critical patent/IL36323A0/xx
Publication of IL36323A publication Critical patent/IL36323A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0084—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkylene group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL36323A 1970-03-04 1971-03-02 16-methylene-9 beta,10 alpha-steroids of the pregnane series,their production and pharmaceutical compositions containing them IL36323A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7003061A NL7003061A (ja) 1970-03-04 1970-03-04

Publications (2)

Publication Number Publication Date
IL36323A0 IL36323A0 (en) 1971-05-26
IL36323A true IL36323A (en) 1975-02-10

Family

ID=19809487

Family Applications (1)

Application Number Title Priority Date Filing Date
IL36323A IL36323A (en) 1970-03-04 1971-03-02 16-methylene-9 beta,10 alpha-steroids of the pregnane series,their production and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (1) US3759960A (ja)
JP (8) JPS5037664B1 (ja)
AR (5) AR192741A1 (ja)
AT (9) AT313494B (ja)
BE (1) BE763753A (ja)
CA (1) CA945544A (ja)
DE (1) DE2109348A1 (ja)
ES (1) ES388852A1 (ja)
FR (1) FR2085670B1 (ja)
GB (1) GB1336763A (ja)
IL (1) IL36323A (ja)
NL (1) NL7003061A (ja)
SE (1) SE373748B (ja)
ZA (1) ZA711290B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59139398A (ja) * 1983-01-12 1984-08-10 Daikin Ind Ltd 含フッ素ステロイド化合物の製法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3198792A (en) * 1962-06-12 1965-08-03 Philips Corp 10alpha methyl, 9beta hormonal steroids
DE1277253B (de) * 1963-01-19 1968-09-12 Merck Ag E Ungesaettigte 16-Methylen-17ª‡-alkoxy-3, 20-diketo-steroide der Pregnanreihe sowie ein Verfahren zu ihrer Herstellung
US3493588A (en) * 1968-03-25 1970-02-03 Schering Corp Process for the preparation of 6-chloro-16-methylene - 17alpha - lower alkanoyloxy-4,6-pregnadiene-3,20-dione and novel intermediates produced thereby

Also Published As

Publication number Publication date
AR192742A1 (es) 1973-03-14
AR192741A1 (es) 1973-03-14
JPS50105659A (ja) 1975-08-20
JPS50142557A (ja) 1975-11-17
AR192737A1 (es) 1973-03-14
JPS50105655A (ja) 1975-08-20
CA945544A (en) 1974-04-16
AT312174B (de) 1973-12-27
FR2085670A1 (ja) 1971-12-31
AT313493B (de) 1974-01-15
AT313498B (de) 1974-01-15
AT313497B (de) 1974-01-15
JPS50105652A (ja) 1975-08-20
AT313496B (de) 1974-01-15
FR2085670B1 (ja) 1974-08-02
JPS50105651A (ja) 1975-08-20
AT314748B (de) 1974-03-15
AT313495B (de) 1974-01-15
DE2109348A1 (de) 1971-09-16
AT313494B (de) 1974-01-15
AT314100B (de) 1974-03-25
JPS5037664B1 (ja) 1975-12-04
US3759960A (en) 1973-09-18
ES388852A1 (es) 1973-06-01
SE373748B (ja) 1975-02-17
ZA711290B (en) 1972-10-25
JPS50105654A (ja) 1975-08-20
IL36323A0 (en) 1971-05-26
BE763753A (fr) 1971-09-03
NL7003061A (ja) 1971-09-07
GB1336763A (en) 1973-11-07
JPS50105653A (ja) 1975-08-20
AR192739A1 (es) 1973-03-14
AR192740A1 (es) 1973-03-14

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