IL34431A - Substituted 1,2alpha-methylene-20-spirox-4-ene-3-ones or 3-ols,acyl esters thereof and their preparation - Google Patents

Substituted 1,2alpha-methylene-20-spirox-4-ene-3-ones or 3-ols,acyl esters thereof and their preparation

Info

Publication number
IL34431A
IL34431A IL34431A IL3443170A IL34431A IL 34431 A IL34431 A IL 34431A IL 34431 A IL34431 A IL 34431A IL 3443170 A IL3443170 A IL 3443170A IL 34431 A IL34431 A IL 34431A
Authority
IL
Israel
Prior art keywords
spirox
2alpha
ols
ene
methylene
Prior art date
Application number
IL34431A
Other languages
English (en)
Other versions
IL34431A0 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IL34431A0 publication Critical patent/IL34431A0/xx
Publication of IL34431A publication Critical patent/IL34431A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL34431A 1969-05-14 1970-05-01 Substituted 1,2alpha-methylene-20-spirox-4-ene-3-ones or 3-ols,acyl esters thereof and their preparation IL34431A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (2)

Publication Number Publication Date
IL34431A0 IL34431A0 (en) 1970-07-19
IL34431A true IL34431A (en) 1974-03-14

Family

ID=26694377

Family Applications (1)

Application Number Title Priority Date Filing Date
IL34431A IL34431A (en) 1969-05-14 1970-05-01 Substituted 1,2alpha-methylene-20-spirox-4-ene-3-ones or 3-ols,acyl esters thereof and their preparation

Country Status (17)

Country Link
JP (1) JPS532865B1 (is")
AR (1) AR192305A1 (is")
BE (1) BE750330A (is")
CA (1) CA926385A (is")
CH (2) CH547792A (is")
CS (2) CS151552B2 (is")
DE (1) DE2023450C3 (is")
DK (3) DK126992B (is")
FI (2) FI47355C (is")
FR (1) FR2051526B1 (is")
GB (1) GB1265444A (is")
IE (1) IE34194B1 (is")
IL (1) IL34431A (is")
NL (1) NL168844C (is")
NO (1) NO131131C (is")
SE (2) SE386904B (is")
YU (1) YU34052B (is")

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
NL168844B (nl) 1981-12-16
CS151552B2 (is") 1973-10-19
YU117670A (en) 1978-05-15
SE366305B (is") 1974-04-22
IE34194L (en) 1970-11-14
AR192305A1 (es) 1973-02-14
CA926385A (en) 1973-05-15
NL7006474A (is") 1970-11-17
CS151551B2 (is") 1973-10-19
JPS532865B1 (is") 1978-02-01
DE2023450B2 (de) 1978-10-05
DE2023450A1 (de) 1971-01-14
DE2023450C3 (de) 1979-05-31
CH547785A (de) 1974-04-11
NO131131C (is") 1975-04-09
FI47885B (is") 1974-01-02
FI47355C (fi) 1973-11-12
NO131131B (is") 1974-12-30
YU34052B (en) 1978-10-31
SE386904B (sv) 1976-08-23
BE750330A (fr) 1970-11-13
GB1265444A (is") 1972-03-01
FR2051526A1 (is") 1971-04-09
IE34194B1 (en) 1975-03-05
CH547792A (de) 1974-04-11
DK127505B (da) 1973-11-19
FI47355B (is") 1973-07-31
FR2051526B1 (is") 1974-04-12
DK126992B (da) 1973-09-10
NL168844C (nl) 1982-05-17
IL34431A0 (en) 1970-07-19
DK127880C (da) 1974-06-10
DK127880B (is") 1974-01-28
FI47885C (fi) 1974-04-10

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