IL326812A - חומרים טטראציקליים, תכשירים המכילים אותם ושימושיהם - Google Patents

חומרים טטראציקליים, תכשירים המכילים אותם ושימושיהם

Info

Publication number
IL326812A
IL326812A IL326812A IL32681226A IL326812A IL 326812 A IL326812 A IL 326812A IL 326812 A IL326812 A IL 326812A IL 32681226 A IL32681226 A IL 32681226A IL 326812 A IL326812 A IL 326812A
Authority
IL
Israel
Prior art keywords
compositions
methods
tetracyclic derivatives
tetracyclic
derivatives
Prior art date
Application number
IL326812A
Other languages
English (en)
Inventor
Deng Hongbo
Liu Tao
Original Assignee
Ensem Therapeutics Inc
Deng Hongbo
Liu Tao
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ensem Therapeutics Inc, Deng Hongbo, Liu Tao filed Critical Ensem Therapeutics Inc
Publication of IL326812A publication Critical patent/IL326812A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL326812A 2023-08-25 2024-08-23 חומרים טטראציקליים, תכשירים המכילים אותם ושימושיהם IL326812A (he)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202363534797P 2023-08-25 2023-08-25
US202463627442P 2024-01-31 2024-01-31
PCT/US2024/043554 WO2025049274A2 (en) 2023-08-25 2024-08-23 Tetracyclic derivatives, compositions and methods thereof

Publications (1)

Publication Number Publication Date
IL326812A true IL326812A (he) 2026-04-01

Family

ID=94820114

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326812A IL326812A (he) 2023-08-25 2024-08-23 חומרים טטראציקליים, תכשירים המכילים אותם ושימושיהם

Country Status (4)

Country Link
AU (1) AU2024334504A1 (he)
IL (1) IL326812A (he)
TW (1) TW202523668A (he)
WO (1) WO2025049274A2 (he)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
US20250375445A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117677624A (zh) * 2021-07-19 2024-03-08 上海艾力斯医药科技股份有限公司 新型吡啶并嘧啶衍生物
WO2023001141A1 (en) * 2021-07-23 2023-01-26 Shanghai Zion Pharma Co. Limited Kras g12d inhibitors and uses thereof
TW202315626A (zh) * 2021-08-31 2023-04-16 大陸商勁方醫藥科技(上海)有限公司 嘧啶并環類化合物及其製法和用途

Also Published As

Publication number Publication date
TW202523668A (zh) 2025-06-16
WO2025049274A2 (en) 2025-03-06
WO2025049274A3 (en) 2025-05-08
AU2024334504A1 (en) 2026-04-09

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