IL326614A - שיטות להכנת תרכובות פוספונאמידט - Google Patents

שיטות להכנת תרכובות פוספונאמידט

Info

Publication number
IL326614A
IL326614A IL326614A IL32661426A IL326614A IL 326614 A IL326614 A IL 326614A IL 326614 A IL326614 A IL 326614A IL 32661426 A IL32661426 A IL 32661426A IL 326614 A IL326614 A IL 326614A
Authority
IL
Israel
Prior art keywords
preparing
methods
phosphonamidate compounds
phosphonamidate
compounds
Prior art date
Application number
IL326614A
Other languages
English (en)
Inventor
Marc-Andre Kasper
Olivier Marcq
Paul Machui
Dominik Schumacher
Jonas Helma-Smets
Marcus Gerlach
Original Assignee
Tubulis Gmbh
Kasper Marc Andre
Olivier Marcq
Paul Machui
Dominik Schumacher
Helma Smets Jonas
Marcus Gerlach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tubulis Gmbh, Kasper Marc Andre, Olivier Marcq, Paul Machui, Dominik Schumacher, Helma Smets Jonas, Marcus Gerlach filed Critical Tubulis Gmbh
Publication of IL326614A publication Critical patent/IL326614A/he

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44Amides thereof
    • C07F9/4461Amides thereof the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4476Amides thereof the amide moiety containing a substituent or a structure which is considered as characteristic of aromatic amines (N-C aromatic linkage)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
IL326614A 2023-09-01 2024-08-30 שיטות להכנת תרכובות פוספונאמידט IL326614A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23194788 2023-09-01
PCT/EP2024/074322 WO2025046090A1 (en) 2023-09-01 2024-08-30 Methods of preparing phosphonamidate compounds

Publications (1)

Publication Number Publication Date
IL326614A true IL326614A (he) 2026-04-01

Family

ID=87929188

Family Applications (1)

Application Number Title Priority Date Filing Date
IL326614A IL326614A (he) 2023-09-01 2024-08-30 שיטות להכנת תרכובות פוספונאמידט

Country Status (3)

Country Link
AU (1) AU2024332412A1 (he)
IL (1) IL326614A (he)
WO (1) WO2025046090A1 (he)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4658320A1 (en) 2024-02-27 2025-12-10 Bristol-Myers Squibb Company Anti-ceacam5 antibody drug conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0401384B1 (en) 1988-12-22 1996-03-13 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
JP2763020B2 (ja) 1995-04-27 1998-06-11 日本電気株式会社 半導体パッケージ及び半導体装置
US5672662A (en) 1995-07-07 1997-09-30 Shearwater Polymers, Inc. Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
EP1731174A3 (en) 1996-08-02 2007-01-17 Ortho-McNeil Pharmaceutical, Inc. Polypeptides having a covalently bound N-terminal polyethylene glycol via hydrazone or oxime bond
AU2017320913B2 (en) 2016-09-01 2024-08-15 Forschungsverbund Berlin E.V. Chemoselective thiol-conjugation with alkene or alkyne-phosphonamidates
JP7429191B2 (ja) 2018-03-07 2024-02-07 フォルシュングスフェアバント ベルリン エー.ベー. アルケンホスホノチオレートまたはアルキンホスホノチオレートおよびアルケンホスホネートまたはアルキンホスホネートとの化学選択的チオールコンジュゲーション
TW202339803A (zh) 2021-11-09 2023-10-16 德商圖布里斯有限公司 包含磷(v)及喜樹鹼分子部分的共軛物
CN118302197A (zh) 2021-11-09 2024-07-05 Tubulis 股份有限公司 包含磷(v)和药物部分的偶联物

Also Published As

Publication number Publication date
WO2025046090A1 (en) 2025-03-06
AU2024332412A1 (en) 2026-03-12

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