IL325043A - תהליך להכנת 1-אתיל-n-((1,2,3,5,6,7-הקסהידרו-s-אינדצן-4-יל)קרבמויל)פיפרידין-4-סולפונמיד - Google Patents

תהליך להכנת 1-אתיל-n-((1,2,3,5,6,7-הקסהידרו-s-אינדצן-4-יל)קרבמויל)פיפרידין-4-סולפונמיד

Info

Publication number
IL325043A
IL325043A IL325043A IL32504325A IL325043A IL 325043 A IL325043 A IL 325043A IL 325043 A IL325043 A IL 325043A IL 32504325 A IL32504325 A IL 32504325A IL 325043 A IL325043 A IL 325043A
Authority
IL
Israel
Prior art keywords
compound
reaction mixture
reaction
toluene
reaction step
Prior art date
Application number
IL325043A
Other languages
English (en)
Inventor
Eike Johannes Bergner
Jos?Phine Eliette Fran?Oise Cinqualbre
Dainis Kaldre
Original Assignee
Hoffmann La Roche
Eike Johannes Bergner
Jos?Phine Eliette Fran?Oise Cinqualbre
Dainis Kaldre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Eike Johannes Bergner, Jos?Phine Eliette Fran?Oise Cinqualbre, Dainis Kaldre filed Critical Hoffmann La Roche
Publication of IL325043A publication Critical patent/IL325043A/he

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL325043A 2023-08-16 2024-08-14 תהליך להכנת 1-אתיל-n-((1,2,3,5,6,7-הקסהידרו-s-אינדצן-4-יל)קרבמויל)פיפרידין-4-סולפונמיד IL325043A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23191567 2023-08-16
PCT/EP2024/072842 WO2025036914A1 (en) 2023-08-16 2024-08-14 Process for the preparation of preparing 1-ethyl-n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide

Publications (1)

Publication Number Publication Date
IL325043A true IL325043A (he) 2026-01-01

Family

ID=87580339

Family Applications (1)

Application Number Title Priority Date Filing Date
IL325043A IL325043A (he) 2023-08-16 2024-08-14 תהליך להכנת 1-אתיל-n-((1,2,3,5,6,7-הקסהידרו-s-אינדצן-4-יל)קרבמויל)פיפרידין-4-סולפונמיד

Country Status (6)

Country Link
CN (1) CN121666381A (he)
AU (1) AU2024323952A1 (he)
IL (1) IL325043A (he)
MX (1) MX2026001458A (he)
TW (1) TW202513046A (he)
WO (1) WO2025036914A1 (he)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ760129A (en) 2017-07-07 2025-12-19 Inflazome Ltd Novel sulfonamide carboxamide compounds
CA3219597A1 (en) 2021-06-23 2022-12-29 F. Hoffmann-La Roche Ag Novel process

Also Published As

Publication number Publication date
CN121666381A (zh) 2026-03-13
AU2024323952A1 (en) 2025-12-04
MX2026001458A (es) 2026-03-02
WO2025036914A1 (en) 2025-02-20
TW202513046A (zh) 2025-04-01

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