IL324002A - תרכובות ביציקליות לעיכוב קטוהקסוקינאז - Google Patents
תרכובות ביציקליות לעיכוב קטוהקסוקינאזInfo
- Publication number
- IL324002A IL324002A IL324002A IL32400225A IL324002A IL 324002 A IL324002 A IL 324002A IL 324002 A IL324002 A IL 324002A IL 32400225 A IL32400225 A IL 32400225A IL 324002 A IL324002 A IL 324002A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- methyl
- salt
- azetidinyl
- carbon
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363470070P | 2023-05-31 | 2023-05-31 | |
| PCT/US2024/031643 WO2024249612A1 (en) | 2023-05-31 | 2024-05-30 | Bicyclic compounds for ketohexokinase inhibition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL324002A true IL324002A (he) | 2025-12-01 |
Family
ID=91664008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL324002A IL324002A (he) | 2023-05-31 | 2025-10-16 | תרכובות ביציקליות לעיכוב קטוהקסוקינאז |
Country Status (6)
| Country | Link |
|---|---|
| KR (1) | KR20260022334A (he) |
| CN (1) | CN121568939A (he) |
| AU (1) | AU2024278772A1 (he) |
| IL (1) | IL324002A (he) |
| MX (1) | MX2025014314A (he) |
| WO (1) | WO2024249612A1 (he) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4131648A (en) | 1975-01-28 | 1978-12-26 | Alza Corporation | Structured orthoester and orthocarbonate drug delivery devices |
| US4093709A (en) | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
| US4180646A (en) | 1975-01-28 | 1979-12-25 | Alza Corporation | Novel orthoester polymers and orthocarbonate polymers |
| US4079038A (en) | 1976-03-05 | 1978-03-14 | Alza Corporation | Poly(carbonates) |
| US4304767A (en) | 1980-05-15 | 1981-12-08 | Sri International | Polymers of di- (and higher functionality) ketene acetals and polyols |
| US4946931A (en) | 1989-06-14 | 1990-08-07 | Pharmaceutical Delivery Systems, Inc. | Polymers containing carboxy-ortho ester and ortho ester linkages |
| US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
| US5968543A (en) | 1996-01-05 | 1999-10-19 | Advanced Polymer Systems, Inc. | Polymers with controlled physical state and bioerodibility |
| CN1378445B (zh) | 1999-08-06 | 2013-02-06 | 得克萨斯系统大学评议会 | 药物释放生物可降解纤维植入物 |
| US6613355B2 (en) | 2000-05-11 | 2003-09-02 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| US6524606B1 (en) | 2001-11-16 | 2003-02-25 | Ap Pharma, Inc. | Bioerodible polyorthoesters containing amine groups |
| KR102073048B1 (ko) | 2015-12-29 | 2020-02-04 | 화이자 인코포레이티드 | 케토헥소키나제 억제제로서의 치환된 3-아자비시클로[3.1.0]헥산 |
| TWI750685B (zh) | 2019-06-17 | 2021-12-21 | 美商美國禮來大藥廠 | 二取代吡唑化合物 |
| WO2022211595A1 (ko) * | 2021-04-01 | 2022-10-06 | 주식회사 엘지화학 | 옥사디아졸 화합물 및 이를 포함하는 약제학적 조성물 |
-
2024
- 2024-05-30 KR KR1020257043496A patent/KR20260022334A/ko active Pending
- 2024-05-30 AU AU2024278772A patent/AU2024278772A1/en active Pending
- 2024-05-30 CN CN202480035664.3A patent/CN121568939A/zh active Pending
- 2024-05-30 WO PCT/US2024/031643 patent/WO2024249612A1/en not_active Ceased
-
2025
- 2025-10-16 IL IL324002A patent/IL324002A/he unknown
- 2025-11-28 MX MX2025014314A patent/MX2025014314A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024249612A1 (en) | 2024-12-05 |
| MX2025014314A (es) | 2026-01-07 |
| AU2024278772A1 (en) | 2025-11-06 |
| KR20260022334A (ko) | 2026-02-19 |
| CN121568939A (zh) | 2026-02-24 |
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