IL321020A - Methods of administering certain vmat2 inhibitors - Google Patents

Methods of administering certain vmat2 inhibitors

Info

Publication number
IL321020A
IL321020A IL321020A IL32102025A IL321020A IL 321020 A IL321020 A IL 321020A IL 321020 A IL321020 A IL 321020A IL 32102025 A IL32102025 A IL 32102025A IL 321020 A IL321020 A IL 321020A
Authority
IL
Israel
Prior art keywords
vmat2
inhibitor
monoamine transporter
vesicular monoamine
amount
Prior art date
Application number
IL321020A
Other languages
English (en)
Hebrew (he)
Original Assignee
Neurocrine Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc
Publication of IL321020A publication Critical patent/IL321020A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL321020A 2019-05-09 2020-05-08 Methods of administering certain vmat2 inhibitors IL321020A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962845599P 2019-05-09 2019-05-09
PCT/US2020/032188 WO2020227672A1 (en) 2019-05-09 2020-05-08 Methods for the administration of certain vmat2 inhibitors

Publications (1)

Publication Number Publication Date
IL321020A true IL321020A (en) 2025-07-01

Family

ID=70919120

Family Applications (2)

Application Number Title Priority Date Filing Date
IL321020A IL321020A (en) 2019-05-09 2020-05-08 Methods of administering certain vmat2 inhibitors
IL287902A IL287902A (en) 2019-05-09 2021-11-08 Methods of administering certain vmat2 inhibitors

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL287902A IL287902A (en) 2019-05-09 2021-11-08 Methods of administering certain vmat2 inhibitors

Country Status (17)

Country Link
US (2) US20200397779A1 (enExample)
EP (1) EP3965764A1 (enExample)
JP (2) JP2022531696A (enExample)
KR (1) KR20220007105A (enExample)
CN (1) CN114340624A (enExample)
AU (2) AU2020270145A1 (enExample)
BR (1) BR112021020709A2 (enExample)
CA (1) CA3136466A1 (enExample)
EA (1) EA202193012A1 (enExample)
IL (2) IL321020A (enExample)
JO (1) JOP20210274A1 (enExample)
MA (1) MA55893A (enExample)
MX (1) MX2021013132A (enExample)
PH (1) PH12021552745A1 (enExample)
SG (1) SG11202111465RA (enExample)
TW (1) TWI850377B (enExample)
WO (1) WO2020227672A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230170136A (ko) 2017-01-27 2023-12-18 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
CA3076000A1 (en) 2017-09-21 2019-03-28 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto
KR20250070134A (ko) 2017-10-10 2025-05-20 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
US20200230127A1 (en) 2017-10-10 2020-07-23 Neurocrine Biosciences, Inc. Methods for the Administration of Certain VMAT2 Inhibitors
SG11202100303QA (en) 2018-08-15 2021-02-25 Neurocrine Biosciences Inc Methods for the administration of certain vmat2 inhibitors
IL309172A (en) * 2021-06-30 2024-02-01 Neurocrine Biosciences Inc Vulbanazine for use in the additional treatment of schizophrenia
CA3229341A1 (en) 2021-08-20 2023-02-23 Ryan TERRY-LORENZO Methods of screening for vmat2 inhibitors
CA3245030A1 (en) * 2022-03-07 2023-09-14 Neurocrine Biosciences, Inc. VALBENAZINE, A VMAT2 INHIBITOR, AS A FREE BASE OF A TOSYLATE OR DITOSYLATE SALT, INTENDED FOR USE IN THE TREATMENT OF CHOREA ASSOCIATED WITH HUNTINGTON'S DISEASE
TW202521119A (zh) * 2023-08-17 2025-06-01 美商紐羅克里生物科學有限公司 用於投與特定vmat2抑制劑之方法
WO2025038959A1 (en) * 2023-08-17 2025-02-20 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors
WO2025188830A1 (en) * 2024-03-06 2025-09-12 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US952A (en) 1838-09-27 I antoni bengini
US10065A (en) 1853-10-04 Improvement in machines for topping cotton jn the field
FI3936130T3 (fi) * 2014-05-06 2024-04-23 Neurocrine Biosciences Inc Valbenatsiinin annostusohjelma hyperkineettisten liikehäiriöiden hoitoon
US20190015396A1 (en) * 2015-06-23 2019-01-17 Neurocrine Biosciences, Inc. Vmat2 inhibitors for treating neurological diseases or disorders
KR20230170136A (ko) * 2017-01-27 2023-12-18 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
WO2018164996A1 (en) * 2017-03-06 2018-09-13 Neurocrine Biosciences, Inc. Dosing regimen for valbenazine
SG11202100303QA (en) * 2018-08-15 2021-02-25 Neurocrine Biosciences Inc Methods for the administration of certain vmat2 inhibitors

Also Published As

Publication number Publication date
KR20220007105A (ko) 2022-01-18
JP2025013963A (ja) 2025-01-28
MA55893A (fr) 2022-03-16
MX2021013132A (es) 2021-11-25
CA3136466A1 (en) 2020-11-12
EA202193012A1 (ru) 2022-03-02
TWI850377B (zh) 2024-08-01
BR112021020709A2 (pt) 2021-12-14
JOP20210274A1 (ar) 2023-01-30
US20220040169A1 (en) 2022-02-10
AU2020270145A1 (en) 2021-12-23
SG11202111465RA (en) 2021-11-29
IL287902A (en) 2022-01-01
PH12021552745A1 (en) 2022-07-11
US20200397779A1 (en) 2020-12-24
EP3965764A1 (en) 2022-03-16
WO2020227672A1 (en) 2020-11-12
JP2022531696A (ja) 2022-07-08
AU2025256123A1 (en) 2025-11-13
TW202108138A (zh) 2021-03-01
CN114340624A (zh) 2022-04-12

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