EA202193012A1 - Способы введения определенных ингибиторов vmat2 - Google Patents

Способы введения определенных ингибиторов vmat2

Info

Publication number
EA202193012A1
EA202193012A1 EA202193012A EA202193012A EA202193012A1 EA 202193012 A1 EA202193012 A1 EA 202193012A1 EA 202193012 A EA202193012 A EA 202193012A EA 202193012 A EA202193012 A EA 202193012A EA 202193012 A1 EA202193012 A1 EA 202193012A1
Authority
EA
Eurasian Patent Office
Prior art keywords
routes
administration
vmat2 inhibitors
certain
certain vmat2
Prior art date
Application number
EA202193012A
Other languages
English (en)
Russian (ru)
Inventor
Дао Туйет Тай-Куарто
Барбара Шольц
Грейс С. Лианг
Эйри У. Робертс
Original Assignee
Ньюрокрайн Байосайенсиз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ньюрокрайн Байосайенсиз, Инк. filed Critical Ньюрокрайн Байосайенсиз, Инк.
Publication of EA202193012A1 publication Critical patent/EA202193012A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EA202193012A 2019-05-09 2020-05-08 Способы введения определенных ингибиторов vmat2 EA202193012A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962845599P 2019-05-09 2019-05-09
PCT/US2020/032188 WO2020227672A1 (en) 2019-05-09 2020-05-08 Methods for the administration of certain vmat2 inhibitors

Publications (1)

Publication Number Publication Date
EA202193012A1 true EA202193012A1 (ru) 2022-03-02

Family

ID=70919120

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202193012A EA202193012A1 (ru) 2019-05-09 2020-05-08 Способы введения определенных ингибиторов vmat2

Country Status (17)

Country Link
US (2) US20200397779A1 (enExample)
EP (1) EP3965764A1 (enExample)
JP (2) JP2022531696A (enExample)
KR (1) KR20220007105A (enExample)
CN (1) CN114340624A (enExample)
AU (2) AU2020270145A1 (enExample)
BR (1) BR112021020709A2 (enExample)
CA (1) CA3136466A1 (enExample)
EA (1) EA202193012A1 (enExample)
IL (2) IL321020A (enExample)
JO (1) JOP20210274A1 (enExample)
MA (1) MA55893A (enExample)
MX (1) MX2021013132A (enExample)
PH (1) PH12021552745A1 (enExample)
SG (1) SG11202111465RA (enExample)
TW (1) TWI850377B (enExample)
WO (1) WO2020227672A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230170136A (ko) 2017-01-27 2023-12-18 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
CA3076000A1 (en) 2017-09-21 2019-03-28 Neurocrine Biosciences, Inc. High dosage valbenazine formulation and compositions, methods, and kits related thereto
KR20250070134A (ko) 2017-10-10 2025-05-20 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
US20200230127A1 (en) 2017-10-10 2020-07-23 Neurocrine Biosciences, Inc. Methods for the Administration of Certain VMAT2 Inhibitors
SG11202100303QA (en) 2018-08-15 2021-02-25 Neurocrine Biosciences Inc Methods for the administration of certain vmat2 inhibitors
IL309172A (en) * 2021-06-30 2024-02-01 Neurocrine Biosciences Inc Vulbanazine for use in the additional treatment of schizophrenia
CA3229341A1 (en) 2021-08-20 2023-02-23 Ryan TERRY-LORENZO Methods of screening for vmat2 inhibitors
CA3245030A1 (en) * 2022-03-07 2023-09-14 Neurocrine Biosciences, Inc. VALBENAZINE, A VMAT2 INHIBITOR, AS A FREE BASE OF A TOSYLATE OR DITOSYLATE SALT, INTENDED FOR USE IN THE TREATMENT OF CHOREA ASSOCIATED WITH HUNTINGTON'S DISEASE
TW202521119A (zh) * 2023-08-17 2025-06-01 美商紐羅克里生物科學有限公司 用於投與特定vmat2抑制劑之方法
WO2025038959A1 (en) * 2023-08-17 2025-02-20 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors
WO2025188830A1 (en) * 2024-03-06 2025-09-12 Neurocrine Biosciences, Inc. Methods for the administration of certain vmat2 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US952A (en) 1838-09-27 I antoni bengini
US10065A (en) 1853-10-04 Improvement in machines for topping cotton jn the field
FI3936130T3 (fi) * 2014-05-06 2024-04-23 Neurocrine Biosciences Inc Valbenatsiinin annostusohjelma hyperkineettisten liikehäiriöiden hoitoon
US20190015396A1 (en) * 2015-06-23 2019-01-17 Neurocrine Biosciences, Inc. Vmat2 inhibitors for treating neurological diseases or disorders
KR20230170136A (ko) * 2017-01-27 2023-12-18 뉴로크린 바이오사이언시즈 인코퍼레이티드 특정 vmat2 억제제의 투여 방법
WO2018164996A1 (en) * 2017-03-06 2018-09-13 Neurocrine Biosciences, Inc. Dosing regimen for valbenazine
SG11202100303QA (en) * 2018-08-15 2021-02-25 Neurocrine Biosciences Inc Methods for the administration of certain vmat2 inhibitors

Also Published As

Publication number Publication date
KR20220007105A (ko) 2022-01-18
JP2025013963A (ja) 2025-01-28
MA55893A (fr) 2022-03-16
MX2021013132A (es) 2021-11-25
CA3136466A1 (en) 2020-11-12
TWI850377B (zh) 2024-08-01
BR112021020709A2 (pt) 2021-12-14
JOP20210274A1 (ar) 2023-01-30
US20220040169A1 (en) 2022-02-10
AU2020270145A1 (en) 2021-12-23
SG11202111465RA (en) 2021-11-29
IL287902A (en) 2022-01-01
PH12021552745A1 (en) 2022-07-11
US20200397779A1 (en) 2020-12-24
EP3965764A1 (en) 2022-03-16
WO2020227672A1 (en) 2020-11-12
IL321020A (en) 2025-07-01
JP2022531696A (ja) 2022-07-08
AU2025256123A1 (en) 2025-11-13
TW202108138A (zh) 2021-03-01
CN114340624A (zh) 2022-04-12

Similar Documents

Publication Publication Date Title
JOP20210274A1 (ar) طرق لإعطاء مثبط vmat2 معين
JOP20200336A1 (ar) طرق إعطاء مثبطات vmat2 معينة
CY1126067T1 (el) Συντηγμενες πυρρολινες που δρουν σαν ειδικοι για ουβικιτινη αναστολεις πρωτεασης 30 (usp30)
JOP20220008A1 (ar) مثبطات parp1
JOP20220040A1 (ar) طرق لإعطاء مثبطات vmat2 معينة
AU2009303758A8 (en) Benzoquinoline inhibitors of vesicular monoamine transporter 2
MX2019008868A (es) Metodos para la administracion de ciertos inhibidores de proteina transportadora transportador de monoamina vesicular (vmat2).
CY1121853T1 (el) Συνδυαστικη θεραπεια για την αγωγη του διαβητη
CL2022001529A1 (es) Nuevos derivados de metilquinazolinona
NO20090835L (no) Nye HIV-reverstranskriptaseinhibitorer
EA202090932A1 (ru) Способы введения некоторых vmat2-ингибиторов
EA201691512A1 (ru) Бензохинолиновые ингибиторы везикулярного переносчика моноамина 2
NO20083836L (no) N-hydroksyakrylamidforbindelser
CL2022001353A1 (es) Inhibidores de egfr
DOP2022000076A (es) Inhibidores del factor d del complemento para administración oral
CO2025001287A2 (es) Inhibidores de la proteasa principal de sars-cov2
DOP2022000074A (es) Inhibidores del factor d del complemento para administración oral
AR087902A1 (es) COMPOSICIONES Y METODOS PARA TRATAR EL CANCER USANDO EL INHIBIDOR DE PI3Kb Y EL INHIBIDOR DE LA VIA DE MAPK, INCLUIDOS LOS INHIBIDORES DE MEK Y RAF
JOP20240183A1 (ar) مثبطات بروتين رابط لإموباميل واستخداماتها
DE50309647D1 (de) Ng fibrotischer erkrankungen
EA202190252A1 (ru) Способы введения определенных ингибиторов vmat2
CL2025001867A1 (es) Inhibición de la proteína transportadora de serotonina (5-htt)
AR133738A1 (es) Inhibidores de cdk2 y sus usos
AR128017A1 (es) Compuestos de pirazolopirazina como inhibidores de shp2
UY27911A1 (es) Nuevos profármacos de la (n-2-piridil-n-2-hifroxicarbonil-etil)-amida del ácido 1-metil-2-(4-amidinofenilaminometil)-benzimidazol-5-il-carboxílico, su preparación y su utilización como medicamentos