IL319998A - Method for producing compound having two-branched n-acetyl-d-galactosamine structure - Google Patents

Method for producing compound having two-branched n-acetyl-d-galactosamine structure

Info

Publication number
IL319998A
IL319998A IL319998A IL31999825A IL319998A IL 319998 A IL319998 A IL 319998A IL 319998 A IL319998 A IL 319998A IL 31999825 A IL31999825 A IL 31999825A IL 319998 A IL319998 A IL 319998A
Authority
IL
Israel
Prior art keywords
formula
compound represented
group
salt
chem
Prior art date
Application number
IL319998A
Other languages
English (en)
Hebrew (he)
Inventor
Hiroshi Nagasawa
Narumi Abe
Yoshio Nishi
Yuzo Abe
Takumi Kobayashi
Kohei SAKANISHI
Original Assignee
Daiichi Sankyo Co Ltd
Hiroshi Nagasawa
Narumi Abe
Yoshio Nishi
Yuzo Abe
Takumi Kobayashi
Kohei SAKANISHI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd, Hiroshi Nagasawa, Narumi Abe, Yoshio Nishi, Yuzo Abe, Takumi Kobayashi, Kohei SAKANISHI filed Critical Daiichi Sankyo Co Ltd
Publication of IL319998A publication Critical patent/IL319998A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00Processes for the preparation of sugar derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08Polyoxyalkylene derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
IL319998A 2022-10-05 2023-10-04 Method for producing compound having two-branched n-acetyl-d-galactosamine structure IL319998A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022161149 2022-10-05
PCT/JP2023/036159 WO2024075760A1 (ja) 2022-10-05 2023-10-04 2分岐型n-アセチル-d-ガラクトサミン構造を有する化合物の製造方法

Publications (1)

Publication Number Publication Date
IL319998A true IL319998A (en) 2025-06-01

Family

ID=90608068

Family Applications (1)

Application Number Title Priority Date Filing Date
IL319998A IL319998A (en) 2022-10-05 2023-10-04 Method for producing compound having two-branched n-acetyl-d-galactosamine structure

Country Status (7)

Country Link
EP (1) EP4600253A1 (https=)
JP (1) JPWO2024075760A1 (https=)
KR (1) KR20250078985A (https=)
CN (1) CN120129686A (https=)
IL (1) IL319998A (https=)
TW (1) TW202430499A (https=)
WO (1) WO2024075760A1 (https=)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102398295B1 (ko) 2018-03-09 2022-05-17 다이이찌 산쿄 가부시키가이샤 당원병 Ia형 치료약
MX2021014111A (es) * 2019-05-20 2021-12-10 Hoffmann La Roche Proceso para la preparacion de epimeros de fosforamidita de galnac.
IL291251B1 (en) 2019-09-10 2026-02-01 Daiichi Sankyo Co Ltd Oligonucleotide-galnac conjugate for targeted delivery to the liver and method for its production

Also Published As

Publication number Publication date
KR20250078985A (ko) 2025-06-04
WO2024075760A1 (ja) 2024-04-11
EP4600253A1 (en) 2025-08-13
JPWO2024075760A1 (https=) 2024-04-11
TW202430499A (zh) 2024-08-01
CN120129686A (zh) 2025-06-10

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