IL316075A - Crystalline form of lenifranor - Google Patents

Crystalline form of lenifranor

Info

Publication number
IL316075A
IL316075A IL316075A IL31607524A IL316075A IL 316075 A IL316075 A IL 316075A IL 316075 A IL316075 A IL 316075A IL 31607524 A IL31607524 A IL 31607524A IL 316075 A IL316075 A IL 316075A
Authority
IL
Israel
Prior art keywords
lanifibranor
crystalline form
crystalline
Prior art date
Application number
IL316075A
Other languages
English (en)
Hebrew (he)
Original Assignee
Inventiva
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inventiva filed Critical Inventiva
Publication of IL316075A publication Critical patent/IL316075A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
IL316075A 2022-04-05 2023-04-04 Crystalline form of lenifranor IL316075A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22305456 2022-04-05
PCT/EP2023/058743 WO2023194339A1 (en) 2022-04-05 2023-04-04 Crystalline form of lanifibranor

Publications (1)

Publication Number Publication Date
IL316075A true IL316075A (en) 2024-12-01

Family

ID=81326293

Family Applications (1)

Application Number Title Priority Date Filing Date
IL316075A IL316075A (en) 2022-04-05 2023-04-04 Crystalline form of lenifranor

Country Status (14)

Country Link
US (1) US20250243192A1 (https=)
EP (1) EP4504725A1 (https=)
JP (1) JP2025511847A (https=)
KR (1) KR20250002337A (https=)
CN (1) CN119301120A (https=)
AR (1) AR128985A1 (https=)
AU (1) AU2023250118A1 (https=)
CA (1) CA3247273A1 (https=)
IL (1) IL316075A (https=)
MX (1) MX2024012348A (https=)
PY (1) PY2324870A (https=)
TW (1) TW202404966A (https=)
UY (1) UY40216A (https=)
WO (1) WO2023194339A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240047402A (ko) * 2021-08-12 2024-04-12 크리스탈 파마슈티컬 (쑤저우) 씨오., 엘티디. 라니피브라노르의 결정형, 이의 제조 방법 및 이의 용도
CN120857930A (zh) 2023-01-19 2025-10-28 伊文蒂瓦公司 拉尼兰诺制剂
KR20260020956A (ko) 2023-06-05 2026-02-12 엥방티바 간 질환을 가진 환자의 내장 혈관 확장증의 치료에 사용하기 위한 라니피브라노르
WO2025061927A1 (en) * 2023-09-22 2025-03-27 Inventiva Method of making lanifibranor
WO2025132989A1 (en) 2023-12-21 2025-06-26 Inventiva Combination therapy for the prevention and/or the treatment of a liver disease
WO2025132955A1 (en) 2023-12-21 2025-06-26 Inventiva Combination therapy for the prevention and/or the treatment of a liver disease
TW202543596A (zh) 2024-03-15 2025-11-16 法商因文帝華公司 預防接受過氧化物酶體增生劑活化受體(ppar)促效劑治療患者之血液病症
WO2025191292A1 (en) 2024-03-15 2025-09-18 Inventiva Methods and monitoring of treatment with lanifibranor
WO2025238200A1 (en) 2024-05-17 2025-11-20 Inventiva Treatment of a liver disease in patients with hepatic impairment

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2890071B1 (fr) 2005-08-30 2007-11-09 Fournier Sa Sa Lab Nouveaux composes de l'indole
WO2022122014A1 (zh) 2020-12-11 2022-06-16 苏州科睿思制药有限公司 Lanifibranor的晶型及其制备方法和用途
WO2022143479A1 (zh) 2020-12-29 2022-07-07 广东东阳光药业有限公司 一种化合物的固体形式及其制备方法和用途
WO2022261410A1 (en) 2021-06-10 2022-12-15 Teva Pharmaceuticals International Gmbh Solid state forms of lanifibranor and process for preparation thereof
CN115466252A (zh) 2021-06-11 2022-12-13 上海希迈医药科技有限公司 一种Lanifibranor的晶型及其制备方法
KR20240047402A (ko) 2021-08-12 2024-04-12 크리스탈 파마슈티컬 (쑤저우) 씨오., 엘티디. 라니피브라노르의 결정형, 이의 제조 방법 및 이의 용도

Also Published As

Publication number Publication date
AU2023250118A1 (en) 2024-10-17
JP2025511847A (ja) 2025-04-16
KR20250002337A (ko) 2025-01-07
WO2023194339A1 (en) 2023-10-12
TW202404966A (zh) 2024-02-01
AR128985A1 (es) 2024-07-03
EP4504725A1 (en) 2025-02-12
CN119301120A (zh) 2025-01-10
MX2024012348A (es) 2024-11-08
PY2324870A (es) 2023-10-27
CA3247273A1 (en) 2023-10-12
UY40216A (es) 2023-10-31
US20250243192A1 (en) 2025-07-31

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