IL316014A - Adeno-associated virus vectors for delivering nucleic acids to retinal cells - Google Patents
Adeno-associated virus vectors for delivering nucleic acids to retinal cellsInfo
- Publication number
- IL316014A IL316014A IL316014A IL31601424A IL316014A IL 316014 A IL316014 A IL 316014A IL 316014 A IL316014 A IL 316014A IL 31601424 A IL31601424 A IL 31601424A IL 316014 A IL316014 A IL 316014A
- Authority
- IL
- Israel
- Prior art keywords
- adeno
- nucleic acid
- associated virus
- virus vectors
- acid delivery
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0075—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the delivery route, e.g. oral, subcutaneous
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14145—Special targeting system for viral vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263325550P | 2022-03-30 | 2022-03-30 | |
| US202263325540P | 2022-03-30 | 2022-03-30 | |
| US202263325543P | 2022-03-30 | 2022-03-30 | |
| US202263325559P | 2022-03-30 | 2022-03-30 | |
| US202263325553P | 2022-03-30 | 2022-03-30 | |
| US202263325551P | 2022-03-30 | 2022-03-30 | |
| US202263325558P | 2022-03-30 | 2022-03-30 | |
| US202263325542P | 2022-03-30 | 2022-03-30 | |
| US202263325544P | 2022-03-30 | 2022-03-30 | |
| US202263325555P | 2022-03-30 | 2022-03-30 | |
| US202263325548P | 2022-03-30 | 2022-03-30 | |
| US202263325562P | 2022-03-30 | 2022-03-30 | |
| US202263325541P | 2022-03-30 | 2022-03-30 | |
| PCT/US2023/016871 WO2023192463A2 (en) | 2022-03-30 | 2023-03-30 | Adeno-associated virus vectors for nucleic acid delivery to retinal cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL316014A true IL316014A (en) | 2024-11-01 |
Family
ID=88203541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL316014A IL316014A (en) | 2022-03-30 | 2023-03-30 | Adeno-associated virus vectors for delivering nucleic acids to retinal cells |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250327092A1 (OSRAM) |
| EP (1) | EP4499848A4 (OSRAM) |
| JP (1) | JP2025510975A (OSRAM) |
| KR (1) | KR20250006360A (OSRAM) |
| CN (1) | CN119213136A (OSRAM) |
| AU (1) | AU2023243048A1 (OSRAM) |
| CA (1) | CA3255255A1 (OSRAM) |
| IL (1) | IL316014A (OSRAM) |
| MX (1) | MX2024011963A (OSRAM) |
| TW (1) | TW202405180A (OSRAM) |
| WO (1) | WO2023192463A2 (OSRAM) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025072688A2 (en) * | 2023-09-27 | 2025-04-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Adeno-associated virus vectors for nucleic acid delivery to retinal cells, for nucleic acid delivery across retinal regions, or for nucleic acid delivery to retinal ganglion cells and/or retinal pigment epithelium cells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107012171B (zh) * | 2011-04-22 | 2021-07-13 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| CN118416088A (zh) * | 2017-03-03 | 2024-08-02 | 加利福尼亚大学董事会 | 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向 |
| EP3645052A4 (en) * | 2017-06-30 | 2021-07-28 | Regents of the University of California | ADENO-ASSOCIATED VIRUS VIRIONS WITH ASSOCIATED CAPSIDE VARIANTS AND METHODS OF USE |
| AU2019227910B2 (en) * | 2018-02-28 | 2025-07-17 | The Regents Of The University Of California | A modular system for gene and protein delivery based on AAV |
| US20220348613A1 (en) * | 2019-08-28 | 2022-11-03 | University of Pittsburgh - of the Commonwealath System of Higher Ecucation | Adeno-associated viruses and methods and materials for making and using adeno-associated viruses |
| MX2022002652A (es) * | 2019-09-09 | 2022-04-06 | Univ Pittsburgh Commonwealth Sys Higher Education | Metodos para restaurar la funcion lisosomal de celulas epiteliales de pigmento retiniano mediante activacion de tfeb. |
-
2023
- 2023-03-30 US US18/851,534 patent/US20250327092A1/en active Pending
- 2023-03-30 WO PCT/US2023/016871 patent/WO2023192463A2/en not_active Ceased
- 2023-03-30 JP JP2024557528A patent/JP2025510975A/ja active Pending
- 2023-03-30 TW TW112112171A patent/TW202405180A/zh unknown
- 2023-03-30 CN CN202380040951.9A patent/CN119213136A/zh active Pending
- 2023-03-30 IL IL316014A patent/IL316014A/en unknown
- 2023-03-30 EP EP23781800.0A patent/EP4499848A4/en active Pending
- 2023-03-30 AU AU2023243048A patent/AU2023243048A1/en active Pending
- 2023-03-30 CA CA3255255A patent/CA3255255A1/en active Pending
- 2023-03-30 KR KR1020247036295A patent/KR20250006360A/ko active Pending
-
2024
- 2024-09-27 MX MX2024011963A patent/MX2024011963A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4499848A2 (en) | 2025-02-05 |
| US20250327092A1 (en) | 2025-10-23 |
| KR20250006360A (ko) | 2025-01-10 |
| WO2023192463A2 (en) | 2023-10-05 |
| TW202405180A (zh) | 2024-02-01 |
| AU2023243048A1 (en) | 2024-10-03 |
| CN119213136A (zh) | 2024-12-27 |
| JP2025510975A (ja) | 2025-04-15 |
| MX2024011963A (es) | 2024-11-08 |
| CA3255255A1 (en) | 2023-10-05 |
| WO2023192463A3 (en) | 2023-12-21 |
| EP4499848A4 (en) | 2026-03-25 |
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