IL315423B1 - Ivusidnib forms and pharmaceutical preparations - Google Patents
Ivusidnib forms and pharmaceutical preparationsInfo
- Publication number
- IL315423B1 IL315423B1 IL315423A IL31542324A IL315423B1 IL 315423 B1 IL315423 B1 IL 315423B1 IL 315423 A IL315423 A IL 315423A IL 31542324 A IL31542324 A IL 31542324A IL 315423 B1 IL315423 B1 IL 315423B1
- Authority
- IL
- Israel
- Prior art keywords
- ivosidenib
- forms
- pharmaceutical compositions
- pharmaceutical
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862694596P | 2018-07-06 | 2018-07-06 | |
| PCT/US2019/040257 WO2020010058A1 (en) | 2018-07-06 | 2019-07-02 | Ivosidenib forms and pharmaceutical compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL315423A IL315423A (en) | 2024-11-01 |
| IL315423B1 true IL315423B1 (en) | 2026-04-01 |
Family
ID=69059942
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL315423A IL315423B1 (en) | 2018-07-06 | 2019-07-02 | Ivusidnib forms and pharmaceutical preparations |
| IL279877A IL279877A (en) | 2018-07-06 | 2020-12-30 | Ivosidenib forms and pharmaceutical compositions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL279877A IL279877A (en) | 2018-07-06 | 2020-12-30 | Ivosidenib forms and pharmaceutical compositions |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US12264148B2 (enExample) |
| EP (2) | EP3817744A4 (enExample) |
| JP (2) | JP7621242B2 (enExample) |
| KR (2) | KR102919157B1 (enExample) |
| CN (1) | CN112367995A (enExample) |
| AU (2) | AU2019299352B2 (enExample) |
| BR (1) | BR112021000156A2 (enExample) |
| CA (1) | CA3103498A1 (enExample) |
| EA (1) | EA202190217A1 (enExample) |
| IL (2) | IL315423B1 (enExample) |
| MA (1) | MA53099A (enExample) |
| MX (2) | MX2021000068A (enExample) |
| PH (1) | PH12021550017A1 (enExample) |
| SG (1) | SG11202012763TA (enExample) |
| TW (2) | TWI911130B (enExample) |
| UA (1) | UA129800C2 (enExample) |
| WO (1) | WO2020010058A1 (enExample) |
| ZA (1) | ZA202008034B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020327013B2 (en) | 2019-08-08 | 2026-03-26 | Les Laboratoires Servier | A method for preparing Ivosidenib and an intermediate thereof |
| GB201912411D0 (en) * | 2019-08-29 | 2019-10-16 | Johnson Matthey Plc | Crystalline forms of ivosidenib |
| AR133410A1 (es) | 2023-08-01 | 2025-09-24 | Servier Lab | Cocristal de un inhibidor de idh1, proceso de preparación del mismo, composiciones farmacéuticas del mismo, y métodos de tratamiento que implican el mismo |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9968595B2 (en) * | 2014-03-14 | 2018-05-15 | Agios Pharmaceuticals, Inc. | Pharmaceutical compositions of therapeutically active compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120121515A1 (en) | 2009-03-13 | 2012-05-17 | Lenny Dang | Methods and compositions for cell-proliferation-related disorders |
| WO2011050210A1 (en) | 2009-10-21 | 2011-04-28 | Agios Pharmaceuticals, Inc. | Methods and compositions for cell-proliferation-related disorders |
| RU2013144975A (ru) * | 2011-04-08 | 2015-05-20 | Пфайзер Инк. | Кристаллические и некристаллические формы тофацитиниба и фармацевтическая композиция, содержащая тофацитиниб, и усилитель проникновения |
| US9474779B2 (en) | 2012-01-19 | 2016-10-25 | Agios Pharmaceuticals, Inc. | Therapeutically active compositions and their methods of use |
| AR092439A1 (es) * | 2012-09-06 | 2015-04-22 | Bayer Healthcare Llc | Composicion farmaceutica recubierta que contiene regorafenib |
| MA39725B1 (fr) * | 2014-03-14 | 2021-09-30 | Les Laboratoires Servier Sas | Compositions pharmaceutiques de composés thérapeutiquement actifs |
| KR102699521B1 (ko) * | 2015-10-15 | 2024-08-26 | 르 라보레또레 쎄르비에르 | 악성 종양의 치료를 위한 조합물 요법 |
| MA43640A (fr) * | 2016-02-26 | 2018-11-28 | Agios Pharmaceuticals Inc | Inhibiteurs de idh1 pour le traitement de cancers hématologiques et de tumeurs solides |
| US11066390B2 (en) | 2017-11-27 | 2021-07-20 | Assia Chemical Industries Ltd. | Solid state forms of Ivosidenib |
-
2019
- 2019-07-02 EA EA202190217A patent/EA202190217A1/ru unknown
- 2019-07-02 CN CN201980045552.5A patent/CN112367995A/zh active Pending
- 2019-07-02 EP EP19829932.3A patent/EP3817744A4/en not_active Withdrawn
- 2019-07-02 IL IL315423A patent/IL315423B1/en unknown
- 2019-07-02 JP JP2021500178A patent/JP7621242B2/ja active Active
- 2019-07-02 KR KR1020217000885A patent/KR102919157B1/ko active Active
- 2019-07-02 UA UAA202100436A patent/UA129800C2/uk unknown
- 2019-07-02 CA CA3103498A patent/CA3103498A1/en active Pending
- 2019-07-02 BR BR112021000156-5A patent/BR112021000156A2/pt unknown
- 2019-07-02 EP EP25187804.7A patent/EP4603147A3/en active Pending
- 2019-07-02 MX MX2021000068A patent/MX2021000068A/es unknown
- 2019-07-02 US US17/258,102 patent/US12264148B2/en active Active
- 2019-07-02 SG SG11202012763TA patent/SG11202012763TA/en unknown
- 2019-07-02 WO PCT/US2019/040257 patent/WO2020010058A1/en not_active Ceased
- 2019-07-02 AU AU2019299352A patent/AU2019299352B2/en active Active
- 2019-07-02 KR KR1020257038241A patent/KR20250164882A/ko active Pending
- 2019-07-02 MA MA053099A patent/MA53099A/fr unknown
- 2019-07-05 TW TW114126745A patent/TWI911130B/zh active
- 2019-07-05 TW TW108123796A patent/TWI902665B/zh active
-
2020
- 2020-12-22 ZA ZA2020/08034A patent/ZA202008034B/en unknown
- 2020-12-30 IL IL279877A patent/IL279877A/en unknown
-
2021
- 2021-01-04 PH PH12021550017A patent/PH12021550017A1/en unknown
- 2021-01-06 MX MX2023011687A patent/MX2023011687A/es unknown
-
2024
- 2024-08-08 JP JP2024131926A patent/JP2024150784A/ja not_active Withdrawn
-
2025
- 2025-05-23 AU AU2025203835A patent/AU2025203835A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9968595B2 (en) * | 2014-03-14 | 2018-05-15 | Agios Pharmaceuticals, Inc. | Pharmaceutical compositions of therapeutically active compounds |
Non-Patent Citations (1)
| Title |
|---|
| MINOR CAIRA ED - MONTCHAMP JEAN-LUC, CRYSTALLINE POLYMORPHISM OF ORGANIC COMPOUNDS, 1 January 1998 (1998-01-01) * |
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