MX2021000068A - Formas y composiciones farmaceuticas de ivosidenib. - Google Patents

Formas y composiciones farmaceuticas de ivosidenib.

Info

Publication number
MX2021000068A
MX2021000068A MX2021000068A MX2021000068A MX2021000068A MX 2021000068 A MX2021000068 A MX 2021000068A MX 2021000068 A MX2021000068 A MX 2021000068A MX 2021000068 A MX2021000068 A MX 2021000068A MX 2021000068 A MX2021000068 A MX 2021000068A
Authority
MX
Mexico
Prior art keywords
ivosidenib
forms
pharmaceutical compositions
formulations
further provided
Prior art date
Application number
MX2021000068A
Other languages
English (en)
Spanish (es)
Inventor
Shijie Zhang
Chong - Hui Gu
Jacob Paul Sizemore
Original Assignee
Agios Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agios Pharmaceuticals Inc filed Critical Agios Pharmaceuticals Inc
Publication of MX2021000068A publication Critical patent/MX2021000068A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2021000068A 2018-07-06 2019-07-02 Formas y composiciones farmaceuticas de ivosidenib. MX2021000068A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862694596P 2018-07-06 2018-07-06
PCT/US2019/040257 WO2020010058A1 (en) 2018-07-06 2019-07-02 Ivosidenib forms and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
MX2021000068A true MX2021000068A (es) 2021-03-25

Family

ID=69059942

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2021000068A MX2021000068A (es) 2018-07-06 2019-07-02 Formas y composiciones farmaceuticas de ivosidenib.
MX2023011687A MX2023011687A (es) 2018-07-06 2021-01-06 Formas y composiciones farmaceuticas de ivosidenib.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2023011687A MX2023011687A (es) 2018-07-06 2021-01-06 Formas y composiciones farmaceuticas de ivosidenib.

Country Status (18)

Country Link
US (1) US12264148B2 (enExample)
EP (2) EP3817744A4 (enExample)
JP (2) JP7621242B2 (enExample)
KR (2) KR102919157B1 (enExample)
CN (1) CN112367995A (enExample)
AU (2) AU2019299352B2 (enExample)
BR (1) BR112021000156A2 (enExample)
CA (1) CA3103498A1 (enExample)
EA (1) EA202190217A1 (enExample)
IL (2) IL315423B1 (enExample)
MA (1) MA53099A (enExample)
MX (2) MX2021000068A (enExample)
PH (1) PH12021550017A1 (enExample)
SG (1) SG11202012763TA (enExample)
TW (2) TWI911130B (enExample)
UA (1) UA129800C2 (enExample)
WO (1) WO2020010058A1 (enExample)
ZA (1) ZA202008034B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020327013B2 (en) 2019-08-08 2026-03-26 Les Laboratoires Servier A method for preparing Ivosidenib and an intermediate thereof
GB201912411D0 (en) * 2019-08-29 2019-10-16 Johnson Matthey Plc Crystalline forms of ivosidenib
AR133410A1 (es) 2023-08-01 2025-09-24 Servier Lab Cocristal de un inhibidor de idh1, proceso de preparación del mismo, composiciones farmacéuticas del mismo, y métodos de tratamiento que implican el mismo

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120121515A1 (en) 2009-03-13 2012-05-17 Lenny Dang Methods and compositions for cell-proliferation-related disorders
WO2011050210A1 (en) 2009-10-21 2011-04-28 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
RU2013144975A (ru) * 2011-04-08 2015-05-20 Пфайзер Инк. Кристаллические и некристаллические формы тофацитиниба и фармацевтическая композиция, содержащая тофацитиниб, и усилитель проникновения
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
AR092439A1 (es) * 2012-09-06 2015-04-22 Bayer Healthcare Llc Composicion farmaceutica recubierta que contiene regorafenib
MA39725B1 (fr) * 2014-03-14 2021-09-30 Les Laboratoires Servier Sas Compositions pharmaceutiques de composés thérapeutiquement actifs
NZ723859A (en) * 2014-03-14 2023-01-27 Servier Lab Pharmaceutical compositions of therapeutically active compounds and their uses
KR102699521B1 (ko) * 2015-10-15 2024-08-26 르 라보레또레 쎄르비에르 악성 종양의 치료를 위한 조합물 요법
MA43640A (fr) * 2016-02-26 2018-11-28 Agios Pharmaceuticals Inc Inhibiteurs de idh1 pour le traitement de cancers hématologiques et de tumeurs solides
US11066390B2 (en) 2017-11-27 2021-07-20 Assia Chemical Industries Ltd. Solid state forms of Ivosidenib

Also Published As

Publication number Publication date
UA129800C2 (uk) 2025-08-06
TWI911130B (zh) 2026-01-01
EP3817744A1 (en) 2021-05-12
MA53099A (fr) 2021-05-12
CA3103498A1 (en) 2020-01-09
AU2019299352A1 (en) 2021-01-07
ZA202008034B (en) 2021-10-27
KR102919157B1 (ko) 2026-01-27
US20210323944A1 (en) 2021-10-21
TW202019419A (zh) 2020-06-01
IL315423B1 (en) 2026-04-01
TWI902665B (zh) 2025-11-01
TW202543623A (zh) 2025-11-16
AU2019299352B2 (en) 2025-02-27
KR20210029775A (ko) 2021-03-16
PH12021550017A1 (en) 2021-09-13
EP3817744A4 (en) 2022-07-13
JP2024150784A (ja) 2024-10-23
MX2023011687A (es) 2023-10-19
EP4603147A3 (en) 2025-10-01
IL279877A (en) 2021-03-01
AU2025203835A1 (en) 2025-06-12
JP2021529805A (ja) 2021-11-04
CN112367995A (zh) 2021-02-12
SG11202012763TA (en) 2021-02-25
JP7621242B2 (ja) 2025-01-24
BR112021000156A2 (pt) 2021-04-06
WO2020010058A1 (en) 2020-01-09
US12264148B2 (en) 2025-04-01
EA202190217A1 (ru) 2021-04-16
IL315423A (en) 2024-11-01
EP4603147A2 (en) 2025-08-20
KR20250164882A (ko) 2025-11-25

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