IL314226A - Designed cytokine compositions and methods of use - Google Patents

Designed cytokine compositions and methods of use

Info

Publication number
IL314226A
IL314226A IL314226A IL31422624A IL314226A IL 314226 A IL314226 A IL 314226A IL 314226 A IL314226 A IL 314226A IL 31422624 A IL31422624 A IL 31422624A IL 314226 A IL314226 A IL 314226A
Authority
IL
Israel
Prior art keywords
methods
cytokine compositions
designed
designed cytokine
compositions
Prior art date
Application number
IL314226A
Other languages
English (en)
Hebrew (he)
Original Assignee
Outpace Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Outpace Bio Inc filed Critical Outpace Bio Inc
Publication of IL314226A publication Critical patent/IL314226A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5443IL-15
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL314226A 2022-01-11 2023-01-11 Designed cytokine compositions and methods of use IL314226A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263298623P 2022-01-11 2022-01-11
US202363479178P 2023-01-09 2023-01-09
US202363479177P 2023-01-09 2023-01-09
US202363479176P 2023-01-09 2023-01-09
PCT/US2023/060508 WO2023137346A2 (en) 2022-01-11 2023-01-11 Designed cytokine compositions and methods of use

Publications (1)

Publication Number Publication Date
IL314226A true IL314226A (en) 2024-09-01

Family

ID=87279672

Family Applications (1)

Application Number Title Priority Date Filing Date
IL314226A IL314226A (en) 2022-01-11 2023-01-11 Designed cytokine compositions and methods of use

Country Status (10)

Country Link
US (1) US20250223330A1 (https=)
EP (1) EP4463469A4 (https=)
JP (1) JP2025502205A (https=)
KR (1) KR20240164594A (https=)
CN (1) CN119053616A (https=)
AU (1) AU2023208031A1 (https=)
CA (1) CA3248134A1 (https=)
IL (1) IL314226A (https=)
MX (1) MX2024008642A (https=)
WO (1) WO2023137346A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL325764A (en) * 2023-07-13 2026-03-01 Outpace Bio Inc Designed compositions of interleukin-2 cytokine and methods of use
WO2025212606A1 (en) * 2024-04-01 2025-10-09 Bio-Techne Corporation Synthetic il-2 polypeptides and conjugates, compositions, and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210025522A (ko) * 2018-06-25 2021-03-09 유니버시티 오브 워싱톤 강력하고 선택적인 인터루킨 모방체의 드 노보 디자인
MX2021000801A (es) * 2018-07-24 2021-04-12 BioNTech SE Agonistas de il2.
CN118510795A (zh) * 2022-01-07 2024-08-16 苏州克睿基因生物科技有限公司 新型白介素-2多肽

Also Published As

Publication number Publication date
US20250223330A1 (en) 2025-07-10
KR20240164594A (ko) 2024-11-19
CA3248134A1 (en) 2023-07-20
MX2024008642A (es) 2024-09-23
EP4463469A2 (en) 2024-11-20
AU2023208031A1 (en) 2024-08-29
EP4463469A4 (en) 2026-01-14
WO2023137346A2 (en) 2023-07-20
JP2025502205A (ja) 2025-01-24
CN119053616A (zh) 2024-11-29
WO2023137346A3 (en) 2023-11-16

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