IL314205A - Ramibrutinib for use in the treatment of hidradenitis suppurativa - Google Patents

Ramibrutinib for use in the treatment of hidradenitis suppurativa

Info

Publication number
IL314205A
IL314205A IL314205A IL31420524A IL314205A IL 314205 A IL314205 A IL 314205A IL 314205 A IL314205 A IL 314205A IL 31420524 A IL31420524 A IL 31420524A IL 314205 A IL314205 A IL 314205A
Authority
IL
Israel
Prior art keywords
remibrutinib
treatment
hidradenitis suppurativa
suppurativa
hidradenitis
Prior art date
Application number
IL314205A
Other languages
English (en)
Hebrew (he)
Inventor
Souvik Bhattacharya
Bruno Bieth
Bruno Cenni
Gordon Graham
Michael Juhnke
Christian Loesche
Karin Rapp
Kim-Hien Sin
Jonas Benjamin Zierer
Original Assignee
Novartis Ag
Souvik Bhattacharya
Bruno Bieth
Bruno Cenni
Gordon Graham
Michael Juhnke
Christian Loesche
Karin Rapp
Sin Kim Hien
Jonas Benjamin Zierer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Souvik Bhattacharya, Bruno Bieth, Bruno Cenni, Gordon Graham, Michael Juhnke, Christian Loesche, Karin Rapp, Sin Kim Hien, Jonas Benjamin Zierer filed Critical Novartis Ag
Publication of IL314205A publication Critical patent/IL314205A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL314205A 2022-02-28 2023-02-27 Ramibrutinib for use in the treatment of hidradenitis suppurativa IL314205A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263314572P 2022-02-28 2022-02-28
US202263369016P 2022-07-21 2022-07-21
PCT/IB2023/051787 WO2023161887A1 (en) 2022-02-28 2023-02-27 Remibrutinib for use in the treatment of hidradenitis suppurativa

Publications (1)

Publication Number Publication Date
IL314205A true IL314205A (en) 2024-09-01

Family

ID=85570288

Family Applications (1)

Application Number Title Priority Date Filing Date
IL314205A IL314205A (en) 2022-02-28 2023-02-27 Ramibrutinib for use in the treatment of hidradenitis suppurativa

Country Status (11)

Country Link
US (1) US20250099465A1 (https=)
EP (1) EP4486346A1 (https=)
JP (2) JP7696006B2 (https=)
KR (1) KR20240155278A (https=)
CN (1) CN120617264A (https=)
AU (1) AU2023225222A1 (https=)
CA (1) CA3251002A1 (https=)
IL (1) IL314205A (https=)
MX (1) MX2024010392A (https=)
TW (1) TW202342048A (https=)
WO (1) WO2023161887A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250243170A1 (en) * 2024-01-26 2025-07-31 Novartis Ag Remibrutinib drug substance and drug product substantially free of nitrosamine impurity

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3425B1 (ar) 2013-07-15 2019-10-20 Novartis Ag مشتقات البابيريدينيل-اندول واستخدامها كعامل متمم لمثبطات b
US9512084B2 (en) 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
LT3380465T (lt) 2015-11-26 2020-11-10 Novartis Ag Diamino piridino dariniai
JOP20190053A1 (ar) 2016-09-23 2019-03-21 Novartis Ag مركبات أزا إندازول للاستخدام في إصابات الأوتار و/ أو الرباط
JP7007374B2 (ja) 2016-09-23 2022-01-24 ノバルティス アーゲー 腱及び/又は靭帯損傷に使用するためのインダゾール化合物
CN112512527A (zh) * 2018-09-12 2021-03-16 杭州索元生物医药股份有限公司 恩扎妥林和btk抑制剂的组合及其用途
MX2021014161A (es) 2019-05-23 2022-01-04 Novartis Ag Metodos de tratamiento del sindrome de sjogren utilizando un inhibidor de la tirosina quinasa de bruton.
HRP20251001T1 (hr) 2019-05-23 2025-10-24 Novartis Ag Inhibitor brutonove tirozin kinaze za upotrebu u liječenju kronične spontane urtikarije
BR112021023054A2 (pt) * 2019-05-23 2022-03-29 Novartis Ag Formas cristalinas de um inibidor de btk
TW202142237A (zh) * 2020-01-08 2021-11-16 美商普林斯匹亞生物製藥公司 包含2-[3-[4-胺基-3-(2-氟-4-苯氧基-苯基)-1h-吡唑并[3,4-d]嘧啶-1-基]哌啶-1-羰基]-4,4-二甲基戊-2-烯腈之局部醫藥組成物
TWI905371B (zh) 2021-01-26 2025-11-21 瑞士商諾華公司 藥物組成物

Also Published As

Publication number Publication date
EP4486346A1 (en) 2025-01-08
JP2024511938A (ja) 2024-03-18
JP7696006B2 (ja) 2025-06-19
WO2023161887A1 (en) 2023-08-31
TW202342048A (zh) 2023-11-01
CA3251002A1 (en) 2023-08-31
MX2024010392A (es) 2024-09-06
US20250099465A1 (en) 2025-03-27
KR20240155278A (ko) 2024-10-28
AU2023225222A1 (en) 2024-07-25
JP2025134747A (ja) 2025-09-17
CN120617264A (zh) 2025-09-12

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