IL313999A - Deuterated organic compounds and uses thereof - Google Patents
Deuterated organic compounds and uses thereofInfo
- Publication number
- IL313999A IL313999A IL313999A IL31399924A IL313999A IL 313999 A IL313999 A IL 313999A IL 313999 A IL313999 A IL 313999A IL 31399924 A IL31399924 A IL 31399924A IL 313999 A IL313999 A IL 313999A
- Authority
- IL
- Israel
- Prior art keywords
- organic compounds
- deuterated organic
- deuterated
- compounds
- organic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263296137P | 2022-01-03 | 2022-01-03 | |
| US202263314466P | 2022-02-27 | 2022-02-27 | |
| US202263345002P | 2022-05-23 | 2022-05-23 | |
| US202263394565P | 2022-08-02 | 2022-08-02 | |
| US202263384988P | 2022-11-25 | 2022-11-25 | |
| PCT/US2023/010055 WO2023130119A1 (en) | 2022-01-03 | 2023-01-03 | Deuterated organic compounds and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL313999A true IL313999A (en) | 2024-08-01 |
Family
ID=87000385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL313999A IL313999A (en) | 2022-01-03 | 2023-01-03 | Deuterated organic compounds and uses thereof |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US12606523B2 (https=) |
| EP (1) | EP4460292A4 (https=) |
| JP (1) | JP2025501411A (https=) |
| KR (1) | KR20240132477A (https=) |
| AU (1) | AU2023204433A1 (https=) |
| CA (1) | CA3242755A1 (https=) |
| IL (1) | IL313999A (https=) |
| MX (1) | MX2024008371A (https=) |
| TW (1) | TW202333671A (https=) |
| WO (1) | WO2023130119A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW202517609A (zh) | 2023-07-02 | 2025-05-01 | 美商英格瑞治療公司 | 氘化有機化合物及其用途(二) |
| WO2026011157A1 (en) | 2024-07-05 | 2026-01-08 | Engrail Therapeutics, Inc. | Crystalline forms |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4197243A (en) * | 1975-04-02 | 1980-04-08 | Yamanouchi Pharmaceutical Co., Ltd. | N-1-Benzyl-3-pyrrolidinyl-4-dimethylamino benzamide derivatives |
| US4210660A (en) | 1978-12-20 | 1980-07-01 | Yamanouchi Pharmaceutical Co., Ltd. | Benzamide derivatives |
| TW212139B (https=) | 1991-04-15 | 1993-09-01 | Yamanouchi Pharma Co Ltd | |
| SK281042B6 (sk) | 1992-09-18 | 2000-11-07 | Yamanouchi Pharmaceutical Co., Ltd | Prípravok hydrogélového typu s ustáleným uvoľňovaním |
| EP0667867A1 (en) | 1992-11-05 | 1995-08-23 | Smithkline Beecham Plc | Piperidine derivatives as 5-ht4 receptor antagonists |
| US6872405B2 (en) | 2001-05-10 | 2005-03-29 | Yamanouchi Pharmaceutical Co., Ltd. | Quick-disintegrating tablet in buccal cavity and manufacturing method thereof |
| KR102373288B1 (ko) | 2013-12-03 | 2022-03-10 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
| CN104744333A (zh) | 2013-12-26 | 2015-07-01 | 张云 | 一种奈莫必利的生产方法 |
| US20190343827A1 (en) | 2018-05-08 | 2019-11-14 | Izumi Technology, Llc | Deuterated analogs of tariquidar |
| MX2021010198A (es) | 2019-02-27 | 2021-09-21 | Univ California | Indoles n-sustituidos y otros heterociclos para el tratamiento de trastornos cerebrales. |
| US20210017160A1 (en) | 2019-07-16 | 2021-01-21 | Cyclerion Therapeutics, Inc. | DEUTERATED sGC STIMULATORS |
| TW202340145A (zh) | 2022-01-03 | 2023-10-16 | 美商恩格瑞爾療法公司 | 氘化有機化合物及其用途 |
| TW202517609A (zh) | 2023-07-02 | 2025-05-01 | 美商英格瑞治療公司 | 氘化有機化合物及其用途(二) |
-
2023
- 2023-01-03 TW TW112100105A patent/TW202333671A/zh unknown
- 2023-01-03 KR KR1020247025930A patent/KR20240132477A/ko active Pending
- 2023-01-03 JP JP2024561731A patent/JP2025501411A/ja active Pending
- 2023-01-03 WO PCT/US2023/010055 patent/WO2023130119A1/en not_active Ceased
- 2023-01-03 AU AU2023204433A patent/AU2023204433A1/en active Pending
- 2023-01-03 EP EP23735189.5A patent/EP4460292A4/en active Pending
- 2023-01-03 CA CA3242755A patent/CA3242755A1/en active Pending
- 2023-01-03 IL IL313999A patent/IL313999A/en unknown
-
2024
- 2024-07-02 MX MX2024008371A patent/MX2024008371A/es unknown
- 2024-07-03 US US18/763,819 patent/US12606523B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023130119A1 (en) | 2023-07-06 |
| US20250011280A1 (en) | 2025-01-09 |
| KR20240132477A (ko) | 2024-09-03 |
| EP4460292A1 (en) | 2024-11-13 |
| CA3242755A1 (en) | 2023-07-06 |
| MX2024008371A (es) | 2024-12-06 |
| JP2025501411A (ja) | 2025-01-17 |
| TW202333671A (zh) | 2023-09-01 |
| EP4460292A4 (en) | 2025-07-16 |
| US12606523B2 (en) | 2026-04-21 |
| AU2023204433A1 (en) | 2024-07-18 |
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