IL312623A - Preserved formulations - Google Patents

Preserved formulations

Info

Publication number
IL312623A
IL312623A IL312623A IL31262324A IL312623A IL 312623 A IL312623 A IL 312623A IL 312623 A IL312623 A IL 312623A IL 31262324 A IL31262324 A IL 31262324A IL 312623 A IL312623 A IL 312623A
Authority
IL
Israel
Prior art keywords
composition
concentration
bif
phosphate
group
Prior art date
Application number
IL312623A
Other languages
English (en)
Hebrew (he)
Inventor
David Paul Allen
John Michael Beals
Vincent John Corvari
Patrick Daniel Donovan
Ken Kangyi Qian
Wei Wang
Original Assignee
Lilly Co Eli
David Paul Allen
John Michael Beals
Vincent John Corvari
Patrick Daniel Donovan
Ken Kangyi Qian
Wei Wang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, David Paul Allen, John Michael Beals, Vincent John Corvari, Patrick Daniel Donovan, Ken Kangyi Qian, Wei Wang filed Critical Lilly Co Eli
Publication of IL312623A publication Critical patent/IL312623A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL312623A 2021-11-15 2022-11-14 Preserved formulations IL312623A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163279390P 2021-11-15 2021-11-15
PCT/US2022/079791 WO2023086980A1 (en) 2021-11-15 2022-11-14 Preserved formulations

Publications (1)

Publication Number Publication Date
IL312623A true IL312623A (en) 2024-07-01

Family

ID=84537390

Family Applications (1)

Application Number Title Priority Date Filing Date
IL312623A IL312623A (en) 2021-11-15 2022-11-14 Preserved formulations

Country Status (19)

Country Link
US (1) US20250000950A1 (https=)
EP (1) EP4433024A1 (https=)
JP (1) JP2024543457A (https=)
KR (1) KR20240082407A (https=)
CN (1) CN118302152A (https=)
AR (1) AR127619A1 (https=)
AU (1) AU2022386352B2 (https=)
CA (1) CA3238180A1 (https=)
CL (1) CL2024001415A1 (https=)
CO (1) CO2024006121A2 (https=)
CR (1) CR20240202A (https=)
DO (1) DOP2024000084A (https=)
EC (1) ECSP24036789A (https=)
IL (1) IL312623A (https=)
JO (1) JOP20240108A1 (https=)
MX (1) MX2024005879A (https=)
PE (1) PE20241354A1 (https=)
TW (1) TWI871539B (https=)
WO (1) WO2023086980A1 (https=)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8097584B2 (en) * 2005-05-25 2012-01-17 Novo Nordisk A/S Stabilized formulations of insulin that comprise ethylenediamine
AR081066A1 (es) 2010-04-02 2012-06-06 Hanmi Holdings Co Ltd Conjugado de insulina donde se usa un fragmento de inmunoglobulina
US20130011378A1 (en) * 2011-06-17 2013-01-10 Tzung-Horng Yang Stable formulations of a hyaluronan-degrading enzyme
CN103509118B (zh) 2012-06-15 2016-03-23 郭怀祖 胰岛素-Fc融合蛋白
AR091902A1 (es) * 2012-07-25 2015-03-11 Hanmi Pharm Ind Co Ltd Formulacion liquida de un conjugado de insulina de accion prolongada
AR105616A1 (es) * 2015-05-07 2017-10-25 Lilly Co Eli Proteínas de fusión
JP2020513019A (ja) 2017-04-05 2020-04-30 ノヴォ ノルディスク アー/エス オリゴマー伸長インスリン−Fcコンジュゲート
KR20210029210A (ko) 2018-06-29 2021-03-15 악스톤 바이오사이언시스 코퍼레이션 초장기 작용 인슐린-fc 융합 단백질 및 사용 방법
WO2020074544A1 (en) 2018-10-10 2020-04-16 Novo Nordisk A/S Oligomer extended insulin-fc conjugates and their medical use
US20220354782A1 (en) * 2019-09-17 2022-11-10 Cass Pharmaceuticals, Inc. Subcutaneously injectable insulin and glucagon formulations and methods of administration
WO2021119607A1 (en) * 2019-12-13 2021-06-17 The Board Of Trustees Of The Leland Stanford Junior University Stable monomeric insulin formulations enabled by supramolecular pegylation of insulin analogues
KR20250142943A (ko) 2019-12-19 2025-09-30 악스톤 바이오사이언시스 코퍼레이션 초-장기 작용 인슐린-fc 융합 단백질 및 사용 방법
US11186623B2 (en) 2019-12-24 2021-11-30 Akston Bioscience Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
US11192930B2 (en) 2020-04-10 2021-12-07 Askton Bioscences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
US11198719B2 (en) 2020-04-29 2021-12-14 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use

Also Published As

Publication number Publication date
TW202339790A (zh) 2023-10-16
JOP20240108A1 (ar) 2024-05-14
KR20240082407A (ko) 2024-06-10
ECSP24036789A (es) 2024-06-28
PE20241354A1 (es) 2024-07-03
MX2024005879A (es) 2024-05-29
CR20240202A (es) 2024-06-11
CL2024001415A1 (es) 2024-10-18
CN118302152A (zh) 2024-07-05
DOP2024000084A (es) 2024-06-16
EP4433024A1 (en) 2024-09-25
AU2022386352A1 (en) 2024-05-09
AR127619A1 (es) 2024-02-14
JP2024543457A (ja) 2024-11-21
US20250000950A1 (en) 2025-01-02
WO2023086980A1 (en) 2023-05-19
CO2024006121A2 (es) 2024-06-27
AU2022386352B2 (en) 2025-12-18
TWI871539B (zh) 2025-02-01
CA3238180A1 (en) 2023-05-19

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