IL310378A - Serotonin receptor agonists that cause hallucinations and that do not cause hallucinations and methods for their preparation and use - Google Patents
Serotonin receptor agonists that cause hallucinations and that do not cause hallucinations and methods for their preparation and useInfo
- Publication number
- IL310378A IL310378A IL310378A IL31037824A IL310378A IL 310378 A IL310378 A IL 310378A IL 310378 A IL310378 A IL 310378A IL 31037824 A IL31037824 A IL 31037824A IL 310378 A IL310378 A IL 310378A
- Authority
- IL
- Israel
- Prior art keywords
- hallucinogenic
- making
- methods
- same
- receptor agonists
- Prior art date
Links
- 230000003400 hallucinatory effect Effects 0.000 title 2
- 239000000952 serotonin receptor agonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D345/00—Heterocyclic compounds containing rings having selenium or tellurium atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163232548P | 2021-08-12 | 2021-08-12 | |
| US202163232614P | 2021-08-12 | 2021-08-12 | |
| US202163232539P | 2021-08-12 | 2021-08-12 | |
| US202163238135P | 2021-08-28 | 2021-08-28 | |
| US202163238134P | 2021-08-28 | 2021-08-28 | |
| US202163238132P | 2021-08-28 | 2021-08-28 | |
| US202163238133P | 2021-08-28 | 2021-08-28 | |
| US202163239965P | 2021-09-02 | 2021-09-02 | |
| US202163239964P | 2021-09-02 | 2021-09-02 | |
| US202163239963P | 2021-09-02 | 2021-09-02 | |
| US202163285656P | 2021-12-03 | 2021-12-03 | |
| US202163285688P | 2021-12-03 | 2021-12-03 | |
| US202163285679P | 2021-12-03 | 2021-12-03 | |
| US202163292567P | 2021-12-22 | 2021-12-22 | |
| US202263301196P | 2022-01-20 | 2022-01-20 | |
| US202263314379P | 2022-02-26 | 2022-02-26 | |
| US202263314378P | 2022-02-26 | 2022-02-26 | |
| US202263314377P | 2022-02-26 | 2022-02-26 | |
| US202263319200P | 2022-03-11 | 2022-03-11 | |
| US202263325515P | 2022-03-30 | 2022-03-30 | |
| PCT/US2022/040048 WO2023018864A1 (en) | 2021-08-12 | 2022-08-11 | Hallucinogenic and non-hallucinogenic serotonin receptor agonists and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL310378A true IL310378A (en) | 2024-03-01 |
Family
ID=85201052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL310378A IL310378A (en) | 2021-08-12 | 2022-08-11 | Serotonin receptor agonists that cause hallucinations and that do not cause hallucinations and methods for their preparation and use |
Country Status (8)
| Country | Link |
|---|---|
| US (8) | US11780807B2 (https=) |
| EP (1) | EP4384172A4 (https=) |
| JP (1) | JP2024531229A (https=) |
| KR (1) | KR20240058859A (https=) |
| AU (1) | AU2022328217A1 (https=) |
| CA (1) | CA3229044A1 (https=) |
| IL (1) | IL310378A (https=) |
| WO (1) | WO2023018864A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3519816A4 (en) | 2016-09-29 | 2020-05-06 | The Regents of the University of California | CONNECTIONS FOR INCREASING NEURONAL PLASTICITY |
| KR102946120B1 (ko) | 2019-02-27 | 2026-03-30 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클 |
| EP4255422A4 (en) * | 2020-12-03 | 2024-12-18 | Mydecine Innovations Group Inc. | NEW PSILOCIN ANALOGUE COMPOSITIONS AND METHODS OF THEIR SYNTHESIS |
| JP2024520485A (ja) * | 2021-05-26 | 2024-05-24 | ブライト マインズ バイオサイエンスィズ インコーポレイテッド | 複素環式化合物及びその調製方法 |
| KR20240058859A (ko) | 2021-08-12 | 2024-05-03 | 쿨레온 엘엘씨 | 환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 |
| IL313455A (en) | 2021-12-15 | 2024-08-01 | Delix Therapeutics Inc | Phenoxy and benzyloxy modified psychroplastogens and their uses |
| CN118974044A (zh) | 2021-12-24 | 2024-11-15 | 赛洛私人有限公司 | 化合物 |
| WO2023173196A1 (en) | 2022-03-18 | 2023-09-21 | Enveric Biosciences Canada Inc. | C4-carboxylic acid-substituted tryptamine derivatives and methods of using |
| AU2023234202A1 (en) * | 2022-03-18 | 2024-11-07 | Enveric Biosciences Canada Inc. | Salts of c4-carboxylic acid- and c4-carbonothioate-substituted tryptamine derivatives and methods of using |
| WO2024229454A2 (en) * | 2023-05-04 | 2024-11-07 | Gilgamesh Pharmaceuticals, Inc. | Novel ergolines and methods of treating mood disorders |
| WO2025000051A1 (en) | 2023-06-28 | 2025-01-02 | Psylo Pty Ltd | Pyrrolopyridine compounds for the treatment of mental illnesses |
| WO2025000053A1 (en) | 2023-06-28 | 2025-01-02 | Psylo Pty Ltd | Compounds |
| WO2025042885A1 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Salts and solid forms of benzothiophene and benzoselenophene serotonin receptor modulators |
| WO2025049510A1 (en) * | 2023-08-29 | 2025-03-06 | Caamtech, Inc. | 4-hydroxy-n-ethyltryptamine |
| WO2025122513A1 (en) * | 2023-12-04 | 2025-06-12 | Delix Therapeutics, Inc. | Methods of treating neuropsychiatric disorders with non-hallucinogenic tryptamines |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US3636218A (en) | 1969-10-22 | 1972-01-18 | Colgate Palmolive Co | Pharmaceutical compositions and methods containing 1 2 3 4-tetrahydrobenzothieno(2 3-c)pyridines |
| US4137414A (en) | 1977-09-26 | 1979-01-30 | G. D. Searle & Co. | 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds |
| EP0204349A3 (de) | 1985-06-01 | 1990-01-03 | Dr. Karl Thomae GmbH | Neue heteroaromatische Aminderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| GB9221761D0 (en) | 1992-10-16 | 1992-12-02 | Glaxo Group Ltd | Chemical compounds |
| AU679635B2 (en) | 1994-03-11 | 1997-07-03 | Eli Lilly And Company | Method for treating 5HT-2B receptor related conditions |
| JPH09124643A (ja) * | 1995-08-14 | 1997-05-13 | Bristol Myers Squibb Co | 抗うつ作用を有する１−アリールアルキル−４−（アルコキシピリジニル）−又は４−（アルコキシピリミジニル）ピペラジン誘導体 |
| CA2268164A1 (en) | 1996-10-08 | 1998-04-16 | Yao-Chang Xu | New serotonin 5-ht1f agonists |
| HUP0101475A3 (en) * | 1998-06-19 | 2003-01-28 | Lundbeck & Co As H | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
| DE19948417A1 (de) * | 1999-10-07 | 2001-04-19 | Morphochem Ag | Imidazol-Derivate und ihre Verwendung als Arzneimittel |
| US7276603B2 (en) * | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| SA05260357B1 (ar) | 2004-11-19 | 2008-09-08 | ارينا فارماسيتو تيكالز ، أنك | مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به |
| JP5315060B2 (ja) | 2006-02-03 | 2013-10-16 | バイオノミックス リミテッド | 置換ベンゾフラン、ベンゾチオフェン、ベンゾセレノフェンおよびインドールおよびそれらのチューブリン重合阻害剤としての使用 |
| US20070293475A1 (en) | 2006-06-20 | 2007-12-20 | Alcon Manufacturing Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| CN103906742A (zh) | 2011-09-28 | 2014-07-02 | 世宗大学校产学协力团 | 硒吩稠合芳族化合物和其制备方法 |
| WO2014018888A1 (en) * | 2012-07-26 | 2014-01-30 | Confluence Life Sciences Inc. | 4-alkoxy/aralkoxy-5-substituted-pyrrolopyrimidine compounds as tak1 inhibitors in disease treatment |
| US10077267B2 (en) | 2014-04-04 | 2018-09-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP3519816A4 (en) * | 2016-09-29 | 2020-05-06 | The Regents of the University of California | CONNECTIONS FOR INCREASING NEURONAL PLASTICITY |
| WO2018133835A1 (en) * | 2017-01-20 | 2018-07-26 | National Institute Of Biological Sciences, Beijing | Nucleoside analogue regulating mammalian circadian rhythm |
| CA3052974A1 (en) * | 2017-02-09 | 2018-08-16 | CaaMTech, LLC | Compositions and methods comprising a psilocybin derivative |
| KR102946120B1 (ko) | 2019-02-27 | 2026-03-30 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클 |
| GB201907871D0 (en) * | 2019-06-03 | 2019-07-17 | Small Pharma Ltd | Therapeutic compositions |
| EP4017859A4 (en) | 2019-08-25 | 2023-08-23 | Caamtech, LLC | ALKYL QUARTERNARY AMMONIUM TRYPTAMINE AND THEIR THERAPEUTIC USES |
| EP4080407B1 (en) | 2019-12-20 | 2026-02-25 | BOE Technology Group Co., Ltd. | Inference computing apparatus, model training apparatus, and inference computing system |
| KR20220137081A (ko) | 2020-02-04 | 2022-10-11 | 마인드셋 파마 인크. | Cns 장애의 치료를 위한 세로토닌성 사이키델릭 작용제로서의 실로신 유도체 |
| EP4165049A4 (en) | 2020-06-10 | 2024-09-11 | Delix Therapeutics, Inc. | ISOTRYPTAMIN PSYCOPLASTIOGENS AND USES THEREOF |
| CN119285527A (zh) | 2020-06-30 | 2025-01-10 | 瑞安神经科学公司 | 色胺前药 |
| EP4255422A4 (en) | 2020-12-03 | 2024-12-18 | Mydecine Innovations Group Inc. | NEW PSILOCIN ANALOGUE COMPOSITIONS AND METHODS OF THEIR SYNTHESIS |
| CN117177959A (zh) | 2021-03-18 | 2023-12-05 | 赛本爱尔兰有限公司 | 裸头草碱类似物、盐、组合物和使用方法 |
| JP2024520485A (ja) | 2021-05-26 | 2024-05-24 | ブライト マインズ バイオサイエンスィズ インコーポレイテッド | 複素環式化合物及びその調製方法 |
| KR20240058859A (ko) | 2021-08-12 | 2024-05-03 | 쿨레온 엘엘씨 | 환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 |
| WO2023114238A1 (en) | 2021-12-15 | 2023-06-22 | Delix Therapeutics, Inc. | Aryloxy psychoplastogens and uses thereof |
| CN118974044A (zh) | 2021-12-24 | 2024-11-15 | 赛洛私人有限公司 | 化合物 |
| WO2023219789A1 (en) | 2022-05-10 | 2023-11-16 | Mydecine Innovations Group Inc. | Novel psilocin prodrug compounds and methods of synthesizing the same |
| IL318840A (en) * | 2022-08-11 | 2025-04-01 | Gilgamesh Pharmaceuticals Inc | Tryptamines and methods of treating mood disorders |
| WO2025042884A2 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Serotonin receptor modulators for the treatment of addictions and overdoses |
| WO2025042885A1 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Salts and solid forms of benzothiophene and benzoselenophene serotonin receptor modulators |
-
2022
- 2022-08-11 KR KR1020247007510A patent/KR20240058859A/ko active Pending
- 2022-08-11 CA CA3229044A patent/CA3229044A1/en active Pending
- 2022-08-11 IL IL310378A patent/IL310378A/en unknown
- 2022-08-11 JP JP2024508631A patent/JP2024531229A/ja active Pending
- 2022-08-11 EP EP22856602.2A patent/EP4384172A4/en active Pending
- 2022-08-11 AU AU2022328217A patent/AU2022328217A1/en active Pending
- 2022-08-11 WO PCT/US2022/040048 patent/WO2023018864A1/en not_active Ceased
-
2023
- 2023-04-25 US US18/306,652 patent/US11780807B2/en active Active
- 2023-07-28 US US18/360,976 patent/US12187678B2/en active Active
- 2023-12-12 US US18/536,542 patent/US12012380B1/en active Active
-
2024
- 2024-06-13 US US18/741,888 patent/US12275701B2/en active Active
- 2024-12-04 US US18/968,441 patent/US12344582B2/en active Active
-
2025
- 2025-04-09 US US19/174,214 patent/US20250340513A1/en active Pending
- 2025-05-22 US US19/215,938 patent/US12441683B2/en active Active
- 2025-12-08 US US19/412,382 patent/US20260092034A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20260092034A1 (en) | 2026-04-02 |
| US20250340513A1 (en) | 2025-11-06 |
| AU2022328217A1 (en) | 2024-03-14 |
| US12187678B2 (en) | 2025-01-07 |
| US12344582B2 (en) | 2025-07-01 |
| US20250282722A1 (en) | 2025-09-11 |
| US20230257346A1 (en) | 2023-08-17 |
| US20250091991A1 (en) | 2025-03-20 |
| EP4384172A1 (en) | 2024-06-19 |
| JP2024531229A (ja) | 2024-08-29 |
| KR20240058859A (ko) | 2024-05-03 |
| EP4384172A4 (en) | 2025-07-30 |
| US12012380B1 (en) | 2024-06-18 |
| CA3229044A1 (en) | 2023-02-16 |
| WO2023018864A1 (en) | 2023-02-16 |
| US12275701B2 (en) | 2025-04-15 |
| US11780807B2 (en) | 2023-10-10 |
| US20240190819A1 (en) | 2024-06-13 |
| US20240124397A1 (en) | 2024-04-18 |
| US12441683B2 (en) | 2025-10-14 |
| US20240343690A1 (en) | 2024-10-17 |
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