IL308240A - Conjugated polypeptides - Google Patents

Conjugated polypeptides

Info

Publication number
IL308240A
IL308240A IL308240A IL30824023A IL308240A IL 308240 A IL308240 A IL 308240A IL 308240 A IL308240 A IL 308240A IL 30824023 A IL30824023 A IL 30824023A IL 308240 A IL308240 A IL 308240A
Authority
IL
Israel
Prior art keywords
fusion polypeptides
polypeptides
fusion
Prior art date
Application number
IL308240A
Other languages
English (en)
Hebrew (he)
Inventor
Michael Schmidt
Grigorios Zarbis-Papastoitsis
Karl Dane Wittrup
Darrell Irvine
Original Assignee
Ankyra Therapeutics Inc
Michael Schmidt
Zarbis Papastoitsis Grigorios
Karl Dane Wittrup
Darrell Irvine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ankyra Therapeutics Inc, Michael Schmidt, Zarbis Papastoitsis Grigorios, Karl Dane Wittrup, Darrell Irvine filed Critical Ankyra Therapeutics Inc
Publication of IL308240A publication Critical patent/IL308240A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5434—IL-12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/11001—Non-specific serine/threonine protein kinase (2.7.11.1), i.e. casein kinase or checkpoint kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL308240A 2021-05-05 2022-05-04 Conjugated polypeptides IL308240A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163184620P 2021-05-05 2021-05-05
PCT/US2022/027617 WO2022235755A2 (en) 2021-05-05 2022-05-04 Fusion polypeptides

Publications (1)

Publication Number Publication Date
IL308240A true IL308240A (en) 2024-01-01

Family

ID=82020825

Family Applications (1)

Application Number Title Priority Date Filing Date
IL308240A IL308240A (en) 2021-05-05 2022-05-04 Conjugated polypeptides

Country Status (8)

Country Link
US (3) US12454695B2 (enExample)
EP (1) EP4334337A2 (enExample)
JP (1) JP2024517855A (enExample)
KR (1) KR20240028341A (enExample)
AU (1) AU2022269602A1 (enExample)
CA (1) CA3217079A1 (enExample)
IL (1) IL308240A (enExample)
WO (1) WO2022235755A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12454695B2 (en) 2021-05-05 2025-10-28 Ankyra Therapeutics, Inc. Fusion polypeptides comprising interleukin 12 and a metal-hydroxide binding polypeptide
IL312221A (en) 2021-10-20 2024-06-01 Synthekine Inc Heterodimeric fc cytokines and uses thereof
EP4615976A2 (en) * 2022-11-09 2025-09-17 Ankyra Therapeutics, Inc. Methods of making fusion polypeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202100935TA (en) 2018-09-28 2021-02-25 Massachusetts Inst Technology Collagen-localized immunomodulatory molecules and methods thereof
JP2022538974A (ja) 2019-06-26 2022-09-07 マサチューセッツ インスチテュート オブ テクノロジー 免疫調節融合タンパク質-金属水酸化物錯体およびその方法
US12454695B2 (en) 2021-05-05 2025-10-28 Ankyra Therapeutics, Inc. Fusion polypeptides comprising interleukin 12 and a metal-hydroxide binding polypeptide

Also Published As

Publication number Publication date
US20220372495A1 (en) 2022-11-24
EP4334337A2 (en) 2024-03-13
WO2022235755A2 (en) 2022-11-10
KR20240028341A (ko) 2024-03-05
US20250327085A1 (en) 2025-10-23
JP2024517855A (ja) 2024-04-23
US12454695B2 (en) 2025-10-28
CA3217079A1 (en) 2022-11-10
US20260035706A1 (en) 2026-02-05
AU2022269602A1 (en) 2023-11-09
WO2022235755A3 (en) 2022-12-29

Similar Documents

Publication Publication Date Title
IL289122A (en) polypeptides
IL308509A (en) Transgenic polypeptides
IL289119A (en) polypeptides
SG11202101904UA (en) Spd-1 variant - fc fusion proteins
GB202007441D0 (en) Polypeptide
GB202017649D0 (en) Polypeptide
IL290675A (en) Therapeutic fusion proteins
IL308465A (en) SARS-COV-2 polypeptides
ZA202102533B (en) Fusion protein
IL299811A (en) polypeptide
GB202113559D0 (en) Fusion polypeptide
SG11202011353XA (en) Stable fusion protein formulation
GB202019908D0 (en) Cripr polypeptides
GB202007532D0 (en) Polypeptides
SG11202102378WA (en) Arginase1 polypeptides
GB201913804D0 (en) Fusion polypeptides
GB202019879D0 (en) Polypeptide
GB202315671D0 (en) Polypeptides
GB202307936D0 (en) Fusion protein
GB202307932D0 (en) Fusion protein
GB202105044D0 (en) Fusion protein
GB202219576D0 (en) Polypeptides
HK40109940A (en) Fusion polypeptides
GB202111640D0 (en) Polypeptides
GB201900621D0 (en) Labelled polypeptides