IL308083A - Methods and compositions for treatment of diabetic retinopathy and related conditions - Google Patents

Methods and compositions for treatment of diabetic retinopathy and related conditions

Info

Publication number
IL308083A
IL308083A IL308083A IL30808323A IL308083A IL 308083 A IL308083 A IL 308083A IL 308083 A IL308083 A IL 308083A IL 30808323 A IL30808323 A IL 30808323A IL 308083 A IL308083 A IL 308083A
Authority
IL
Israel
Prior art keywords
compositions
treatment
methods
diabetic retinopathy
related conditions
Prior art date
Application number
IL308083A
Other languages
English (en)
Hebrew (he)
Inventor
Mina Sooch
Konstantinos Charizanis
Mark R Kelley
Richard Adam Messmann
Mitchell George Brigell
Ronil Ajaykumar Patel
Original Assignee
Ocuphire Pharma Inc
Mina Sooch
Konstantinos Charizanis
Mark R Kelley
Richard Adam Messmann
Mitchell George Brigell
Ronil Ajaykumar Patel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ocuphire Pharma Inc, Mina Sooch, Konstantinos Charizanis, Mark R Kelley, Richard Adam Messmann, Mitchell George Brigell, Ronil Ajaykumar Patel filed Critical Ocuphire Pharma Inc
Publication of IL308083A publication Critical patent/IL308083A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL308083A 2021-04-30 2022-04-29 Methods and compositions for treatment of diabetic retinopathy and related conditions IL308083A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163182037P 2021-04-30 2021-04-30
PCT/US2022/027062 WO2022232597A1 (en) 2021-04-30 2022-04-29 Methods and compositions for treatment of diabetic retinopathy and related conditions

Publications (1)

Publication Number Publication Date
IL308083A true IL308083A (en) 2023-12-01

Family

ID=83848745

Family Applications (1)

Application Number Title Priority Date Filing Date
IL308083A IL308083A (en) 2021-04-30 2022-04-29 Methods and compositions for treatment of diabetic retinopathy and related conditions

Country Status (11)

Country Link
US (1) US20240216315A1 (enExample)
EP (1) EP4329741A4 (enExample)
JP (1) JP2024516003A (enExample)
KR (1) KR20240049212A (enExample)
CN (1) CN117500492A (enExample)
AU (1) AU2022264037A1 (enExample)
BR (1) BR112023022561A2 (enExample)
CA (1) CA3217136A1 (enExample)
IL (1) IL308083A (enExample)
MX (1) MX2023012793A (enExample)
WO (1) WO2022232597A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4587003A2 (en) 2022-09-14 2025-07-23 Opus Genetics, Inc. Salts and esters of apx3330 and therapeutic uses thereof
WO2024158972A1 (en) * 2023-01-25 2024-08-02 Ocuphire Pharma, Inc. Methods and compositions for preventing the progression of diabetic retinopathy and related conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008304619C1 (en) * 2007-09-26 2020-06-04 Indiana University Research And Technology Corporation Benzoquinone derivative E3330 in combination with chemotherapeutic agents for the treatment of cancer and angiogenesis
AU2019218797B2 (en) * 2018-02-08 2023-09-21 Indiana University Research And Technology Corporation Targeting ocular diseases with novel APE1/Ref-1 inhibitors

Also Published As

Publication number Publication date
BR112023022561A2 (pt) 2024-01-02
MX2023012793A (es) 2024-01-11
US20240216315A1 (en) 2024-07-04
CA3217136A1 (en) 2022-11-03
JP2024516003A (ja) 2024-04-11
CN117500492A (zh) 2024-02-02
AU2022264037A1 (en) 2023-11-16
EP4329741A4 (en) 2025-01-08
EP4329741A1 (en) 2024-03-06
WO2022232597A1 (en) 2022-11-03
KR20240049212A (ko) 2024-04-16

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