IL305836A - A method for treating psoriatic arthritis patients with insufficient response to TNF therapy with a specific anti-IL23 antibody - Google Patents

A method for treating psoriatic arthritis patients with insufficient response to TNF therapy with a specific anti-IL23 antibody

Info

Publication number
IL305836A
IL305836A IL305836A IL30583623A IL305836A IL 305836 A IL305836 A IL 305836A IL 305836 A IL305836 A IL 305836A IL 30583623 A IL30583623 A IL 30583623A IL 305836 A IL305836 A IL 305836A
Authority
IL
Israel
Prior art keywords
specific antibody
psoriatic arthritis
arthritis patients
inadequate response
tnf therapy
Prior art date
Application number
IL305836A
Other languages
English (en)
Hebrew (he)
Inventor
Elizabeth C Hsia
Chetan Karyekar
Alexa Kollmeier
Wim Noel
Jaime Oliver Vigueras
Agata Schubert-Wlodarczyk
May Shawi
Virginia Taliadouros
Elke Theander
Xie Xu
Original Assignee
Janssen Biotech Inc
Elizabeth C Hsia
Chetan Karyekar
Alexa Kollmeier
Wim Noel
Jaime Oliver Vigueras
Schubert Wlodarczyk Agata
May Shawi
Virginia Taliadouros
Elke Theander
Xie Xu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc, Elizabeth C Hsia, Chetan Karyekar, Alexa Kollmeier, Wim Noel, Jaime Oliver Vigueras, Schubert Wlodarczyk Agata, May Shawi, Virginia Taliadouros, Elke Theander, Xie Xu filed Critical Janssen Biotech Inc
Publication of IL305836A publication Critical patent/IL305836A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
IL305836A 2021-03-12 2022-03-10 A method for treating psoriatic arthritis patients with insufficient response to TNF therapy with a specific anti-IL23 antibody IL305836A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163160078P 2021-03-12 2021-03-12
US202163188707P 2021-05-14 2021-05-14
PCT/IB2022/052163 WO2022190034A1 (en) 2021-03-12 2022-03-10 Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody

Publications (1)

Publication Number Publication Date
IL305836A true IL305836A (en) 2023-11-01

Family

ID=80786838

Family Applications (1)

Application Number Title Priority Date Filing Date
IL305836A IL305836A (en) 2021-03-12 2022-03-10 A method for treating psoriatic arthritis patients with insufficient response to TNF therapy with a specific anti-IL23 antibody

Country Status (10)

Country Link
US (1) US20220289834A1 (https=)
EP (1) EP4305062A1 (https=)
JP (1) JP2024510588A (https=)
KR (1) KR20230156764A (https=)
AU (1) AU2022232007A1 (https=)
BR (1) BR112023018400A2 (https=)
CA (1) CA3213278A1 (https=)
IL (1) IL305836A (https=)
MX (1) MX2023010697A (https=)
WO (1) WO2022190034A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021014953A (es) * 2019-06-04 2022-01-24 Janssen Biotech Inc Metodo seguro y eficaz para tratar la artritis psoriasica con el anticuerpo especifico anti-il23.
MX2023010705A (es) * 2021-03-12 2023-11-22 Janssen Biotech Inc Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23.
WO2024228134A1 (en) * 2023-05-03 2024-11-07 Janssen Biotech, Inc. Method of treating ulcerative colitis with a combination of antibodies to il-23 and tnf alpha
EP4704895A1 (en) * 2023-05-03 2026-03-11 Janssen Biotech, Inc. Method of treating crohn's disease with a combination of antibodies to il-23 and tnf alpha
AU2024323792A1 (en) * 2023-08-11 2026-03-12 Innovent Biologics (Suzhou) Co., Ltd. Method for treating plaque psoriasis wherein subject previously receiving biologic therapy for plaque psoriasis switches to using anti-il23p19 antibody

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Also Published As

Publication number Publication date
JP2024510588A (ja) 2024-03-08
AU2022232007A1 (en) 2023-10-26
AU2022232007A9 (en) 2023-11-02
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