IL303578A - Polypeptides and their uses - Google Patents

Polypeptides and their uses

Info

Publication number
IL303578A
IL303578A IL303578A IL30357823A IL303578A IL 303578 A IL303578 A IL 303578A IL 303578 A IL303578 A IL 303578A IL 30357823 A IL30357823 A IL 30357823A IL 303578 A IL303578 A IL 303578A
Authority
IL
Israel
Prior art keywords
aib
xaa
c18diacid
cntatc
amide
Prior art date
Application number
IL303578A
Other languages
English (en)
Hebrew (he)
Original Assignee
Medimmune Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Ltd filed Critical Medimmune Ltd
Publication of IL303578A publication Critical patent/IL303578A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL303578A 2020-12-16 2021-12-15 Polypeptides and their uses IL303578A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063125996P 2020-12-16 2020-12-16
PCT/EP2021/086034 WO2022129254A1 (en) 2020-12-16 2021-12-15 Polypeptides and uses thereof

Publications (1)

Publication Number Publication Date
IL303578A true IL303578A (en) 2023-08-01

Family

ID=79287870

Family Applications (1)

Application Number Title Priority Date Filing Date
IL303578A IL303578A (en) 2020-12-16 2021-12-15 Polypeptides and their uses

Country Status (16)

Country Link
US (3) US20240067693A1 (enExample)
EP (1) EP4263586A1 (enExample)
JP (1) JP7767428B2 (enExample)
KR (1) KR20230120134A (enExample)
CN (1) CN116685599A (enExample)
AR (1) AR124391A1 (enExample)
AU (2) AU2021399076B2 (enExample)
CA (1) CA3204296A1 (enExample)
CL (1) CL2023001719A1 (enExample)
CO (1) CO2023009066A2 (enExample)
CR (1) CR20230311A (enExample)
EC (1) ECSP23052600A (enExample)
IL (1) IL303578A (enExample)
MX (1) MX2023007288A (enExample)
TW (1) TW202241933A (enExample)
WO (1) WO2022129254A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240067693A1 (en) 2020-12-16 2024-02-29 Medimmune Limited Polypeptides and uses thereof
JP7604666B2 (ja) 2021-01-20 2024-12-23 バイキング・セラピューティクス・インコーポレイテッド 代謝及び肝臓障害の処置のための組成物及び方法
WO2023044290A1 (en) 2021-09-15 2023-03-23 Viking Therapeutics, Inc. Compositions and methods for the treatment of metabolic and liver disorders
US12116388B2 (en) 2022-12-22 2024-10-15 Novo Nordisk A/S Amylin receptor agonists
GB2641696A (en) * 2023-02-10 2025-12-10 Hangzhou Sciwind Biosciences Co Ltd Polypeptide and derivative thereof, composition, and use thereof
JP7755031B2 (ja) 2023-11-30 2025-10-15 ノヴォ ノルディスク アー/エス Glp-1、gip、およびアミリン受容体の三重作動薬
WO2025147628A2 (en) * 2024-01-05 2025-07-10 Indiana University Research And Technology Corporation Dual amylin calcitonin receptor agonists
WO2025242620A1 (en) 2024-05-20 2025-11-27 Medimmune Limited Polypeptide combinations and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051014A1 (de) 2004-10-20 2006-04-27 Rwth Aachen Chemisch modifizierte Peptidanaloga
WO2007104789A2 (en) * 2006-03-15 2007-09-20 Novo Nordisk A/S Amylin derivatives
EP2036923A1 (en) 2007-09-11 2009-03-18 Novo Nordisk A/S Improved derivates of amylin
EP2340261B1 (en) * 2008-10-21 2017-12-20 Novo Nordisk A/S Amylin derivatives
US9205135B2 (en) * 2009-09-22 2015-12-08 University Of Miami Podocyte pH modulation and uses thereof
WO2013059336A1 (en) 2011-10-18 2013-04-25 Amylin Pharmaceuticals, Llc Amylin-calcitonin chimeric peptides conjugated to duration enchancing moieties
CA2933405A1 (en) * 2013-12-13 2015-06-18 Medimmune Limited Protease-resistant peptides
ES2739289T3 (es) 2014-11-27 2020-01-30 Novo Nordisk As Derivados de GLP-1 y sus usos
BR112021006823A2 (pt) 2018-10-11 2021-07-27 Intarcia Therapeutics, Inc. polipeptídeos análogos de amilina humana e métodos de uso
WO2020225781A1 (en) 2019-05-08 2020-11-12 Auckland Uniservices Limited Peptide conjugate amylin agonists and uses thereof
US20240067693A1 (en) 2020-12-16 2024-02-29 Medimmune Limited Polypeptides and uses thereof

Also Published As

Publication number Publication date
ECSP23052600A (es) 2023-08-31
TW202241933A (zh) 2022-11-01
US20220204580A1 (en) 2022-06-30
JP2023554046A (ja) 2023-12-26
KR20230120134A (ko) 2023-08-16
CL2023001719A1 (es) 2024-01-26
AR124391A1 (es) 2023-03-22
MX2023007288A (es) 2023-07-03
US20250289860A1 (en) 2025-09-18
AU2021399076A1 (en) 2023-07-27
US20240067693A1 (en) 2024-02-29
AU2021399076B2 (en) 2024-07-11
CN116685599A (zh) 2023-09-01
CA3204296A1 (en) 2022-06-23
JP7767428B2 (ja) 2025-11-11
EP4263586A1 (en) 2023-10-25
CR20230311A (es) 2023-09-01
US12371464B2 (en) 2025-07-29
AU2021399076A9 (en) 2024-07-18
CO2023009066A2 (es) 2023-07-10
WO2022129254A1 (en) 2022-06-23
AU2024227071A1 (en) 2024-10-24

Similar Documents

Publication Publication Date Title
AU2021399076B2 (en) Polypeptides and uses thereof
US12371465B2 (en) Incretin analogs and uses thereof
CA3084004C (en) Incretin analogs and uses thereof
KR102824306B1 (ko) 인크레틴 유사체 및 그의 용도
CN102197049B (zh) 胰岛淀粉样多肽衍生物
JP2011525895A (ja) アミリン及びサケカルシトニンの誘導体化ハイブリッドペプチド
EA050089B1 (ru) Полипептиды и варианты их применения