IL301055A - Sulfamoylurea derivatives including an alkyl-oxycycloalkyl unit and their uses - Google Patents

Sulfamoylurea derivatives including an alkyl-oxycycloalkyl unit and their uses

Info

Publication number
IL301055A
IL301055A IL301055A IL30105523A IL301055A IL 301055 A IL301055 A IL 301055A IL 301055 A IL301055 A IL 301055A IL 30105523 A IL30105523 A IL 30105523A IL 301055 A IL301055 A IL 301055A
Authority
IL
Israel
Prior art keywords
compound
disease
disorder
pct
pharmaceutical composition
Prior art date
Application number
IL301055A
Other languages
English (en)
Hebrew (he)
Original Assignee
Nodthera Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nodthera Ltd filed Critical Nodthera Ltd
Publication of IL301055A publication Critical patent/IL301055A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL301055A 2020-09-04 2021-09-03 Sulfamoylurea derivatives including an alkyl-oxycycloalkyl unit and their uses IL301055A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063074521P 2020-09-04 2020-09-04
PCT/US2021/049001 WO2022051582A1 (en) 2020-09-04 2021-09-03 Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof

Publications (1)

Publication Number Publication Date
IL301055A true IL301055A (en) 2023-05-01

Family

ID=77951864

Family Applications (1)

Application Number Title Priority Date Filing Date
IL301055A IL301055A (en) 2020-09-04 2021-09-03 Sulfamoylurea derivatives including an alkyl-oxycycloalkyl unit and their uses

Country Status (13)

Country Link
US (1) US20240043410A1 (enExample)
EP (1) EP4208459A1 (enExample)
JP (1) JP7865948B2 (enExample)
KR (1) KR20230061505A (enExample)
CN (1) CN116783184A (enExample)
AR (1) AR123435A1 (enExample)
AU (1) AU2021336518B2 (enExample)
BR (1) BR112023003792A2 (enExample)
CA (1) CA3191410A1 (enExample)
IL (1) IL301055A (enExample)
MX (1) MX2023002686A (enExample)
TW (1) TWI916398B (enExample)
WO (1) WO2022051582A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
HUE067378T2 (hu) 2019-06-12 2024-10-28 Nodthera Ltd Szulfonilurea származékok és alkalmazásaik
JP7661248B2 (ja) 2019-06-12 2025-04-14 ノッドセラ リミテッド スルホニル尿素誘導体及びその使用
KR20260115622A (ko) * 2023-11-17 2026-07-24 노드테라 리미티드 우레아 유도체의 제조 방법
CN122555701A (zh) 2023-11-17 2026-08-11 诺瑟拉有限公司 脲衍生物的形式和相关用途
TW202545527A (zh) * 2024-01-16 2025-12-01 英商諾得瑟拉公司 Nlrp3及glp-1a組合療法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
DK1270565T3 (da) 1997-01-29 2004-10-04 Pfizer 4-substitueret furan-2-sulfonamid og dets anvendelse i fremstillingen af sulfonylurinstofderivater
JP6929792B2 (ja) * 2015-02-16 2021-09-01 ザ ユニバーシティ オブ クィーンズランド スルホニル尿素及び関連化合物並びにその使用
JP7412328B2 (ja) 2017-07-24 2024-01-12 ノバルティス アーゲー Nlrp活性に関連する状態を治療するための化合物及び組成物
GB201721185D0 (en) * 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
SG11202101480XA (en) 2018-08-15 2021-03-30 Inflazome Ltd Novel sulfonamideurea compounds

Also Published As

Publication number Publication date
CA3191410A1 (en) 2022-03-10
TWI916398B (zh) 2026-03-01
BR112023003792A2 (pt) 2023-03-28
AU2021336518A1 (en) 2023-03-23
EP4208459A1 (en) 2023-07-12
AU2021336518B2 (en) 2026-05-21
MX2023002686A (es) 2023-04-03
AR123435A1 (es) 2022-11-30
JP2023540733A (ja) 2023-09-26
US20240043410A1 (en) 2024-02-08
KR20230061505A (ko) 2023-05-08
JP7865948B2 (ja) 2026-05-26
WO2022051582A1 (en) 2022-03-10
TW202229265A (zh) 2022-08-01
CN116783184A (zh) 2023-09-19

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