CA3191410A1 - Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof - Google Patents

Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof

Info

Publication number
CA3191410A1
CA3191410A1 CA3191410A CA3191410A CA3191410A1 CA 3191410 A1 CA3191410 A1 CA 3191410A1 CA 3191410 A CA3191410 A CA 3191410A CA 3191410 A CA3191410 A CA 3191410A CA 3191410 A1 CA3191410 A1 CA 3191410A1
Authority
CA
Canada
Prior art keywords
compound
disease
disorder
present disclosure
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3191410A
Other languages
English (en)
French (fr)
Inventor
Mark G. Bock
David Harrison
Jane E. SCANLON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nodthera Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA3191410A1 publication Critical patent/CA3191410A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3191410A 2020-09-04 2021-09-03 Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof Pending CA3191410A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063074521P 2020-09-04 2020-09-04
US63/074,521 2020-09-04
PCT/US2021/049001 WO2022051582A1 (en) 2020-09-04 2021-09-03 Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof

Publications (1)

Publication Number Publication Date
CA3191410A1 true CA3191410A1 (en) 2022-03-10

Family

ID=77951864

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3191410A Pending CA3191410A1 (en) 2020-09-04 2021-09-03 Sulphamoyl urea derivatives containing alkyl-oxacycloalkyl moiety and uses thereof

Country Status (11)

Country Link
US (1) US20240043410A1 (enExample)
EP (1) EP4208459A1 (enExample)
JP (1) JP2023540733A (enExample)
KR (1) KR20230061505A (enExample)
CN (1) CN116783184A (enExample)
AR (1) AR123435A1 (enExample)
BR (1) BR112023003792A2 (enExample)
CA (1) CA3191410A1 (enExample)
IL (1) IL301055A (enExample)
MX (1) MX2023002686A (enExample)
WO (1) WO2022051582A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
SI3983387T1 (sl) 2019-06-12 2024-09-30 NodThera Limited Derivati sulfoniluree in njihove uporabe
ES3056339T3 (en) 2019-06-12 2026-02-19 Nodthera Ltd Sulfonylurea derivatives and uses thereof
WO2025104244A1 (en) * 2023-11-17 2025-05-22 NodThera Limited Methods of preparing urea derivatives
AU2024381716A1 (en) 2023-11-17 2026-05-14 NodThera Limited Forms of urea derivatives and related uses
WO2025153532A1 (en) * 2024-01-16 2025-07-24 NodThera Limited Nlrp3 inhibitors and glp-1 agonists combination therapies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
JP3573757B2 (ja) 1997-01-29 2004-10-06 ファイザー・インク スルホニルウレア誘導体、およびインターロイキン−１の活性を制御する上でのスルホニルウレア誘導体の使用
HUE055755T2 (hu) * 2015-02-16 2021-12-28 Univ Queensland Szulfonolkarmabidok és rokon vegyületeik valamint felhasználásuk
HUE066566T2 (hu) 2017-07-24 2024-08-28 Novartis Ag Vegyületek és készítmények NLRP aktivitással összefüggõ állapotok kezelésére
GB201721185D0 (en) * 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
CN112672995A (zh) * 2018-08-15 2021-04-16 英夫拉索姆有限公司 新型磺酰胺脲化合物

Also Published As

Publication number Publication date
WO2022051582A1 (en) 2022-03-10
IL301055A (en) 2023-05-01
KR20230061505A (ko) 2023-05-08
AU2021336518A1 (en) 2023-03-23
TW202229265A (zh) 2022-08-01
MX2023002686A (es) 2023-04-03
US20240043410A1 (en) 2024-02-08
AR123435A1 (es) 2022-11-30
BR112023003792A2 (pt) 2023-03-28
JP2023540733A (ja) 2023-09-26
EP4208459A1 (en) 2023-07-12
CN116783184A (zh) 2023-09-19

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