IL294571A - rspo1 proteins and their uses - Google Patents
rspo1 proteins and their usesInfo
- Publication number
- IL294571A IL294571A IL294571A IL29457122A IL294571A IL 294571 A IL294571 A IL 294571A IL 294571 A IL294571 A IL 294571A IL 29457122 A IL29457122 A IL 29457122A IL 294571 A IL294571 A IL 294571A
- Authority
- IL
- Israel
- Prior art keywords
- protein
- rspo1
- seq
- spondin
- functional
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20305016 | 2020-01-10 | ||
| PCT/EP2021/050289 WO2021140209A1 (en) | 2020-01-10 | 2021-01-08 | Rspo1 proteins and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL294571A true IL294571A (en) | 2022-09-01 |
Family
ID=69185555
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL294571A IL294571A (en) | 2020-01-10 | 2021-01-08 | rspo1 proteins and their uses |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230241161A1 (https=) |
| EP (1) | EP4087863A1 (https=) |
| JP (2) | JP7767289B2 (https=) |
| KR (1) | KR20220152202A (https=) |
| CN (1) | CN114929731A (https=) |
| AU (1) | AU2021205639A1 (https=) |
| BR (1) | BR112022013468A2 (https=) |
| CA (1) | CA3163861A1 (https=) |
| IL (1) | IL294571A (https=) |
| WO (1) | WO2021140209A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120813594A (zh) * | 2023-01-19 | 2025-10-17 | 迪奥根克斯公司 | R-spondin蛋白的重组变体及其用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| GB8725529D0 (en) | 1987-10-30 | 1987-12-02 | Delta Biotechnology Ltd | Polypeptides |
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| WO2008046649A1 (en) | 2006-10-20 | 2008-04-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Rspondins as modulators of angiogenesis and vasculogenesis |
| WO2008088524A2 (en) * | 2006-12-28 | 2008-07-24 | Nuvelo, Inc. | Thrombospondin-domain-deficient r-spondin 1 protein as gastrointestinal tract epithelial proliferation factor |
| WO2013054307A2 (en) * | 2011-10-14 | 2013-04-18 | Novartis Ag | Antibodies and methods for wnt pathway-related diseases |
| WO2014059068A1 (en) * | 2012-10-11 | 2014-04-17 | The Trustees Of The University Of Pennsylvania | Methods for the treatment and prevention of osteoporosis and bone-related disorders |
| WO2016193497A1 (en) * | 2015-06-04 | 2016-12-08 | Ospedale San Raffaele Srl | Inhibitor of igfbp3/tmem219 axis and diabetes |
| JP2021020900A (ja) | 2019-07-29 | 2021-02-18 | 国立大学法人北海道大学 | 糖代謝異常改善剤 |
| IL310154A (en) * | 2021-07-15 | 2024-03-01 | Diogenx | Recombinant variants of r-spondin proteins and their use |
-
2021
- 2021-01-08 US US17/758,540 patent/US20230241161A1/en active Pending
- 2021-01-08 IL IL294571A patent/IL294571A/en unknown
- 2021-01-08 JP JP2022541989A patent/JP7767289B2/ja active Active
- 2021-01-08 EP EP21700006.6A patent/EP4087863A1/en active Pending
- 2021-01-08 WO PCT/EP2021/050289 patent/WO2021140209A1/en not_active Ceased
- 2021-01-08 CN CN202180008384.XA patent/CN114929731A/zh active Pending
- 2021-01-08 BR BR112022013468A patent/BR112022013468A2/pt unknown
- 2021-01-08 AU AU2021205639A patent/AU2021205639A1/en active Pending
- 2021-01-08 KR KR1020227027675A patent/KR20220152202A/ko active Pending
- 2021-01-08 CA CA3163861A patent/CA3163861A1/en active Pending
-
2025
- 2025-10-29 JP JP2025182517A patent/JP2026021430A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20220152202A (ko) | 2022-11-15 |
| EP4087863A1 (en) | 2022-11-16 |
| AU2021205639A1 (en) | 2022-07-14 |
| US20230241161A1 (en) | 2023-08-03 |
| CA3163861A1 (en) | 2021-07-15 |
| WO2021140209A1 (en) | 2021-07-15 |
| JP2026021430A (ja) | 2026-02-10 |
| JP2023509189A (ja) | 2023-03-07 |
| CN114929731A (zh) | 2022-08-19 |
| BR112022013468A2 (pt) | 2022-09-13 |
| JP7767289B2 (ja) | 2025-11-11 |
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