IL29296A - Reduced pyrimidine nucleoside and nucleotides - Google Patents

Reduced pyrimidine nucleoside and nucleotides

Info

Publication number
IL29296A
IL29296A IL29296A IL2929668A IL29296A IL 29296 A IL29296 A IL 29296A IL 29296 A IL29296 A IL 29296A IL 2929668 A IL2929668 A IL 2929668A IL 29296 A IL29296 A IL 29296A
Authority
IL
Israel
Prior art keywords
tetrahydro
group
hydrogen
hydroxy
compound
Prior art date
Application number
IL29296A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of IL29296A publication Critical patent/IL29296A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • C07H19/10Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL29296A 1967-01-30 1968-01-11 Reduced pyrimidine nucleoside and nucleotides IL29296A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61233167A 1967-01-30 1967-01-30
US63660867A 1967-05-08 1967-05-08
US66522467A 1967-09-05 1967-09-05

Publications (1)

Publication Number Publication Date
IL29296A true IL29296A (en) 1971-08-25

Family

ID=27417076

Family Applications (1)

Application Number Title Priority Date Filing Date
IL29296A IL29296A (en) 1967-01-30 1968-01-11 Reduced pyrimidine nucleoside and nucleotides

Country Status (9)

Country Link
US (1) US3462416A (de)
JP (1) JPS4819639B1 (de)
BE (1) BE710090A (de)
CH (2) CH503038A (de)
DE (1) DE1695976C3 (de)
FR (2) FR8380M (de)
GB (1) GB1193531A (de)
IL (1) IL29296A (de)
NL (1) NL144486B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894000A (en) * 1971-01-27 1975-07-08 Upjohn Co Ara-cytidine derivatives and process of preparation
US3960840A (en) * 1972-12-29 1976-06-01 University Of Illinois Foundaton Fluorescent derivatives of adenine-containing compounds
US3893998A (en) * 1973-02-22 1975-07-08 Univ Illinois Fluorescent derivatives of cytosine-containing compounds
US4017606A (en) * 1973-10-04 1977-04-12 The Upjohn Company Organic compounds and process
US4096324A (en) * 1975-07-07 1978-06-20 The Upjohn Company Cytidine nucleoside compound
US4058602A (en) * 1976-08-09 1977-11-15 The United States Of America As Represented By The Department Of Health, Education And Welfare Synthesis, structure, and antitumor activity of 5,6-dihydro-5-azacytidine
DE2841898A1 (de) * 1978-09-26 1980-04-03 Robugen Gmbh Antivirales mittel auf der basis von 5-niedrigalkyl-2'-desoxyuridin-5' -monophosphaten
GB2037289B (en) * 1978-10-31 1983-05-05 Katsunuma N Nucleoside derivatives and an antileukemial agent containing the same as an active ingredient
US4275057A (en) * 1980-01-28 1981-06-23 The United States Of America As Represented By The Department Of Health, Education And Welfare Seven-membered ring compounds as inhibitors of cytidine deaminase
US5527782A (en) * 1990-03-13 1996-06-18 Acic (Canada) Inc. 5-halo-2,3'-O-cyclocytidines
SE9701219D0 (sv) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
WO2014116755A1 (en) * 2013-01-22 2014-07-31 Massachusetts Institute Of Technology Uses of dihydro bases
WO2022008025A1 (en) * 2020-07-05 2022-01-13 Since & Technology Development Fund Authority 2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same

Also Published As

Publication number Publication date
US3462416A (en) 1969-08-19
FR8380M (de) 1971-03-01
CH503037A (de) 1971-02-15
NL6801191A (de) 1968-07-31
JPS4819639B1 (de) 1973-06-14
DE1695976B2 (de) 1980-12-18
GB1193531A (en) 1970-06-03
FR1579502A (de) 1969-08-29
BE710090A (de) 1968-07-30
CH503038A (de) 1971-02-15
NL144486B (nl) 1975-01-15
DE1695976C3 (de) 1981-10-01
DE1695976A1 (de) 1971-05-19

Similar Documents

Publication Publication Date Title
Israel et al. N-trifluoroacetyladriamycin-14-valerate, an analog with greater experimental antitumor activity and less toxicity than adriamycin
JP3160288B2 (ja) プリン ヌクレオシド類
US5559101A (en) L-ribofuranosyl nucleosides
US4880784A (en) Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
US5041426A (en) Immune system enhancing 3-β-d-ribofuranosylthiazolo[4,5-d]pyridimine nucleosides and nucleotides
DE3856557T2 (de) Acyldeoxyribonukleosid-Derivate und Verwendungen davon
CN107148424A (zh) 用于诱导细胞因子的环状二核苷酸
KR970005326B1 (ko) 신규 항바이러스제
HU229480B1 (en) Nucleoside analogs with carboxamidine modified monocyclic base
Gosselin et al. Systematic synthesis and biological evaluation of. alpha.-and. beta.-D-xylofuranosyl nucleosides of the five naturally occurring bases in nucleic acids and related analogs
MXPA97002932A (en) L-ribofuranosilnucleosi
IL29296A (en) Reduced pyrimidine nucleoside and nucleotides
US5661136A (en) 2-halo-2'-fluoro ARA adenosines as antinoplastic agents
US4017606A (en) Organic compounds and process
WO1991000867A1 (en) 5'-diphosphohexose nucleoside pharmaceutical compositions
US4058602A (en) Synthesis, structure, and antitumor activity of 5,6-dihydro-5-azacytidine
Skoda Azapyrimidine nucleosides
US5041542A (en) Substituted pyrimido[5,4-d]pyrimidine nucleosides
EP0162715B1 (de) Derivate von enzym-hemmender Griseolsäure und deren Verwendung
Long et al. Synthesis and antitumor antiviral activities of 1-. beta.-D-arabinofuranosylpyrimidine 3', 5'-cyclic phosphates
Korn et al. ENZYMATIC SYNTHESIS OF 4-AMINO-5-IMIDAZ-OLECARBOXAMIDE RIBOSIDE FROM 4-AMINO-5-IMIDAZOLECARBOXAMIDE AND RIBOSIDE-1-PHOSPHATE1
Rosowsky et al. Synthesis and in vivo antitumor activity of potential 5-fluorouracil prodrugs
Baker et al. An evaluation of certain chain-extended analogs of 9-. beta.-D-arabinofuranosyladenine for antiviral and cardiovascular activity
Schinazi et al. Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides
Dudycz et al. Synthesis and determination of antiviral activity of the 2'(3')-O-methyl derivatives of ribavirin (1-. beta.-D-ribofuranosyl-1, 2, 4-triazole-3-carboxamide)