IL292459A - Treatment of liver disorders - Google Patents

Treatment of liver disorders

Info

Publication number
IL292459A
IL292459A IL292459A IL29245922A IL292459A IL 292459 A IL292459 A IL 292459A IL 292459 A IL292459 A IL 292459A IL 29245922 A IL29245922 A IL 29245922A IL 292459 A IL292459 A IL 292459A
Authority
IL
Israel
Prior art keywords
compound
liver
patient
formula
pharmaceutically acceptable
Prior art date
Application number
IL292459A
Other languages
English (en)
Hebrew (he)
Original Assignee
Terns Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terns Pharmaceuticals Inc filed Critical Terns Pharmaceuticals Inc
Publication of IL292459A publication Critical patent/IL292459A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL292459A 2019-11-08 2020-11-06 Treatment of liver disorders IL292459A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962933277P 2019-11-08 2019-11-08
US202063004403P 2020-04-02 2020-04-02
PCT/US2020/059522 WO2021092474A1 (fr) 2019-11-08 2020-11-06 Traitement de troubles hépatiques

Publications (1)

Publication Number Publication Date
IL292459A true IL292459A (en) 2022-06-01

Family

ID=75849579

Family Applications (1)

Application Number Title Priority Date Filing Date
IL292459A IL292459A (en) 2019-11-08 2020-11-06 Treatment of liver disorders

Country Status (11)

Country Link
EP (1) EP4054567A4 (fr)
JP (1) JP2023501386A (fr)
KR (1) KR20220098168A (fr)
CN (1) CN114667142A (fr)
AU (1) AU2020380968A1 (fr)
BR (1) BR112022008639A2 (fr)
CA (1) CA3160445A1 (fr)
CL (1) CL2022001167A1 (fr)
IL (1) IL292459A (fr)
MX (1) MX2022005407A (fr)
WO (1) WO2021092474A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220184114A1 (en) 2020-12-14 2022-06-16 Regeneron Pharmaceuticals, Inc. Methods Of Treating Metabolic Disorders And Cardiovascular Disease With Inhibin Subunit Beta E (INHBE) Inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200906823A (en) * 2007-07-16 2009-02-16 Lilly Co Eli Compounds and methods for modulating FXR
US20140187633A1 (en) * 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
CA3019496A1 (fr) * 2016-03-28 2017-10-05 Intercept Pharmaceuticals, Inc. Medicament obtenu par combinaison d'un agoniste de fxr et d'arb
WO2018170173A1 (fr) * 2017-03-15 2018-09-20 Metacrine, Inc. Agonistes du récepteur farnésoïde x et leurs utilisations
US20210121493A1 (en) * 2017-07-25 2021-04-29 Cedars-Sinai Medical Center Methods for treating liver diseases
KR20210052507A (ko) * 2018-08-30 2021-05-10 테른스 파마슈티칼스, 인크. 간 장애 치료

Also Published As

Publication number Publication date
MX2022005407A (es) 2022-05-24
WO2021092474A1 (fr) 2021-05-14
EP4054567A4 (fr) 2024-01-10
JP2023501386A (ja) 2023-01-18
CL2022001167A1 (es) 2023-02-10
KR20220098168A (ko) 2022-07-11
EP4054567A1 (fr) 2022-09-14
BR112022008639A2 (pt) 2022-07-19
CA3160445A1 (fr) 2021-05-14
AU2020380968A1 (en) 2022-05-12
CN114667142A (zh) 2022-06-24

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