IL289995A - שיטה לקבלת מיטוכונדריון מתאים ומיטוכונדריון המתקבלים מכך - Google Patents
שיטה לקבלת מיטוכונדריון מתאים ומיטוכונדריון המתקבלים מכךInfo
- Publication number
- IL289995A IL289995A IL289995A IL28999522A IL289995A IL 289995 A IL289995 A IL 289995A IL 289995 A IL289995 A IL 289995A IL 28999522 A IL28999522 A IL 28999522A IL 289995 A IL289995 A IL 289995A
- Authority
- IL
- Israel
- Prior art keywords
- mitochondria
- cells
- obtaining
- mitochondria obtained
- obtaining mitochondria
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/16—Physical preservation processes
- A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Developmental Biology & Embryology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Toxicology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019136283 | 2019-07-24 | ||
| PCT/JP2020/029597 WO2021015298A1 (en) | 2019-07-24 | 2020-07-22 | Method of obtaining mitochondria from cells and obtained mitochondria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL289995A true IL289995A (he) | 2022-03-01 |
Family
ID=72603502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL289995A IL289995A (he) | 2019-07-24 | 2022-01-20 | שיטה לקבלת מיטוכונדריון מתאים ומיטוכונדריון המתקבלים מכך |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220267714A1 (he) |
| EP (1) | EP4004186A1 (he) |
| JP (2) | JP2022542495A (he) |
| KR (1) | KR20220041145A (he) |
| CN (1) | CN114127263B (he) |
| AU (1) | AU2020318633A1 (he) |
| BR (1) | BR112022001207A2 (he) |
| CA (1) | CA3148248A1 (he) |
| IL (1) | IL289995A (he) |
| MX (1) | MX2022000893A (he) |
| WO (1) | WO2021015298A1 (he) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113905724A (zh) * | 2019-04-15 | 2022-01-07 | 儿童医学中心公司 | 包含线粒体的雾化组合物及其使用方法 |
| CN113122497B (zh) * | 2021-04-26 | 2023-08-11 | 重庆理工大学 | 工程化线粒体及其制备方法 |
| KR102665782B1 (ko) * | 2022-03-29 | 2024-05-14 | 주식회사 파이안바이오테크놀로지 | 동결 및 동결건조된 미토콘드리아 및 이의 용도 |
| WO2023234678A1 (ko) * | 2022-05-30 | 2023-12-07 | 주식회사 파이안바이오테크놀로지 | 분리된 미토콘드리아를 유효성분으로 포함하는 고혈압성 질환 예방 또는 치료용 약학 조성물 |
| CN114908046B (zh) * | 2022-06-16 | 2024-01-02 | 四川大学 | 一种线粒体膜囊泡的制备方法 |
| WO2024010862A1 (en) | 2022-07-07 | 2024-01-11 | Luca Science Inc. | Organelle complexes |
| KR20250067801A (ko) | 2022-07-07 | 2025-05-15 | 루카 사이언스 가부시키가이샤 | 산화환원 조절 소기관 복합체 |
| CN115212188B (zh) * | 2022-07-29 | 2023-04-07 | 西安交通大学医学院第一附属医院 | 一种缺血脑区靶向纳米线粒体及其制备方法、用途 |
| US20260041767A1 (en) | 2022-08-02 | 2026-02-12 | National University Corporation Hokkaido University | Methods of improving cellular therapy with organelle complexes |
| CN121175033A (zh) | 2023-03-31 | 2025-12-19 | 卢卡科学株式会社 | 聚乙二醇化细胞器复合物 |
| CN117660314A (zh) * | 2023-11-02 | 2024-03-08 | 上海市第六人民医院 | 一种用于体外提取细胞线粒体的试剂盒和方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1247093B1 (en) * | 2000-01-14 | 2005-03-23 | MIGENIX Corp. | Screening assays using intramitochondrial calcium |
| US20020090619A1 (en) * | 2000-06-29 | 2002-07-11 | Pfeiffer Douglas R. | Methods for identifying mitochondrial divalent cation transporters |
| JP2003519505A (ja) * | 2001-01-16 | 2003-06-24 | マイトコー | ミトコンドリア内カルシウムを使用するスクリーニングアッセイ |
| US7407800B1 (en) * | 2003-09-19 | 2008-08-05 | Pierce Biotechnology, Inc. | Method for the isolation of intact mitochondria from cells |
| WO2010040901A1 (en) * | 2008-10-07 | 2010-04-15 | Pierre Rustin | Alternative oxidase and uses thereof |
| JP5729904B2 (ja) * | 2009-06-02 | 2015-06-03 | キヤノン株式会社 | 細胞から蛋白質、ｄｎａ、ｒｎａを調製する方法 |
| US8865416B2 (en) * | 2010-10-19 | 2014-10-21 | Georgia State University Research Foundation, Inc. | Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity |
| CN105008515A (zh) * | 2012-12-28 | 2015-10-28 | 小利兰·斯坦福大学托管委员会 | 用于治疗线粒体疾病和用于使细胞分化成神经元的组合物和方法 |
| WO2015047188A1 (en) * | 2013-09-30 | 2015-04-02 | Enza Biotech Ab | Surfactant composition |
| WO2017046794A1 (en) * | 2015-09-14 | 2017-03-23 | The National Institute for Biotechnology in the Negev Ltd. | Novel piperazine and piperidine derivatives, their synthesis and use thereof in inhibiting vdac oligomerization, apoptosis and mitochondria dysfunction |
| SI4272834T1 (sl) * | 2016-01-15 | 2026-03-31 | Beth Israel Deaconess Medical Center, Inc. | Terapevtska uporaba mitohondrijev in kombiniranih mitohondrijskih sredstev |
-
2020
- 2020-07-22 JP JP2022532237A patent/JP2022542495A/ja active Pending
- 2020-07-22 BR BR112022001207A patent/BR112022001207A2/pt not_active Application Discontinuation
- 2020-07-22 EP EP20775731.1A patent/EP4004186A1/en active Pending
- 2020-07-22 CA CA3148248A patent/CA3148248A1/en active Pending
- 2020-07-22 CN CN202080052575.1A patent/CN114127263B/zh active Active
- 2020-07-22 KR KR1020227006063A patent/KR20220041145A/ko active Pending
- 2020-07-22 AU AU2020318633A patent/AU2020318633A1/en active Pending
- 2020-07-22 WO PCT/JP2020/029597 patent/WO2021015298A1/en not_active Ceased
- 2020-07-22 MX MX2022000893A patent/MX2022000893A/es unknown
- 2020-07-22 US US17/628,834 patent/US20220267714A1/en active Pending
-
2022
- 2022-01-20 IL IL289995A patent/IL289995A/he unknown
-
2025
- 2025-04-07 JP JP2025062890A patent/JP2025118621A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025118621A (ja) | 2025-08-13 |
| CA3148248A1 (en) | 2021-01-28 |
| WO2021015298A1 (en) | 2021-01-28 |
| MX2022000893A (es) | 2022-03-22 |
| BR112022001207A2 (pt) | 2022-03-15 |
| US20220267714A1 (en) | 2022-08-25 |
| EP4004186A1 (en) | 2022-06-01 |
| KR20220041145A (ko) | 2022-03-31 |
| CN114127263A (zh) | 2022-03-01 |
| CN114127263B (zh) | 2024-12-06 |
| AU2020318633A1 (en) | 2022-02-24 |
| JP2022542495A (ja) | 2022-10-03 |
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