IL289438B1 - System and method for removal of immune inhibitors from biological fluids - Google Patents

System and method for removal of immune inhibitors from biological fluids

Info

Publication number
IL289438B1
IL289438B1 IL289438A IL28943821A IL289438B1 IL 289438 B1 IL289438 B1 IL 289438B1 IL 289438 A IL289438 A IL 289438A IL 28943821 A IL28943821 A IL 28943821A IL 289438 B1 IL289438 B1 IL 289438B1
Authority
IL
Israel
Prior art keywords
removal
biological fluids
immune inhibitors
immune
inhibitors
Prior art date
Application number
IL289438A
Other languages
Hebrew (he)
Other versions
IL289438A (en
IL289438B2 (en
Original Assignee
Immunicom Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunicom Inc filed Critical Immunicom Inc
Publication of IL289438A publication Critical patent/IL289438A/en
Publication of IL289438B1 publication Critical patent/IL289438B1/en
Publication of IL289438B2 publication Critical patent/IL289438B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0415—Plasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • External Artificial Organs (AREA)
IL289438A 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids IL289438B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/062177 WO2021101519A1 (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids

Publications (3)

Publication Number Publication Date
IL289438A IL289438A (en) 2022-02-01
IL289438B1 true IL289438B1 (en) 2023-05-01
IL289438B2 IL289438B2 (en) 2023-09-01

Family

ID=75980821

Family Applications (2)

Application Number Title Priority Date Filing Date
IL301912A IL301912A (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids
IL289438A IL289438B2 (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL301912A IL301912A (en) 2019-11-19 2019-11-19 System and method for removal of immune inhibitors from biological fluids

Country Status (8)

Country Link
EP (1) EP3846875A1 (en)
JP (2) JP7159493B2 (en)
KR (2) KR102491518B1 (en)
CN (1) CN114650852A (en)
AU (3) AU2019474912B2 (en)
CA (2) CA3153685C (en)
IL (2) IL301912A (en)
WO (1) WO2021101519A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116648272A (en) * 2020-10-01 2023-08-25 英谬免疫股份有限公司 Reducing ligand leakage
US11224858B1 (en) 2020-10-01 2022-01-18 Immunicom, Inc. Reduced leaching of a ligand

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1243298A1 (en) * 1999-11-02 2002-09-25 Kaneka Corporation Filling out-flow preventing filter and absorber attached with it
US20140074007A1 (en) * 2012-09-11 2014-03-13 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
WO2018020285A2 (en) * 2016-07-28 2018-02-01 Captec Medical Kft. Flow capture device and method for removing cells from blood

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2213079C (en) * 1995-02-16 2004-12-14 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adsorbent for tumor necrosis factor .alpha., method of removal by adsorption, and adsorption device using said adsorbent
US8197430B1 (en) * 1998-05-22 2012-06-12 Biopheresis Technologies, Inc. Method and system to remove cytokine inhibitor in patients
CN101124315A (en) * 2003-01-17 2008-02-13 伊势龙医学股份有限公司 Method for removal of viruses from blood by lectin affinity hemodialysis
JP4925159B2 (en) * 2005-10-12 2012-04-25 日機装株式会社 Blood purification equipment
AU2008293431B2 (en) * 2007-08-31 2013-07-04 Cytopherx, Inc. Selective cytopheresis devices and related methods thereof
US9227005B2 (en) * 2013-03-14 2016-01-05 Brian J LeBerthon Method and device for treating cancer
DK3110977T3 (en) * 2014-02-28 2018-07-23 Exosome Sciences Inc BRAIN SPECIFIC EXOSOME-BASED DIAGNOSTIC AND EXTRACORPORAL THERAPIES
US10639405B2 (en) 2014-07-22 2020-05-05 Asahi Kasei Medical Co., Ltd. Adsorbent for removing histone and purification device for liquid derived from living organism
US20190247560A1 (en) * 2018-02-13 2019-08-15 Gambro Lundia Ab Extracorporeal devices and methods of treating complement factor related diseases
DE102018104177A1 (en) 2018-02-23 2019-08-29 B. Braun Avitum Ag Apparatus for removing noxious substances from blood, extracorporeal perfusion system comprising such a device and method for producing such a device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1243298A1 (en) * 1999-11-02 2002-09-25 Kaneka Corporation Filling out-flow preventing filter and absorber attached with it
US20140074007A1 (en) * 2012-09-11 2014-03-13 Gary L. McNeil Closed-circuit device and methods for isolation, modification, and re-administration of specific constituents from a biological fluid source
WO2018020285A2 (en) * 2016-07-28 2018-02-01 Captec Medical Kft. Flow capture device and method for removing cells from blood

Also Published As

Publication number Publication date
AU2022203249B2 (en) 2023-08-31
CA3165330A1 (en) 2021-05-27
KR102491518B1 (en) 2023-01-20
CA3153685C (en) 2022-10-11
KR20220039724A (en) 2022-03-29
IL289438A (en) 2022-02-01
WO2021101519A1 (en) 2021-05-27
EP3846875A4 (en) 2021-07-14
AU2019474912A1 (en) 2022-01-06
JP2023015053A (en) 2023-01-31
JP2022535604A (en) 2022-08-09
IL301912A (en) 2023-06-01
IL289438B2 (en) 2023-09-01
JP7159493B2 (en) 2022-10-24
AU2022203249A1 (en) 2022-06-23
CA3153685A1 (en) 2021-05-27
AU2023274130A1 (en) 2023-12-21
AU2019474912B2 (en) 2022-02-17
CN114650852A (en) 2022-06-21
KR20230016032A (en) 2023-01-31
EP3846875A1 (en) 2021-07-14

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