SG11202012687SA - Method for detection and quantification of genetic alterations - Google Patents

Method for detection and quantification of genetic alterations

Info

Publication number
SG11202012687SA
SG11202012687SA SG11202012687SA SG11202012687SA SG11202012687SA SG 11202012687S A SG11202012687S A SG 11202012687SA SG 11202012687S A SG11202012687S A SG 11202012687SA SG 11202012687S A SG11202012687S A SG 11202012687SA SG 11202012687S A SG11202012687S A SG 11202012687SA
Authority
SG
Singapore
Prior art keywords
quantification
detection
genetic alterations
genetic
alterations
Prior art date
Application number
SG11202012687SA
Inventor
Yukti Choudhury
Hao Chen
Min-Han Tan
Original Assignee
Lucence Life Sciences Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lucence Life Sciences Pte Ltd filed Critical Lucence Life Sciences Pte Ltd
Publication of SG11202012687SA publication Critical patent/SG11202012687SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855Ligating adaptors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1252DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202012687SA 2018-06-25 2019-06-25 Method for detection and quantification of genetic alterations SG11202012687SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201805450Y 2018-06-25
PCT/SG2019/050317 WO2020005159A1 (en) 2018-06-25 2019-06-25 Method for detection and quantification of genetic alterations

Publications (1)

Publication Number Publication Date
SG11202012687SA true SG11202012687SA (en) 2021-01-28

Family

ID=68985923

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202012687SA SG11202012687SA (en) 2018-06-25 2019-06-25 Method for detection and quantification of genetic alterations

Country Status (4)

Country Link
EP (1) EP3810805A4 (en)
CN (1) CN112639127A (en)
SG (1) SG11202012687SA (en)
WO (1) WO2020005159A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113436679B (en) * 2020-03-23 2024-05-10 北京合生基因科技有限公司 Method and system for determining mutation rate of nucleic acid sample to be tested
WO2022025823A1 (en) * 2020-07-29 2022-02-03 Lucence Life Sciences Pte. Ltd Methods and kits for detecting and sequencing rna viruses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011019964A1 (en) * 2009-08-12 2011-02-17 Nugen Technologies, Inc. Methods, compositions, and kits for generating nucleic acid products substantially free of template nucleic acid
SG10202009015SA (en) * 2012-12-10 2020-10-29 Resolution Bioscience Inc Methods for targeted genomic analysis
WO2015039006A1 (en) * 2013-09-16 2015-03-19 The General Hospital Corporation Methods of treating cancer
CN114214314A (en) * 2014-06-24 2022-03-22 生物辐射实验室股份有限公司 Digital PCR barcoding
WO2016081798A1 (en) * 2014-11-20 2016-05-26 Children's Medical Center Corporation Methods relating to the detection of recurrent and non-specific double strand breaks in the genome
EP3551756A4 (en) * 2016-12-12 2020-07-15 Dana Farber Cancer Institute, Inc. Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection

Also Published As

Publication number Publication date
CN112639127A (en) 2021-04-09
WO2020005159A1 (en) 2020-01-02
EP3810805A1 (en) 2021-04-28
EP3810805A4 (en) 2022-03-23

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