IL288158A - Crystalline salt forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide - Google Patents
Crystalline salt forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamideInfo
- Publication number
- IL288158A IL288158A IL288158A IL28815821A IL288158A IL 288158 A IL288158 A IL 288158A IL 288158 A IL288158 A IL 288158A IL 28815821 A IL28815821 A IL 28815821A IL 288158 A IL288158 A IL 288158A
- Authority
- IL
- Israel
- Prior art keywords
- cyclopropylmethyl
- sulfonamide
- quinoline
- piperazine
- carbonyl
- Prior art date
Links
- XAYGBKHKBBXDAK-UHFFFAOYSA-N n-[4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide Chemical compound C=1C=C(NS(=O)(=O)C=2C3=NC=CC=C3C=CC=2)C=CC=1C(=O)N(CC1)CCN1CC1CC1 XAYGBKHKBBXDAK-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/29—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/13—Dicarboxylic acids
- C07C57/15—Fumaric acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962851344P | 2019-05-22 | 2019-05-22 | |
| PCT/US2020/033992 WO2020237047A1 (en) | 2019-05-22 | 2020-05-21 | Crystalline salt forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL288158A true IL288158A (en) | 2022-01-01 |
Family
ID=71016713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL288158A IL288158A (en) | 2019-05-22 | 2021-11-16 | Crystalline salt forms of n-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230192618A1 (enExample) |
| EP (1) | EP3972957A1 (enExample) |
| JP (1) | JP2022533227A (enExample) |
| CN (2) | CN118206485A (enExample) |
| AU (1) | AU2020280045A1 (enExample) |
| CA (1) | CA3145138A1 (enExample) |
| IL (1) | IL288158A (enExample) |
| MX (2) | MX2021014228A (enExample) |
| WO (1) | WO2020237047A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240107326A (ko) | 2021-11-16 | 2024-07-09 | 아지오스 파마슈티컬스 아이엔씨. | Mds 관련 빈혈 및 기타 상태를 치료하기 위한 화합물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602007011792D1 (de) * | 2006-10-27 | 2011-02-17 | Fmc Corp | Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen |
| PE20120693A1 (es) * | 2009-06-29 | 2012-07-04 | Agios Pharmaceuticals Inc | Compuestos heterociclos como moduladores de la piruvato cinasa m2 (pkm2) |
| UY36680A (es) * | 2015-05-19 | 2016-12-30 | Glaxosmithkline Ip Dev Ltd | Amidas heterocíclicas como inhibidores de quinasa |
| MX384883B (es) | 2015-06-11 | 2025-03-14 | Agios Pharmaceuticals Inc | Métodos para usar activadores de piruvato cinasa. |
| KR102682430B1 (ko) * | 2017-11-22 | 2024-07-08 | 아지오스 파마슈티컬스 아이엔씨. | N-(4-(4-(시클로프로필메틸)피페라진-1-카르보닐)페닐)퀴놀린-8-술폰아미드의 결정 형태 |
-
2020
- 2020-05-21 JP JP2021569059A patent/JP2022533227A/ja not_active Ceased
- 2020-05-21 US US17/612,554 patent/US20230192618A1/en not_active Abandoned
- 2020-05-21 CN CN202410205860.2A patent/CN118206485A/zh active Pending
- 2020-05-21 AU AU2020280045A patent/AU2020280045A1/en not_active Abandoned
- 2020-05-21 EP EP20731357.8A patent/EP3972957A1/en not_active Withdrawn
- 2020-05-21 WO PCT/US2020/033992 patent/WO2020237047A1/en not_active Ceased
- 2020-05-21 CA CA3145138A patent/CA3145138A1/en active Pending
- 2020-05-21 CN CN202080045139.1A patent/CN114026071B/zh not_active Expired - Fee Related
- 2020-05-21 MX MX2021014228A patent/MX2021014228A/es unknown
-
2021
- 2021-11-16 IL IL288158A patent/IL288158A/en unknown
- 2021-11-19 MX MX2024009648A patent/MX2024009648A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2024009648A (es) | 2024-08-19 |
| CN114026071A (zh) | 2022-02-08 |
| JP2022533227A (ja) | 2022-07-21 |
| AU2020280045A1 (en) | 2021-12-23 |
| MX2021014228A (es) | 2022-02-21 |
| CN118206485A (zh) | 2024-06-18 |
| CN114026071B (zh) | 2024-03-01 |
| EP3972957A1 (en) | 2022-03-30 |
| CA3145138A1 (en) | 2020-11-26 |
| US20230192618A1 (en) | 2023-06-22 |
| WO2020237047A1 (en) | 2020-11-26 |
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