IL285831B - Low sample volume sensing device - Google Patents
Low sample volume sensing deviceInfo
- Publication number
- IL285831B IL285831B IL285831A IL28583121A IL285831B IL 285831 B IL285831 B IL 285831B IL 285831 A IL285831 A IL 285831A IL 28583121 A IL28583121 A IL 28583121A IL 285831 B IL285831 B IL 285831B
- Authority
- IL
- Israel
- Prior art keywords
- flow path
- electrical contact
- reaction well
- sensor array
- sensing area
- Prior art date
Links
- 239000000758 substrate Substances 0.000 claims description 61
- 239000007788 liquid Substances 0.000 claims description 30
- 238000006243 chemical reaction Methods 0.000 claims description 29
- 239000012530 fluid Substances 0.000 claims description 13
- 239000004020 conductor Substances 0.000 claims description 9
- 239000003153 chemical reaction reagent Substances 0.000 claims description 6
- 239000012491 analyte Substances 0.000 claims 5
- 238000000034 method Methods 0.000 description 5
- 230000001953 sensory effect Effects 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 3
- 239000000203 mixture Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 238000005054 agglomeration Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000010288 cold spraying Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 239000002071 nanotube Substances 0.000 description 1
- 238000007649 pad printing Methods 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007650 screen-printing Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- 238000007751 thermal spraying Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- H—ELECTRICITY
- H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
- H10D—INORGANIC ELECTRIC SEMICONDUCTOR DEVICES
- H10D10/00—Bipolar junction transistors [BJT]
- H10D10/40—Vertical BJTs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/088—Channel loops
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Micromachines (AREA)
- Laminated Bodies (AREA)
- Optical Measuring Cells (AREA)
- Spectrometry And Color Measurement (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462022376P | 2014-07-09 | 2014-07-09 | |
| PCT/US2015/039695 WO2016007716A1 (en) | 2014-07-09 | 2015-07-09 | Low sample volume sensing device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL285831A IL285831A (en) | 2021-09-30 |
| IL285831B true IL285831B (en) | 2022-07-01 |
Family
ID=55064880
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL285831A IL285831B (en) | 2014-07-09 | 2015-07-09 | Low sample volume sensing device |
| IL249509A IL249509B (en) | 2014-07-09 | 2016-12-12 | Low sample volume sensing device |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL249509A IL249509B (en) | 2014-07-09 | 2016-12-12 | Low sample volume sensing device |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10814322B2 (enExample) |
| EP (2) | EP4151313A1 (enExample) |
| JP (1) | JP6700246B2 (enExample) |
| CA (1) | CA2954563C (enExample) |
| DK (1) | DK3167254T3 (enExample) |
| IL (2) | IL285831B (enExample) |
| MX (1) | MX380896B (enExample) |
| WO (1) | WO2016007716A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6700246B2 (ja) * | 2014-07-09 | 2020-05-27 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． | 少量試料検知装置 |
| WO2017120464A1 (en) | 2016-01-08 | 2017-07-13 | Siemens Healthcare Diagnostics Inc. | Heating element for sensor array |
| WO2019099855A1 (en) * | 2017-11-17 | 2019-05-23 | Siemens Healthcare Diagnostics Inc. | Sensor assembly and method of using same |
| WO2020005697A1 (en) * | 2018-06-29 | 2020-01-02 | Siemens Healthcare Diagnostics Inc. | Sensor assembly for a sample fluid analysis system |
| JP7212135B2 (ja) | 2018-07-04 | 2023-01-24 | ラジオメーター・メディカル・アー・ペー・エス | マグネシウムイオン選択性膜 |
| US12044652B2 (en) | 2018-07-04 | 2024-07-23 | Radiometer Medical Aps | Ion selective membranes and the preparation thereof |
| WO2020007626A1 (en) | 2018-07-04 | 2020-01-09 | Radiometer Medical Aps | Magnesium ion selective pvc membranes |
| CN113841049A (zh) | 2019-05-14 | 2021-12-24 | 雷迪奥米特医学公司 | 测定血气或代谢参数的方法 |
| CA3143250C (en) | 2019-06-12 | 2024-03-05 | Siemens Healthcare Diagnostics Inc. | System and method of measurement and calibration of analyte testing |
| EP3994462A1 (en) | 2019-07-05 | 2022-05-11 | Radiometer Medical ApS | Sensor device |
| CN111672650B (zh) * | 2020-06-22 | 2022-03-08 | 成都中电熊猫显示科技有限公司 | 一种喷涂装置、喷涂方法及显示面板 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO855897A0 (en) | 1997-08-13 | 1997-09-04 | Usf Filtration And Separations Group Inc. | Automatic analysing apparatus II |
| US6258229B1 (en) * | 1999-06-02 | 2001-07-10 | Handani Winarta | Disposable sub-microliter volume sensor and method of making |
| US6896778B2 (en) | 2001-06-04 | 2005-05-24 | Epocal Inc. | Electrode module |
| US7932098B2 (en) | 2002-10-31 | 2011-04-26 | Hewlett-Packard Development Company, L.P. | Microfluidic system utilizing thin-film layers to route fluid |
| US7842234B2 (en) | 2002-12-02 | 2010-11-30 | Epocal Inc. | Diagnostic devices incorporating fluidics and methods of manufacture |
| US7682833B2 (en) * | 2003-09-10 | 2010-03-23 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
| US7332902B1 (en) * | 2004-11-02 | 2008-02-19 | Environmental Metrology Corporation | Micro sensor for electrochemically monitoring residue in micro channels |
| WO2007133457A2 (en) | 2006-05-08 | 2007-11-22 | Bayer Healthcare Llc | Electrochemical test sensor with reduced sample volume |
| JP2008082961A (ja) | 2006-09-28 | 2008-04-10 | Sumitomo Bakelite Co Ltd | マイクロ流路デバイス |
| US20080233011A1 (en) * | 2007-03-23 | 2008-09-25 | 3M Innovative Properties Company | Microfluidic devices |
| GB0705699D0 (en) | 2007-03-24 | 2007-05-02 | Oxford Biosensors Ltd | Reagent devices |
| EP1986007A1 (en) | 2007-04-27 | 2008-10-29 | Radiometer Medical ApS | A sensor assembly for body fluids |
| BRPI0813718A2 (pt) * | 2007-07-13 | 2014-12-30 | Univ Leland Stanford Junior | Método e aparelho que utilizam um campo elétrico para ensaios biológicos aperfeiçoados |
| US9044178B2 (en) * | 2007-08-30 | 2015-06-02 | Pepex Biomedical, Llc | Electrochemical sensor and method for manufacturing |
| US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
| EP2459730B1 (en) | 2009-07-27 | 2016-12-07 | Suresensors LTD | Improvements relating to sensor devices |
| KR101363020B1 (ko) | 2011-10-31 | 2014-02-26 | 주식회사 세라젬메디시스 | 다중 반응 바이오센서 |
| US8747748B2 (en) * | 2012-01-19 | 2014-06-10 | Life Technologies Corporation | Chemical sensor with conductive cup-shaped sensor surface |
| JP6700246B2 (ja) * | 2014-07-09 | 2020-05-27 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． | 少量試料検知装置 |
-
2015
- 2015-07-09 JP JP2017500371A patent/JP6700246B2/ja active Active
- 2015-07-09 EP EP22187547.9A patent/EP4151313A1/en active Pending
- 2015-07-09 MX MX2017000290A patent/MX380896B/es unknown
- 2015-07-09 DK DK15818776.5T patent/DK3167254T3/da active
- 2015-07-09 EP EP15818776.5A patent/EP3167254B1/en active Active
- 2015-07-09 US US15/324,122 patent/US10814322B2/en active Active
- 2015-07-09 IL IL285831A patent/IL285831B/en unknown
- 2015-07-09 CA CA2954563A patent/CA2954563C/en active Active
- 2015-07-09 WO PCT/US2015/039695 patent/WO2016007716A1/en not_active Ceased
-
2016
- 2016-12-12 IL IL249509A patent/IL249509B/en unknown
-
2020
- 2020-09-29 US US17/035,919 patent/US11850585B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL249509A0 (en) | 2017-02-28 |
| IL249509B (en) | 2021-09-30 |
| MX2017000290A (es) | 2017-08-25 |
| MX380896B (es) | 2025-03-12 |
| US20210008549A1 (en) | 2021-01-14 |
| DK3167254T3 (da) | 2022-12-12 |
| WO2016007716A1 (en) | 2016-01-14 |
| IL285831A (en) | 2021-09-30 |
| US11850585B2 (en) | 2023-12-26 |
| EP4151313A1 (en) | 2023-03-22 |
| JP2017523407A (ja) | 2017-08-17 |
| EP3167254A1 (en) | 2017-05-17 |
| CA2954563A1 (en) | 2016-01-14 |
| US10814322B2 (en) | 2020-10-27 |
| EP3167254B1 (en) | 2022-09-07 |
| EP3167254A4 (en) | 2017-08-02 |
| JP6700246B2 (ja) | 2020-05-27 |
| US20170203294A1 (en) | 2017-07-20 |
| CA2954563C (en) | 2021-06-22 |
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