IL281965B1 - Biphenyl sulfonamide compounds for the treatment of type IV collagen diseases - Google Patents
Biphenyl sulfonamide compounds for the treatment of type IV collagen diseasesInfo
- Publication number
- IL281965B1 IL281965B1 IL281965A IL28196521A IL281965B1 IL 281965 B1 IL281965 B1 IL 281965B1 IL 281965 A IL281965 A IL 281965A IL 28196521 A IL28196521 A IL 28196521A IL 281965 B1 IL281965 B1 IL 281965B1
- Authority
- IL
- Israel
- Prior art keywords
- treatment
- type
- sulfonamide compounds
- collagen diseases
- biphenyl sulfonamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Urology & Nephrology (AREA)
- Physiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862741270P | 2018-10-04 | 2018-10-04 | |
| US201962853904P | 2019-05-29 | 2019-05-29 | |
| US201962894559P | 2019-08-30 | 2019-08-30 | |
| PCT/US2019/054559 WO2020072814A1 (en) | 2018-10-04 | 2019-10-03 | Biphenyl sulfonamide compounds for the treatment of type iv collagen diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL281965A IL281965A (en) | 2021-05-31 |
| IL281965B1 true IL281965B1 (en) | 2026-04-01 |
Family
ID=68318947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL281965A IL281965B1 (en) | 2018-10-04 | 2019-10-03 | Biphenyl sulfonamide compounds for the treatment of type IV collagen diseases |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11207299B2 (https=) |
| EP (1) | EP3860594B1 (https=) |
| JP (2) | JP7524167B2 (https=) |
| KR (1) | KR102902972B1 (https=) |
| CN (1) | CN113286587A (https=) |
| AU (1) | AU2019354784B2 (https=) |
| BR (1) | BR112021006132A2 (https=) |
| CA (1) | CA3114434A1 (https=) |
| ES (1) | ES3057657T3 (https=) |
| IL (1) | IL281965B1 (https=) |
| MA (1) | MA53817A (https=) |
| MX (1) | MX2021003606A (https=) |
| WO (1) | WO2020072814A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117017985A (zh) | 2016-10-13 | 2023-11-10 | 特拉维尔治疗公司 | 用于治疗肾脏疾病或病症的联苯磺酰胺化合物 |
| WO2022246200A1 (en) * | 2021-05-21 | 2022-11-24 | Travere Therapeutics, Inc. | Methods of treating kidney diseases or disorders |
| WO2022266370A1 (en) * | 2021-06-17 | 2022-12-22 | Aria Pharmaceuticals, Inc. | Sparsentan for treating idiopathic pulmonary fibrosis |
| JP2025183466A (ja) * | 2022-11-11 | 2025-12-17 | 株式会社アークメディスン | 化合物、エンドセリンａ受容体拮抗剤、アンジオテンシンｉｉタイプ１受容体拮抗剤及び医薬組成物 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018071784A1 (en) * | 2016-10-13 | 2018-04-19 | Retrophin, Inc. | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| HUP0104634A3 (en) | 1998-07-06 | 2002-11-28 | Bristol Myers Squibb Co | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| ATE339417T1 (de) | 1999-12-15 | 2006-10-15 | Bristol Myers Squibb Co | Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten |
| WO2010114801A1 (en) | 2009-03-31 | 2010-10-07 | Ligand Pharmaceuticals Inc. | Oral formulations of diphenylsulfonamide endothelin and angiotensin ii receptor agonists to treat elevated blood pressure and diabetic nephropathy |
| WO2010135350A2 (en) | 2009-05-20 | 2010-11-25 | Pharmacopeia, Llc | Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist |
| US9719981B2 (en) | 2012-08-17 | 2017-08-01 | Father Flanagan's Boys' Home | RAC1 inhibitors for the treatment of alport glomerular disease |
| CA2958585C (en) * | 2014-08-21 | 2024-01-09 | Stealth Biotherapeutics Corp | Use of peptide d-arg-2',6'-dmt-lys-phe-nh2 for the treatment of alport syndrome |
| EP3515501A1 (en) * | 2016-09-19 | 2019-07-31 | Aten Porus Lifesciences | Cyclodextrin based polymers, methods, compositions and applications thereof |
| US20220048900A1 (en) | 2018-12-21 | 2022-02-17 | Travere Therapuetics, Inc. | Amorphous sparsentan compositions |
-
2019
- 2019-10-03 MA MA053817A patent/MA53817A/fr unknown
- 2019-10-03 BR BR112021006132-0A patent/BR112021006132A2/pt unknown
- 2019-10-03 EP EP19791401.3A patent/EP3860594B1/en active Active
- 2019-10-03 IL IL281965A patent/IL281965B1/en unknown
- 2019-10-03 JP JP2021518888A patent/JP7524167B2/ja active Active
- 2019-10-03 MX MX2021003606A patent/MX2021003606A/es unknown
- 2019-10-03 WO PCT/US2019/054559 patent/WO2020072814A1/en not_active Ceased
- 2019-10-03 AU AU2019354784A patent/AU2019354784B2/en active Active
- 2019-10-03 US US16/592,633 patent/US11207299B2/en active Active
- 2019-10-03 CN CN201980079773.4A patent/CN113286587A/zh active Pending
- 2019-10-03 KR KR1020217010358A patent/KR102902972B1/ko active Active
- 2019-10-03 ES ES19791401T patent/ES3057657T3/es active Active
- 2019-10-03 CA CA3114434A patent/CA3114434A1/en active Pending
-
2024
- 2024-07-17 JP JP2024114026A patent/JP2024133735A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018071784A1 (en) * | 2016-10-13 | 2018-04-19 | Retrophin, Inc. | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
Non-Patent Citations (3)
| Title |
|---|
| FRANK T.L. VAN DER LOOP ET AL,, AUTOSOMAL DOMINANT ALPORT SYNDROME CAUSED BY A COL4A3 SPLICE SITE MUTATION, 1 November 2000 (2000-11-01) * |
| MEEHAN, DANIEL T ET AL.,, ENDOTHELIN-1 MEDIATED INDUCTION OF EXTRACELLULAR MATRIX GENES IN STRIAL MARGINAL CELLS UNDERLIES STRIAL PATHOLOGY IN ALPORT MICE, 21 August 2016 (2016-08-21) * |
| SHARON G. ADLER ET AL,, GLOMERULAR TYPE IV COLLAGEN IN PATIENTS WITH DIABETIC NEPHROPATHY WITH AND WITHOUT ADDITIONAL GLOMERULAR DISEASE, 1 May 2000 (2000-05-01) * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7524167B2 (ja) | 2024-07-29 |
| MX2021003606A (es) | 2021-08-16 |
| BR112021006132A2 (pt) | 2021-07-20 |
| US20200147050A1 (en) | 2020-05-14 |
| JP2024133735A (ja) | 2024-10-02 |
| MA53817A (fr) | 2021-08-11 |
| CN113286587A (zh) | 2021-08-20 |
| EP3860594B1 (en) | 2025-10-01 |
| CA3114434A1 (en) | 2020-04-09 |
| AU2019354784A1 (en) | 2021-04-15 |
| IL281965A (en) | 2021-05-31 |
| WO2020072814A1 (en) | 2020-04-09 |
| JP2022514152A (ja) | 2022-02-10 |
| AU2019354784B2 (en) | 2025-07-10 |
| US11207299B2 (en) | 2021-12-28 |
| ES3057657T3 (en) | 2026-03-03 |
| KR20210081338A (ko) | 2021-07-01 |
| KR102902972B1 (ko) | 2025-12-22 |
| EP3860594A1 (en) | 2021-08-11 |
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