IL280101B2 - Peptide compounds and their therapeutic uses - Google Patents

Peptide compounds and their therapeutic uses

Info

Publication number
IL280101B2
IL280101B2 IL280101A IL28010121A IL280101B2 IL 280101 B2 IL280101 B2 IL 280101B2 IL 280101 A IL280101 A IL 280101A IL 28010121 A IL28010121 A IL 28010121A IL 280101 B2 IL280101 B2 IL 280101B2
Authority
IL
Israel
Prior art keywords
peptide
seq
amino acid
present
amino acids
Prior art date
Application number
IL280101A
Other languages
English (en)
Hebrew (he)
Other versions
IL280101A (en
IL280101B1 (en
Inventor
Ovadia Eran
Ben-Shimon Avi
Original Assignee
Immunity Pharma Ltd
Ovadia Eran
Avi Ben Shimon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=69141375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL280101(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunity Pharma Ltd, Ovadia Eran, Avi Ben Shimon filed Critical Immunity Pharma Ltd
Publication of IL280101A publication Critical patent/IL280101A/en
Publication of IL280101B1 publication Critical patent/IL280101B1/en
Publication of IL280101B2 publication Critical patent/IL280101B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IL280101A 2018-07-11 2019-07-10 Peptide compounds and their therapeutic uses IL280101B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL26055518 2018-07-11
PCT/IL2019/050774 WO2020012478A2 (en) 2018-07-11 2019-07-10 Peptide compounds and therapeutic uses of same

Publications (3)

Publication Number Publication Date
IL280101A IL280101A (en) 2021-03-01
IL280101B1 IL280101B1 (en) 2025-01-01
IL280101B2 true IL280101B2 (en) 2025-05-01

Family

ID=69141375

Family Applications (2)

Application Number Title Priority Date Filing Date
IL280101A IL280101B2 (en) 2018-07-11 2019-07-10 Peptide compounds and their therapeutic uses
IL317252A IL317252A (en) 2018-07-11 2019-07-10 Peptide compounds and their therapeutic uses

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL317252A IL317252A (en) 2018-07-11 2019-07-10 Peptide compounds and their therapeutic uses

Country Status (21)

Country Link
US (2) US11912790B2 (enExample)
EP (2) EP4566617A3 (enExample)
JP (2) JP7395517B2 (enExample)
KR (1) KR102880543B1 (enExample)
CN (1) CN112351989B (enExample)
AU (2) AU2019300567B2 (enExample)
BR (1) BR112020024748A2 (enExample)
CA (1) CA3100961A1 (enExample)
CO (1) CO2021001290A2 (enExample)
EA (1) EA202190249A1 (enExample)
ES (1) ES3026158T3 (enExample)
HR (1) HRP20250746T1 (enExample)
HU (1) HUE072141T2 (enExample)
IL (2) IL280101B2 (enExample)
MX (1) MX2021000264A (enExample)
PL (1) PL3820882T3 (enExample)
RS (1) RS66946B1 (enExample)
SG (1) SG11202012773QA (enExample)
UA (1) UA130911C2 (enExample)
WO (1) WO2020012478A2 (enExample)
ZA (1) ZA202100587B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7395517B2 (ja) 2018-07-11 2023-12-11 イミュニティ ファルマ リミテッド ペプチド化合物およびその治療的用途
IL272074B2 (en) * 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same

Citations (5)

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US20040204340A1 (en) * 2003-04-11 2004-10-14 Guilford Pharmaceuticals, Inc. Polyprolyl inhibitors of cyclophilin
WO2006021954A2 (en) * 2004-08-23 2006-03-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Peptide inhibitors for mediating stress responses
US20070197444A1 (en) * 2006-02-17 2007-08-23 Nastech Pharmaceutical Company Inc. Phage displayed cell binding peptides
US20160038571A1 (en) * 2014-08-06 2016-02-11 Brown University Method and compositions for treatment of calcineurin-related diseases
US10011829B2 (en) * 2010-07-16 2018-07-03 Avantgen, Inc. Peptides and uses thereof

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NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
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US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
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US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US6432407B1 (en) * 1995-12-12 2002-08-13 Takara Shuzo Co., Ltd. Antigenic protein originating in malassezia
WO1997044447A2 (en) * 1996-05-03 1997-11-27 President And Fellows Of Harvard College Transcriptional activation system, activators, and uses therefor
US6861256B2 (en) * 1997-05-15 2005-03-01 The General Hospital Corporation Therapeutic and diagnostic tools for impaired glucose tolerance conditions
GB9711148D0 (en) * 1997-05-31 1997-07-23 Peptide Therapeutics Ltd Human MAFA
EP0928968A1 (en) 1998-01-12 1999-07-14 Universität Basel Screening method for apoptosis and necrosis
US20090087878A9 (en) * 1999-05-06 2009-04-02 La Rosa Thomas J Nucleic acid molecules associated with plants
CA2443314C (en) 2001-04-03 2006-03-21 The Board Of Trustees Of The Leland Stanford Junior University Method of imaging cell death in vivo
EP1843779A2 (en) * 2005-02-01 2007-10-17 Attenuon, LLC Compositions containing the anti-angiogenic phscn-peptide
JP2007228925A (ja) * 2006-03-02 2007-09-13 Kaneka Corp 新規酸化酵素及びそれを用いたグリオキサールの製造方法
JP5351495B2 (ja) * 2008-11-05 2013-11-27 国立大学法人東北大学 スーパーオキシドディスムターゼを用いるアセトアルデヒド分解方法
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WO2017011338A1 (en) 2015-07-10 2017-01-19 President And Fellows Of Harvard College Sortase-mediated coupling of immunogenic polysaccharide-protein conjugates and their use
JP7395517B2 (ja) 2018-07-11 2023-12-11 イミュニティ ファルマ リミテッド ペプチド化合物およびその治療的用途
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040204340A1 (en) * 2003-04-11 2004-10-14 Guilford Pharmaceuticals, Inc. Polyprolyl inhibitors of cyclophilin
WO2006021954A2 (en) * 2004-08-23 2006-03-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Peptide inhibitors for mediating stress responses
US20070197444A1 (en) * 2006-02-17 2007-08-23 Nastech Pharmaceutical Company Inc. Phage displayed cell binding peptides
US10011829B2 (en) * 2010-07-16 2018-07-03 Avantgen, Inc. Peptides and uses thereof
US20160038571A1 (en) * 2014-08-06 2016-02-11 Brown University Method and compositions for treatment of calcineurin-related diseases

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* Cited by examiner, † Cited by third party
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MIRGORODSKAYA O A ET AL,, BRADYKININ DEGRADATION PATHWAYS IN HUMAN BLOOD PLASMA, 3 August 1992 (1992-08-03) *
NOMIZU M ET AL,, CONVULSANT PEPTIDES RELATED TO CORTICOTROPIN-RELEASING FACTOR (CRF), 29 December 1989 (1989-12-29) *
RACHEL DIMRI ET AL,, SPECIFIC INHIBITION OF GLUCOCORTICOID-INDUCED THYMOCYTE APOPTOSIS BY SUBSTANCE P, 1 March 2000 (2000-03-01) *

Also Published As

Publication number Publication date
AU2024278477B2 (en) 2026-07-09
WO2020012478A2 (en) 2020-01-16
UA130911C2 (uk) 2026-06-17
IL317252A (en) 2025-01-01
SG11202012773QA (en) 2021-01-28
BR112020024748A2 (pt) 2021-03-23
JP2021531246A (ja) 2021-11-18
HRP20250746T1 (hr) 2025-08-15
CN112351989B (zh) 2024-03-26
EP4566617A2 (en) 2025-06-11
KR102880543B1 (ko) 2025-11-04
JP7395517B2 (ja) 2023-12-11
AU2019300567B2 (en) 2024-09-19
EP4566617A3 (en) 2025-10-01
CN112351989A (zh) 2021-02-09
EA202190249A1 (ru) 2021-05-21
WO2020012478A3 (en) 2020-02-20
HUE072141T2 (hu) 2025-10-28
PL3820882T3 (pl) 2025-08-11
US11912790B2 (en) 2024-02-27
US20210261615A1 (en) 2021-08-26
ES3026158T3 (en) 2025-06-10
US20240190919A1 (en) 2024-06-13
AU2024278477A1 (en) 2025-01-30
IL280101A (en) 2021-03-01
MX2021000264A (es) 2021-05-12
CA3100961A1 (en) 2020-01-16
EP3820882A2 (en) 2021-05-19
CO2021001290A2 (es) 2021-02-26
AU2019300567A1 (en) 2021-02-25
ZA202100587B (en) 2022-07-27
RS66946B1 (sr) 2025-07-31
EP3820882B1 (en) 2025-04-02
IL280101B1 (en) 2025-01-01
JP2024026217A (ja) 2024-02-28
JP7682248B2 (ja) 2025-05-23
KR20210045397A (ko) 2021-04-26
EP3820882C0 (en) 2025-04-02

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