IL274504A - 2ACSS inhibitors and methods of their use - Google Patents
2ACSS inhibitors and methods of their useInfo
- Publication number
- IL274504A IL274504A IL274504A IL27450420A IL274504A IL 274504 A IL274504 A IL 274504A IL 274504 A IL274504 A IL 274504A IL 27450420 A IL27450420 A IL 27450420A IL 274504 A IL274504 A IL 274504A
- Authority
- IL
- Israel
- Prior art keywords
- methods
- acss2
- inhibitors
- acss2 inhibitors
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4152—1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
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- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- Health & Medical Sciences (AREA)
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- Diabetes (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762586195P | 2017-11-15 | 2017-11-15 | |
PCT/IL2018/051232 WO2019097515A1 (fr) | 2017-11-15 | 2018-11-15 | Inhibiteurs d'acss2 et leurs procédés d'utilisation |
Publications (1)
Publication Number | Publication Date |
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IL274504A true IL274504A (en) | 2020-06-30 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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IL274504A IL274504A (en) | 2017-11-15 | 2020-05-06 | 2ACSS inhibitors and methods of their use |
Country Status (13)
Country | Link |
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US (1) | US10851064B2 (fr) |
EP (1) | EP3710430B1 (fr) |
JP (1) | JP7217752B2 (fr) |
KR (1) | KR20200089291A (fr) |
CN (1) | CN111566092A (fr) |
AU (1) | AU2018370096B2 (fr) |
BR (1) | BR112020009729A2 (fr) |
CA (1) | CA3080675A1 (fr) |
IL (1) | IL274504A (fr) |
MA (1) | MA50912A (fr) |
MX (1) | MX2020004994A (fr) |
SG (1) | SG11202004318PA (fr) |
WO (1) | WO2019097515A1 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3111627A1 (fr) * | 2018-09-26 | 2020-04-02 | The Trustees Of The University Of Pennsylvania | Compositions et methodes pour inhiber acss2 |
US11739078B2 (en) | 2019-02-22 | 2023-08-29 | Insilico Medicine Ip Limited | Methods of inhibiting kinases |
CA3136083A1 (fr) * | 2019-05-14 | 2020-11-19 | Metabomed Ltd | Inhibiteurs d'acss2 et leurs procedes d'utilisation |
WO2020252407A1 (fr) * | 2019-06-12 | 2020-12-17 | The Wistar Institute | Inhibiteurs de l'acétyl-coa synthétase 2 (acss2) et leurs procédés d'utilisation |
WO2021004389A1 (fr) * | 2019-07-05 | 2021-01-14 | 司龙龙 | Virus ciblé protéolytique, vaccin vivant de celui-ci, procédé de préparation correspondant et son utilisation |
CR20220316A (es) | 2019-12-06 | 2022-10-07 | Vertex Pharma | Tetrahidrofuranos sustituidos como moduladores de canales de sodio |
CN117794920A (zh) | 2021-06-04 | 2024-03-29 | 沃泰克斯药物股份有限公司 | N-(羟烷基(杂)芳基)四氢呋喃甲酰胺作为钠通道调节剂 |
CN113912596B (zh) * | 2021-11-25 | 2022-12-02 | 江苏科技大学 | 一种基于苯并噻唑母体的钯离子检测荧光探针及其制备方法与应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3905997A (en) * | 1974-06-21 | 1975-09-16 | Warner Lambert Co | 3-Aryl-5-oxo-2-pyrazoline-4-carboxanilides and process therefor |
US4134987A (en) * | 1976-01-14 | 1979-01-16 | Huppatz John L | Compounds and compositions |
US4207317A (en) * | 1978-03-13 | 1980-06-10 | Ciba-Geigy Corporation | 1-Aryl-4-carbamoyl-pyrazolin-5-ones |
JPH11291635A (ja) * | 1998-04-06 | 1999-10-26 | Mitsubishi Paper Mills Ltd | 感熱記録材料 |
AR034897A1 (es) | 2001-08-07 | 2004-03-24 | Hoffmann La Roche | Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos |
BR0212510A (pt) | 2001-09-14 | 2004-08-24 | Methylgene Inc | Inibidor de histona desacetilase, composto e composição |
WO2007026215A1 (fr) | 2005-08-29 | 2007-03-08 | Glenmark Pharmaceuticals S.A. | Dérivés de pyrazole tels que les ligands du récepteur de cannabinoïde, compositions pharmaceutiques les contenant et procédés pour leur préparation |
WO2008121861A2 (fr) | 2007-03-28 | 2008-10-09 | Xenon Pharmaceuticals Inc. | Composés à base de pyrazole et de pyrrole utiles dans le traitement de troubles du métabolisme du fer |
EP2569287B1 (fr) | 2010-05-12 | 2014-07-09 | Vertex Pharmaceuticals Inc. | Composés utilisables en tant qu'inhibiteurs de la kinase atr |
WO2013159224A1 (fr) * | 2012-04-25 | 2013-10-31 | University Of Manitoba | Dérivés 2-carbamo(thio)yl-1,3-dioxopropylés en thérapie du cancer |
US10040767B2 (en) | 2014-05-15 | 2018-08-07 | Peloton Therapeutics, Inc. | Benzimidazole derivatives and uses thereof |
-
2018
- 2018-11-15 BR BR112020009729-2A patent/BR112020009729A2/pt active Search and Examination
- 2018-11-15 AU AU2018370096A patent/AU2018370096B2/en not_active Expired - Fee Related
- 2018-11-15 JP JP2020545015A patent/JP7217752B2/ja active Active
- 2018-11-15 EP EP18877721.3A patent/EP3710430B1/fr active Active
- 2018-11-15 MA MA050912A patent/MA50912A/fr unknown
- 2018-11-15 MX MX2020004994A patent/MX2020004994A/es unknown
- 2018-11-15 WO PCT/IL2018/051232 patent/WO2019097515A1/fr unknown
- 2018-11-15 CA CA3080675A patent/CA3080675A1/fr active Pending
- 2018-11-15 CN CN201880083277.1A patent/CN111566092A/zh active Pending
- 2018-11-15 KR KR1020207016936A patent/KR20200089291A/ko not_active Application Discontinuation
- 2018-11-15 SG SG11202004318PA patent/SG11202004318PA/en unknown
-
2019
- 2019-05-14 US US16/411,168 patent/US10851064B2/en active Active
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2020
- 2020-05-06 IL IL274504A patent/IL274504A/en unknown
Also Published As
Publication number | Publication date |
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MA50912A (fr) | 2020-09-23 |
SG11202004318PA (en) | 2020-06-29 |
BR112020009729A2 (pt) | 2020-11-03 |
CN111566092A (zh) | 2020-08-21 |
JP2021503013A (ja) | 2021-02-04 |
US20190263758A1 (en) | 2019-08-29 |
CA3080675A1 (fr) | 2019-05-23 |
AU2018370096A1 (en) | 2020-06-11 |
EP3710430B1 (fr) | 2024-07-03 |
MX2020004994A (es) | 2020-10-12 |
EP3710430A1 (fr) | 2020-09-23 |
JP7217752B2 (ja) | 2023-02-03 |
US10851064B2 (en) | 2020-12-01 |
WO2019097515A1 (fr) | 2019-05-23 |
AU2018370096B2 (en) | 2023-08-31 |
EP3710430A4 (fr) | 2021-06-23 |
KR20200089291A (ko) | 2020-07-24 |
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