IL272320A - Methods and devices for the detection of anticoagulants in plasma and blood - Google Patents
Methods and devices for the detection of anticoagulants in plasma and bloodInfo
- Publication number
- IL272320A IL272320A IL272320A IL27232020A IL272320A IL 272320 A IL272320 A IL 272320A IL 272320 A IL272320 A IL 272320A IL 27232020 A IL27232020 A IL 27232020A IL 272320 A IL272320 A IL 272320A
- Authority
- IL
- Israel
- Prior art keywords
- anticoagulants
- plasma
- detection
- methods
- devices
- Prior art date
Links
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 229940127219 anticoagulant drug Drugs 0.000 title 1
- 239000008280 blood Substances 0.000 title 1
- 210000004369 blood Anatomy 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
- B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/088—Passive control of flow resistance by specific surface properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Fluid Mechanics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762538618P | 2017-07-28 | 2017-07-28 | |
| US201862699665P | 2018-07-17 | 2018-07-17 | |
| PCT/US2018/043973 WO2019023508A1 (en) | 2017-07-28 | 2018-07-26 | METHODS AND DEVICES FOR DETECTION OF ANTICOAGULANTS IN PLASMA AND WHOLE BLOOD |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL272320A true IL272320A (en) | 2020-03-31 |
Family
ID=63405342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL272320A IL272320A (en) | 2017-07-28 | 2020-01-28 | Methods and devices for the detection of anticoagulants in plasma and blood |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20190111431A1 (enExample) |
| EP (1) | EP3658920A1 (enExample) |
| JP (1) | JP7214712B2 (enExample) |
| KR (1) | KR20200034749A (enExample) |
| CN (1) | CN111094990A (enExample) |
| AU (1) | AU2018307799A1 (enExample) |
| CA (1) | CA3071295A1 (enExample) |
| IL (1) | IL272320A (enExample) |
| SG (1) | SG11202000688UA (enExample) |
| WO (1) | WO2019023508A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2750839C1 (ru) * | 2020-05-18 | 2021-07-05 | Общество с ограниченной ответственностью "Меднорд-Техника" (ООО "Меднорд-Т") | Устройство и способ экспресс-оценки агрегационной активности форменных элементов крови |
| US20220283190A1 (en) * | 2021-03-08 | 2022-09-08 | Galit H. Frydman | Methods and devices for detection of coagulation impairment |
| CN113945551A (zh) * | 2021-10-19 | 2022-01-18 | 重庆医科大学附属永川医院 | 一种血小板功能的微流控分析检测模型 |
| CN114558629B (zh) * | 2022-03-03 | 2024-06-04 | 四川微康朴澜医疗科技有限责任公司 | 一种微流控式血栓弹力分析检测试剂盒 |
| IL319816A (en) | 2022-09-30 | 2025-05-01 | Coagulo Medical Tech Inc | Modular microfluidic cartridge testing device, useful for point-of-care medical diagnostics and other applications |
| WO2025132678A1 (en) * | 2023-12-19 | 2025-06-26 | F. Hoffmann-La Roche Ag | Qualitative test for direct oral anticoagulants (doacs) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2040073A1 (en) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Microfluidic device and method for fluid clotting time determination |
| WO2013067536A1 (en) | 2011-11-04 | 2013-05-10 | Massachusetts Institute Of Technology | Multi-parameter thrombotic assay apparatus, systems, and methods |
| US9709579B2 (en) | 2012-06-27 | 2017-07-18 | Colorado School Of Mines | Microfluidic flow assay and methods of use |
| US20140038204A1 (en) | 2012-07-31 | 2014-02-06 | Baxter Healthcare S.A. | Selective measurement of active human protease coagulation factors |
| US9562914B2 (en) * | 2013-10-16 | 2017-02-07 | President And Fellows Of Harvard College | Microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation |
| EP3191836B1 (en) | 2014-09-09 | 2022-11-23 | Perosphere Technologies Inc. | Microfluid chip-based, universal coagulation assay |
-
2018
- 2018-07-26 CN CN201880059719.9A patent/CN111094990A/zh active Pending
- 2018-07-26 JP JP2020504364A patent/JP7214712B2/ja active Active
- 2018-07-26 EP EP18760075.4A patent/EP3658920A1/en not_active Withdrawn
- 2018-07-26 CA CA3071295A patent/CA3071295A1/en active Pending
- 2018-07-26 WO PCT/US2018/043973 patent/WO2019023508A1/en not_active Ceased
- 2018-07-26 US US16/046,816 patent/US20190111431A1/en not_active Abandoned
- 2018-07-26 SG SG11202000688UA patent/SG11202000688UA/en unknown
- 2018-07-26 KR KR1020207004767A patent/KR20200034749A/ko not_active Abandoned
- 2018-07-26 AU AU2018307799A patent/AU2018307799A1/en not_active Abandoned
-
2020
- 2020-01-28 IL IL272320A patent/IL272320A/en unknown
-
2023
- 2023-01-25 US US18/159,281 patent/US20230166255A1/en not_active Abandoned
- 2023-01-25 US US18/159,276 patent/US20230158498A1/en not_active Abandoned
- 2023-01-25 US US18/159,283 patent/US20230158499A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019023508A1 (en) | 2019-01-31 |
| KR20200034749A (ko) | 2020-03-31 |
| US20190111431A1 (en) | 2019-04-18 |
| JP2020529593A (ja) | 2020-10-08 |
| AU2018307799A1 (en) | 2020-02-13 |
| JP7214712B2 (ja) | 2023-01-30 |
| SG11202000688UA (en) | 2020-02-27 |
| US20230166255A1 (en) | 2023-06-01 |
| CA3071295A1 (en) | 2019-01-31 |
| EP3658920A1 (en) | 2020-06-03 |
| US20230158499A1 (en) | 2023-05-25 |
| US20230158498A1 (en) | 2023-05-25 |
| CN111094990A (zh) | 2020-05-01 |
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