IL262195B2 - Methods and preparations for improving the anti-inflammatory effects of interleukin 10 - Google Patents
Methods and preparations for improving the anti-inflammatory effects of interleukin 10Info
- Publication number
- IL262195B2 IL262195B2 IL262195A IL26219518A IL262195B2 IL 262195 B2 IL262195 B2 IL 262195B2 IL 262195 A IL262195 A IL 262195A IL 26219518 A IL26219518 A IL 26219518A IL 262195 B2 IL262195 B2 IL 262195B2
- Authority
- IL
- Israel
- Prior art keywords
- composition
- vector
- promoters
- promoter
- inflammation
- Prior art date
Links
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| US201662326082P | 2016-04-22 | 2016-04-22 | |
| PCT/US2017/028755 WO2017184933A1 (en) | 2016-04-22 | 2017-04-21 | Methods and compositions to enhance the anti-inflammatory effects of interleukin 10 |
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| IL262195A IL262195A (en) | 2018-11-29 |
| IL262195B1 IL262195B1 (en) | 2023-05-01 |
| IL262195B2 true IL262195B2 (en) | 2023-09-01 |
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| SI3021873T1 (sl) | 2013-07-18 | 2018-12-31 | Xalud Therapeutics, Inc. | Sestavek za zdravljenje vnetne sklepne bolezni |
| CA3087238A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
| EP3803866A4 (en) | 2018-05-24 | 2022-03-16 | Nureva Inc. | METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS |
| CN111989068B (zh) | 2018-05-24 | 2024-10-25 | 塞拉尼斯伊娃高性能聚合物公司 | 用于持续释放大分子药物化合物的可植入器件 |
| CN112779285B (zh) * | 2019-11-11 | 2023-01-06 | 百奥赛图(北京)医药科技股份有限公司 | 人源化il-10和il-10ra基因改造动物的构建方法和应用 |
| EP4329734A4 (en) | 2021-04-26 | 2025-04-02 | Celanese EVA Performance Polymers LLC | Implantable device for the delayed release of a macromolecular drug compound |
| KR102466921B1 (ko) * | 2021-06-29 | 2022-11-14 | 주식회사 오에이티씨 | 인터루킨-4를 암호화하는 유전자를 포함하는 신경병증성 통증의 예방 또는 치료용 약학적 조성물 |
| WO2023114958A1 (en) * | 2021-12-16 | 2023-06-22 | Xalud Therapeutics, Inc. | Dosing regimen for il-10 encoding expression construct |
Citations (4)
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|---|---|---|---|---|
| US5716804A (en) * | 1995-04-19 | 1998-02-10 | Schering Corporation | Mammalian interleukin-10 (IL-10) super-activating receptors; and variants |
| US20090035256A1 (en) * | 2005-05-31 | 2009-02-05 | Sommer Jurg M | Mutant Il-10 |
| US20120058102A1 (en) * | 2010-03-29 | 2012-03-08 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| WO2015009955A1 (en) * | 2013-07-18 | 2015-01-22 | Xalud Therapeutics, Inc. | Methods for the treatment of inflammatory joint disease |
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| US7261882B2 (en) * | 2003-06-23 | 2007-08-28 | Reagents Of The University Of Colorado | Methods for treating neuropathic pain by administering IL-10 polypeptides |
| EP2550359B1 (en) * | 2010-03-23 | 2017-08-09 | Intrexon Corporation | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
| WO2013103966A1 (en) * | 2012-01-06 | 2013-07-11 | The Regents Of The University Of Colorado, A Body Corporate | Methods for the treatment of multiple sclerosis and other demyelinating disorders |
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- 2017-04-21 IL IL262195A patent/IL262195B2/en unknown
- 2017-04-21 WO PCT/US2017/028755 patent/WO2017184933A1/en not_active Ceased
- 2017-04-21 EP EP17786683.7A patent/EP3445849B1/en active Active
- 2017-04-21 JP JP2018555141A patent/JP7163189B2/ja active Active
-
2022
- 2022-08-04 JP JP2022124716A patent/JP2022169585A/ja active Pending
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2024
- 2024-04-29 US US18/648,678 patent/US20240352089A1/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716804A (en) * | 1995-04-19 | 1998-02-10 | Schering Corporation | Mammalian interleukin-10 (IL-10) super-activating receptors; and variants |
| US20090035256A1 (en) * | 2005-05-31 | 2009-02-05 | Sommer Jurg M | Mutant Il-10 |
| US20120058102A1 (en) * | 2010-03-29 | 2012-03-08 | The Trustees Of The University Of Pennsylvania | Pharmacologically induced transgene ablation system |
| WO2015009955A1 (en) * | 2013-07-18 | 2015-01-22 | Xalud Therapeutics, Inc. | Methods for the treatment of inflammatory joint disease |
Non-Patent Citations (1)
| Title |
|---|
| CREPALDI ET AL.,, UP-REGULATION OF IL-10R1 EXPRESSION IS REQUIRED TO RENDER HUMAN NEUTROPHILS FULLY RESPONSIVE TO IL-10, 1 January 2001 (2001-01-01) * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3445849A4 (en) | 2019-09-25 |
| RU2018140988A (ru) | 2020-05-22 |
| JP2019518003A (ja) | 2019-06-27 |
| WO2017184933A1 (en) | 2017-10-26 |
| KR102430455B1 (ko) | 2022-08-05 |
| JP2022169585A (ja) | 2022-11-09 |
| US20240352089A1 (en) | 2024-10-24 |
| AU2017252327A1 (en) | 2018-11-15 |
| CN109477085B (zh) | 2023-08-01 |
| EP3445849B1 (en) | 2024-06-05 |
| JP7163189B2 (ja) | 2022-10-31 |
| US20190112354A1 (en) | 2019-04-18 |
| EP3445849A1 (en) | 2019-02-27 |
| KR20190021211A (ko) | 2019-03-05 |
| DK3445849T3 (da) | 2024-08-05 |
| IL262195B1 (en) | 2023-05-01 |
| CA3019846A1 (en) | 2017-10-26 |
| IL262195A (en) | 2018-11-29 |
| RU2731160C2 (ru) | 2020-08-31 |
| CN109477085A (zh) | 2019-03-15 |
| AU2017252327B2 (en) | 2023-05-25 |
| RU2018140988A3 (enExample) | 2020-05-25 |
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