IL261201B - Aminobenzaimidazole derivatives - Google Patents
Aminobenzaimidazole derivativesInfo
- Publication number
- IL261201B IL261201B IL261201A IL26120118A IL261201B IL 261201 B IL261201 B IL 261201B IL 261201 A IL261201 A IL 261201A IL 26120118 A IL26120118 A IL 26120118A IL 261201 B IL261201 B IL 261201B
- Authority
- IL
- Israel
- Prior art keywords
- aminobenzimidazole derivatives
- aminobenzimidazole
- derivatives
- Prior art date
Links
- JWYUFVNJZUSCSM-UHFFFAOYSA-N 2-aminobenzimidazole Chemical class C1=CC=C2NC(N)=NC2=C1 JWYUFVNJZUSCSM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662302781P | 2016-03-02 | 2016-03-02 | |
| PCT/US2016/033841 WO2017151165A1 (en) | 2016-03-02 | 2016-05-23 | Aminobenzimidazole derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL261201A IL261201A (en) | 2018-10-31 |
| IL261201B true IL261201B (en) | 2022-01-01 |
Family
ID=59744272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL261201A IL261201B (en) | 2016-03-02 | 2018-08-16 | Aminobenzaimidazole derivatives |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20190040017A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3423439A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6768078B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN109071460B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2016394945A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3053238A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL261201B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017151165A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105980365B (zh) | 2014-02-11 | 2019-06-21 | 拜耳医药股份公司 | 作为mIDH1抑制剂的苯并咪唑-2-胺 |
| PE20170143A1 (es) | 2014-02-11 | 2017-03-19 | Bayer Pharma AG | Benzimidazol-2-aminas como inhibidores de midh1 |
| US10780080B2 (en) * | 2016-11-23 | 2020-09-22 | Translational Drug Development, Llc | Benzamide and active compound compositions and methods of use |
| US11236052B2 (en) * | 2017-09-06 | 2022-02-01 | Translational Drug Development, Llc | Aminobenzimidazole derivatives, treatments, and methods of inhibiting histone deacetylase |
| EP4373811A4 (en) | 2021-07-21 | 2025-05-21 | Carna Biosciences, Inc. | NEW 1,2-DIAMINOBENZIMIDAZOLE DERIVATIVE |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009528384A (ja) * | 2006-03-02 | 2009-08-06 | スミスクライン・ビーチャム・コーポレイション | Ｐｉ３キナーゼ阻害剤として用いるためのチアゾロン |
| JP5868851B2 (ja) * | 2009-06-23 | 2016-02-24 | ザ・トランスレーショナル・ジェノミクス・リサーチ・インスティチュート | ベンズアミド誘導体 |
| EP2715956B1 (en) * | 2011-05-27 | 2019-09-11 | Cisco Technology, Inc. | Precision timing in a data over cable service interface specification (docsis) system |
| US20150297579A1 (en) * | 2012-11-05 | 2015-10-22 | Celgene Corporation | Treatment of cancer with pomalidomide in a renally impaired subject |
| CN107921126A (zh) * | 2015-05-22 | 2018-04-17 | 转化药物开发有限责任公司 | 苯甲酰胺和活性化合物的组合物及其使用方法 |
| CN108026052B (zh) * | 2015-07-16 | 2021-10-08 | 德国癌症研究公共权益基金会 | 作为mIDH1抑制剂的5-羟烷基苯并咪唑类 |
-
2016
- 2016-05-23 CA CA3053238A patent/CA3053238A1/en active Pending
- 2016-05-23 CN CN201680085289.9A patent/CN109071460B/zh not_active Expired - Fee Related
- 2016-05-23 WO PCT/US2016/033841 patent/WO2017151165A1/en not_active Ceased
- 2016-05-23 US US16/074,706 patent/US20190040017A1/en not_active Abandoned
- 2016-05-23 AU AU2016394945A patent/AU2016394945A1/en not_active Abandoned
- 2016-05-23 JP JP2018546039A patent/JP6768078B2/ja active Active
- 2016-05-23 EP EP16892907.3A patent/EP3423439A4/en not_active Withdrawn
-
2018
- 2018-08-16 IL IL261201A patent/IL261201B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016394945A1 (en) | 2018-10-11 |
| CN109071460A (zh) | 2018-12-21 |
| IL261201A (en) | 2018-10-31 |
| JP6768078B2 (ja) | 2020-10-14 |
| JP2019511485A (ja) | 2019-04-25 |
| CN109071460B (zh) | 2022-08-09 |
| WO2017151165A1 (en) | 2017-09-08 |
| US20190040017A1 (en) | 2019-02-07 |
| EP3423439A1 (en) | 2019-01-09 |
| CA3053238A1 (en) | 2017-09-08 |
| EP3423439A4 (en) | 2019-08-14 |
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