IL259166A - תרכובות 4h–כרומן–4–און חדשות כמודולטורים של קינאזי חלבון - Google Patents

תרכובות 4h–כרומן–4–און חדשות כמודולטורים של קינאזי חלבון

Info

Publication number
IL259166A
IL259166A IL259166A IL25916618A IL259166A IL 259166 A IL259166 A IL 259166A IL 259166 A IL259166 A IL 259166A IL 25916618 A IL25916618 A IL 25916618A IL 259166 A IL259166 A IL 259166A
Authority
IL
Israel
Prior art keywords
chromen
modulators
novel
compounds
protein kinases
Prior art date
Application number
IL259166A
Other languages
English (en)
Inventor
Muthuppalaniappan Meyyappan
Viswanadha Srikant
Babu Govindarajulu
Kumar V S Vakkalanka Swaroop
Kashinath Bhavar Prashnant
Nagarathnam Dhanapalan
Original Assignee
Rhizen Pharmaceuticals S A
Muthuppalaniappan Meyyappan
Viswanadha Srikant
Babu Govindarajulu
Kumar V S Vakkalanka Swaroop
Kashinath Bhavar Prashnant
Nagarathnam Dhanapalan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2012/036594 external-priority patent/WO2012151525A1/en
Application filed by Rhizen Pharmaceuticals S A, Muthuppalaniappan Meyyappan, Viswanadha Srikant, Babu Govindarajulu, Kumar V S Vakkalanka Swaroop, Kashinath Bhavar Prashnant, Nagarathnam Dhanapalan filed Critical Rhizen Pharmaceuticals S A
Publication of IL259166A publication Critical patent/IL259166A/he

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    • C—CHEMISTRY; METALLURGY
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    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
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    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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  • Urology & Nephrology (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
IL259166A 2011-05-04 2018-05-06 תרכובות 4h–כרומן–4–און חדשות כמודולטורים של קינאזי חלבון IL259166A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1542CH2011 2011-05-04
PCT/US2012/036594 WO2012151525A1 (en) 2011-05-04 2012-05-04 Novel compounds as modulators of protein kinases

Publications (1)

Publication Number Publication Date
IL259166A true IL259166A (he) 2018-06-28

Family

ID=50023000

Family Applications (3)

Application Number Title Priority Date Filing Date
IL229235A IL229235B (he) 2011-05-04 2013-11-04 נגזרות של h4–כרומן–4–און כמודולטורים של חלבוני קינאז
IL243729A IL243729B (he) 2011-05-04 2016-01-21 תרכובות h4–כרומין–4–און חדשות כמודולאטורים חדשים של חלבוני קינאז
IL259166A IL259166A (he) 2011-05-04 2018-05-06 תרכובות 4h–כרומן–4–און חדשות כמודולטורים של קינאזי חלבון

Family Applications Before (2)

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IL229235A IL229235B (he) 2011-05-04 2013-11-04 נגזרות של h4–כרומן–4–און כמודולטורים של חלבוני קינאז
IL243729A IL243729B (he) 2011-05-04 2016-01-21 תרכובות h4–כרומין–4–און חדשות כמודולאטורים חדשים של חלבוני קינאז

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IL229235A0 (he) 2014-01-30
IL243729A0 (he) 2016-04-21
IL243729B (he) 2020-09-30

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