IL25505A - Aminothiophene derivatives and process for their manufacture - Google Patents
Aminothiophene derivatives and process for their manufactureInfo
- Publication number
- IL25505A IL25505A IL25505A IL2550566A IL25505A IL 25505 A IL25505 A IL 25505A IL 25505 A IL25505 A IL 25505A IL 2550566 A IL2550566 A IL 2550566A IL 25505 A IL25505 A IL 25505A
- Authority
- IL
- Israel
- Prior art keywords
- thiophene
- anilino
- carboxylic acid
- melting point
- cyano
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEF0045788 | 1965-04-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL25505A true IL25505A (en) | 1970-02-19 |
Family
ID=7100669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL25505A IL25505A (en) | 1965-04-10 | 1966-03-31 | Aminothiophene derivatives and process for their manufacture |
Country Status (13)
Country | Link |
---|---|
US (1) | US3445473A (pt) |
AT (3) | AT263761B (pt) |
BE (1) | BE679374A (pt) |
BR (1) | BR6678492D0 (pt) |
CH (2) | CH547816A (pt) |
DK (1) | DK121127B (pt) |
ES (1) | ES325278A1 (pt) |
FR (1) | FR5539M (pt) |
GB (1) | GB1133850A (pt) |
IL (1) | IL25505A (pt) |
NL (1) | NL6604742A (pt) |
NO (1) | NO118669B (pt) |
SE (1) | SE316489B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4299968A (en) * | 1973-12-03 | 1981-11-10 | Hoffmann-La Roche Inc. | Novel thiophene compounds |
US4360681A (en) * | 1973-12-03 | 1982-11-23 | Hoffmann-La Roche Inc. | Novel thiophene compounds |
US4428963A (en) | 1976-08-23 | 1984-01-31 | Hoffmann-La Roche Inc. | Novel thiophene derivatives |
US4317915A (en) * | 1976-08-23 | 1982-03-02 | Hoffmann-La Roche Inc. | Novel thiophene derivatives |
YU118379A (en) * | 1978-05-24 | 1983-02-28 | Byk Gulden Lomberg Chemischefa | Process for preparing phenylaminothiophene acetic acid |
DE3861268D1 (de) * | 1987-07-07 | 1991-01-24 | Shell Int Research | Verfahren zur herstellung von thiophenderivaten. |
US5166346A (en) * | 1987-12-11 | 1992-11-24 | Hoechst Aktiengesellschaft | Process for the preparation of thiophene derivatives and also new dihydrothiophene 1-oxides |
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
JPH08510451A (ja) * | 1993-05-13 | 1996-11-05 | ネオルックス コーポレイション | 異常増殖性平滑筋細胞に関連した病因の予防及び治療 |
US6136984A (en) * | 1996-04-22 | 2000-10-24 | Novo Nordisk A/S | Solid phase and combinatorial synthesis of substituted thiophenes and of arrays of substituted thiophenes |
AU6959898A (en) | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
US6613083B2 (en) | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
JP7323913B2 (ja) * | 2019-04-12 | 2023-08-09 | 国立大学法人 筑波大学 | 睡眠誘導剤である複素環化合物 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3097206A (en) * | 1962-03-19 | 1963-07-09 | Smith Kline French Lab | Aminomethylthienyl and furyl alcohol derivatives |
-
1966
- 1966-03-30 US US538569A patent/US3445473A/en not_active Expired - Lifetime
- 1966-03-31 IL IL25505A patent/IL25505A/en unknown
- 1966-04-05 CH CH1780368A patent/CH547816A/xx not_active IP Right Cessation
- 1966-04-05 CH CH497666A patent/CH534688A/de not_active IP Right Cessation
- 1966-04-05 BR BR178492/66A patent/BR6678492D0/pt unknown
- 1966-04-06 SE SE4666/66A patent/SE316489B/xx unknown
- 1966-04-06 DK DK184666AA patent/DK121127B/da unknown
- 1966-04-06 ES ES0325278A patent/ES325278A1/es not_active Expired
- 1966-04-06 NO NO162507A patent/NO118669B/no unknown
- 1966-04-07 NL NL6604742A patent/NL6604742A/xx unknown
- 1966-04-08 AT AT142167A patent/AT263761B/de active
- 1966-04-08 AT AT338466A patent/AT260919B/de active
- 1966-04-08 AT AT142067A patent/AT263760B/de active
- 1966-04-12 GB GB15940/66A patent/GB1133850A/en not_active Expired
- 1966-04-12 BE BE679374D patent/BE679374A/xx unknown
- 1966-07-08 FR FR68769A patent/FR5539M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
NO118669B (pt) | 1970-01-26 |
FR5539M (pt) | 1967-11-13 |
AT263760B (de) | 1968-08-12 |
NL6604742A (pt) | 1966-10-11 |
CH547816A (de) | 1974-04-11 |
GB1133850A (en) | 1968-11-20 |
CH534688A (de) | 1973-03-15 |
US3445473A (en) | 1969-05-20 |
ES325278A1 (es) | 1967-04-01 |
SE316489B (pt) | 1969-10-27 |
AT263761B (de) | 1968-08-12 |
DK121127B (da) | 1971-09-13 |
BE679374A (pt) | 1966-10-12 |
BR6678492D0 (pt) | 1973-09-18 |
AT260919B (de) | 1968-03-25 |
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