IL243393A0 - Testing by a multi-protein biomarker for the detection and results of brain injury - Google Patents
Testing by a multi-protein biomarker for the detection and results of brain injuryInfo
- Publication number
- IL243393A0 IL243393A0 IL243393A IL24339315A IL243393A0 IL 243393 A0 IL243393 A0 IL 243393A0 IL 243393 A IL243393 A IL 243393A IL 24339315 A IL24339315 A IL 24339315A IL 243393 A0 IL243393 A0 IL 243393A0
- Authority
- IL
- Israel
- Prior art keywords
- outcome
- brain injury
- protein biomarker
- biomarker assay
- injury detection
- Prior art date
Links
- 238000003556 assay Methods 0.000 title 1
- 239000000090 biomarker Substances 0.000 title 1
- 208000029028 brain injury Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4727—Calcium binding proteins, e.g. calmodulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70525—ICAM molecules, e.g. CD50, CD54, CD102
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/825—Metallothioneins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/988—Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361847213P | 2013-07-17 | 2013-07-17 | |
| PCT/US2014/046986 WO2015009907A1 (en) | 2013-07-17 | 2014-07-17 | A multi-protein biomarker assay for brain injury detection and outcome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL243393A0 true IL243393A0 (en) | 2016-03-31 |
Family
ID=52346714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL243393A IL243393A0 (en) | 2013-07-17 | 2015-12-28 | Testing by a multi-protein biomarker for the detection and results of brain injury |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US10534003B2 (enExample) |
| EP (2) | EP3022322A4 (enExample) |
| JP (3) | JP6611710B2 (enExample) |
| IL (1) | IL243393A0 (enExample) |
| WO (1) | WO2015009907A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12172017B2 (en) * | 2011-05-09 | 2024-12-24 | Setpoint Medical Corporation | Vagus nerve stimulation to treat neurodegenerative disorders |
| US9709573B2 (en) * | 2012-03-13 | 2017-07-18 | The Johns Hopkins University | Citrullinated brain and neurological proteins as biomarkers of brain injury or neurodegeneration |
| EP3022322A4 (en) | 2013-07-17 | 2017-05-17 | The Johns Hopkins University | A multi-protein biomarker assay for brain injury detection and outcome |
| US11311725B2 (en) | 2014-10-24 | 2022-04-26 | Setpoint Medical Corporation | Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation |
| EP3254106A4 (en) | 2015-02-05 | 2018-10-03 | Immunarray USA, Inc. | Methods and compositions for diagnosing brain injury or neurodegeneration |
| US10667737B2 (en) | 2015-03-23 | 2020-06-02 | International Business Machines Corporation | Monitoring a person for indications of a brain injury |
| FI20155280A7 (fi) | 2015-04-15 | 2016-10-16 | Medicortex Finland Oy | Aivovamman prognostisia ja diagnostisia glykaanipohjaisia biomarkkereita |
| US10244971B2 (en) * | 2015-05-12 | 2019-04-02 | International Business Machines Corporation | Mouthguard for analysis of biomarkers for traumatic brain injury |
| US11471681B2 (en) | 2016-01-20 | 2022-10-18 | Setpoint Medical Corporation | Batteryless implantable microstimulators |
| WO2017127756A1 (en) | 2016-01-20 | 2017-07-27 | Setpoint Medical Corporation | Control of vagal stimulation |
| US10583304B2 (en) | 2016-01-25 | 2020-03-10 | Setpoint Medical Corporation | Implantable neurostimulator having power control and thermal regulation and methods of use |
| US20180106818A1 (en) * | 2016-10-03 | 2018-04-19 | Abbott Laboratories | Methods of assessing gfap status in patient samples |
| US12020820B1 (en) | 2017-03-03 | 2024-06-25 | Cerner Innovation, Inc. | Predicting sphingolipidoses (fabry's disease) and decision support |
| US11335461B1 (en) * | 2017-03-06 | 2022-05-17 | Cerner Innovation, Inc. | Predicting glycogen storage diseases (Pompe disease) and decision support |
| WO2018175942A1 (en) | 2017-03-23 | 2018-09-27 | Abbott Laboratories | Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1 |
| EP3610268B1 (en) | 2017-04-15 | 2025-09-24 | Abbott Laboratories | Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers |
| BR112019022476A2 (pt) | 2017-04-28 | 2020-05-12 | Abbott Laboratories | Métodos para o auxílio no diagnóstico e determinação hiperagudos de lesão cerebral traumática usando biomarcadores iniciais em pelo menos duas amostras a partir do mesmo ser humano |
| US11709168B2 (en) | 2017-05-23 | 2023-07-25 | Brainbox Solutions, Inc. | Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma |
| WO2018218169A1 (en) * | 2017-05-25 | 2018-11-29 | Abbott Laboratories | Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers |
| CA3059607A1 (en) | 2017-05-30 | 2018-12-06 | Abbott Laboratories | Methods for aiding in diagnosing and evaluating a mild traumatic brain injury in a human subject using cardiac troponin i |
| JP7454945B2 (ja) | 2017-07-03 | 2024-03-25 | アボット・ラボラトリーズ | 血液中のユビキチンカルボキシ末端ヒドロラーゼｌ１レベルを測定するための、改善された方法 |
| KR102690820B1 (ko) * | 2017-07-14 | 2024-08-02 | 가부시키가이샤 엠씨비아이 | 질환 검출 방법 |
| EP3668402B1 (en) | 2017-08-14 | 2024-07-31 | Setpoint Medical Corporation | Vagus nerve stimulation pre-screening test |
| KR102633621B1 (ko) * | 2017-09-01 | 2024-02-05 | 벤 바이오사이언시스 코포레이션 | 진단 및 치료 모니터링용 바이오마커로서의 당펩티드의 식별 및 용도 |
| US11923048B1 (en) | 2017-10-03 | 2024-03-05 | Cerner Innovation, Inc. | Determining mucopolysaccharidoses and decision support tool |
| CA3067055A1 (en) | 2017-12-09 | 2019-06-13 | Abbott Laboratories | Methods for aiding in diagnosing and evaluating a traumatic brain injury in a human subject using a combination of gfap and uch-l1 |
| BR112019028254A2 (pt) | 2017-12-09 | 2020-07-14 | Abbott Laboratories | métodos para ajudar no diagnóstico e avaliação de um paciente que sofreu uma lesão ortopédica e que sofreu ou pode ter sofrido uma lesão na cabeça, tal como uma lesão cerebral traumática (lct) leve, usando a proteína ácida fibrilar glial (gfap) e/ou a hidrolase carbóxi-terminal da ubiquitina l1 (uch-l1) |
| EP3732489B1 (en) * | 2017-12-29 | 2025-10-22 | Abbott Laboratories | Novel biomarkers and methods for diagnosing and evaluating traumatic brain injury |
| WO2020006445A1 (en) | 2018-06-29 | 2020-01-02 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Biomarkers and treatment methods for traumatic brain injury associated impairments |
| US11260229B2 (en) | 2018-09-25 | 2022-03-01 | The Feinstein Institutes For Medical Research | Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation |
| CA3128367A1 (en) * | 2019-02-01 | 2020-08-06 | Venn Biosciences Corporation | Biomarkers for diagnosing ovarian cancer |
| EP3952982B1 (en) | 2019-04-12 | 2024-03-27 | Setpoint Medical Corporation | Vagus nerve stimulation system to treat neurodegenerative disorders |
| WO2020223462A1 (en) * | 2019-04-30 | 2020-11-05 | University Of Florida Research Foundation, Inc. | Biomarker panel for sepsis encephalopathy |
| KR102464243B1 (ko) * | 2020-04-01 | 2022-11-08 | 프리시젼바이오 주식회사 | 외상성 뇌손상 바이오마커 검출용 시분해 형광분석 측방유동 분석장치 및 이를 이용한 외상성 뇌손상 바이오마커 측정방법 |
| US11938324B2 (en) | 2020-05-21 | 2024-03-26 | The Feinstein Institutes For Medical Research | Systems and methods for vagus nerve stimulation |
| EP3982123A1 (en) * | 2020-10-08 | 2022-04-13 | Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca | Markers and their use in brain injury |
| KR102189144B1 (ko) * | 2020-10-15 | 2020-12-09 | 서울대학교병원 | 만성신장질환 악화 예측 마커 및 이를 이용한 악화 예측 방법 |
| US12444497B2 (en) | 2021-05-17 | 2025-10-14 | Setpoint Medical Corporation | Neurostimulation parameter authentication and expiration system for neurostimulation |
| FI130340B (en) * | 2022-02-22 | 2023-06-29 | Medicortex Finland Oy | Procedure for the diagnosis of traumatic brain injury |
| CN114594273B (zh) * | 2022-05-09 | 2024-02-27 | 上海众启生物科技有限公司 | 一种脑梗塞生物标记物及其应用 |
| CA3258179A1 (en) * | 2022-06-05 | 2023-12-14 | Sportgait Inc | HEALTHCARE SYSTEM AND METHODS FOR MANAGING BRAIN INJURIES OR COMMOTIONS |
| JP7489723B2 (ja) | 2022-10-05 | 2024-05-24 | 和哉 松尾 | プログラム、情報処理装置、情報処理方法、および学習モデルの生成方法 |
| WO2025188805A1 (en) * | 2024-03-04 | 2025-09-12 | University Of Denver | Blood based rapid diagnostic system for brain hemorrhage detection and associated methods |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4981785A (en) | 1988-06-06 | 1991-01-01 | Ventrex Laboratories, Inc. | Apparatus and method for performing immunoassays |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5270163A (en) | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
| US5683867A (en) | 1990-06-11 | 1997-11-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: blended SELEX |
| US5567588A (en) | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
| US5496938A (en) | 1990-06-11 | 1996-03-05 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to HIV-RT and HIV-1 rev |
| ATE160821T1 (de) | 1990-06-11 | 1997-12-15 | Nexstar Pharmaceuticals Inc | Nukleinsäureliganden |
| US5637459A (en) | 1990-06-11 | 1997-06-10 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chimeric selex |
| US5660985A (en) | 1990-06-11 | 1997-08-26 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands containing modified nucleotides |
| US5707796A (en) | 1990-06-11 | 1998-01-13 | Nexstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
| US6011020A (en) | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
| US5376313A (en) | 1992-03-27 | 1994-12-27 | Abbott Laboratories | Injection molding a plastic assay cuvette having low birefringence |
| NZ267842A (en) | 1993-05-28 | 1997-09-22 | Baylor College Medicine | Apparatus for measuring molecular mass (by mass spectrometry) in which the sample is ionised on the sample holder and desorbed therefrom by laser pulses |
| US5866434A (en) | 1994-12-08 | 1999-02-02 | Meso Scale Technology | Graphitic nanotubes in luminescence assays |
| US6207369B1 (en) | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6140045A (en) | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| BR9607193B1 (pt) | 1995-03-10 | 2009-01-13 | teste de eletroquimioluscÊncia multi-especÍfico de méltiplos conjuntos. | |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| JP2000502450A (ja) | 1995-12-22 | 2000-02-29 | アボツト・ラボラトリーズ | 蛍光偏光免疫アッセイによる診断法 |
| US5885529A (en) | 1996-06-28 | 1999-03-23 | Dpc Cirrus, Inc. | Automated immunoassay analyzer |
| NZ516848A (en) | 1997-06-20 | 2004-03-26 | Ciphergen Biosystems Inc | Retentate chromatography apparatus with applications in biology and medicine |
| US6413783B1 (en) | 1997-09-18 | 2002-07-02 | Meso Scale Technologies, Llc | Assay sonication apparatus and methodology |
| CA2323638A1 (en) | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6780606B1 (en) | 1999-02-26 | 2004-08-24 | Synx Pharma, Inc. | Method for diagnosing and distinguishing stroke and diagnostic devices for use therein |
| WO2000056934A1 (en) | 1999-03-24 | 2000-09-28 | Packard Bioscience Company | Continuous porous matrix arrays |
| EP1236173A2 (en) | 1999-10-27 | 2002-09-04 | Biowulf Technologies, LLC | Methods and devices for identifying patterns in biological systems |
| SG144731A1 (en) | 2000-07-18 | 2008-08-28 | Correlogic Systems Inc | A process for discriminating between biological states based on hidden patterns from biological data |
| AU2001291217A1 (en) | 2000-09-22 | 2002-04-02 | University Of Aarhus | Novel compositions and methods for lymphoma and leukemia |
| US20020164576A1 (en) | 2000-09-22 | 2002-11-07 | Pedersen Finn Skou | Methods for diagnosis and treatment of diseases associated with altered expression of Nrf2 |
| AU2002241535B2 (en) | 2000-11-16 | 2006-05-18 | Ciphergen Biosystems, Inc. | Method for analyzing mass spectra |
| US7113896B2 (en) | 2001-05-11 | 2006-09-26 | Zhen Zhang | System and methods for processing biological expression data |
| US7144708B2 (en) | 2001-06-25 | 2006-12-05 | The Cleveland Clinic Foundation | Markers of blood barrier disruption and methods of using same |
| US6884591B2 (en) | 2001-06-25 | 2005-04-26 | The Cleveland Clinic Foundation | Peripheral marker of blood brain barrier permeability |
| CA2451789C (en) | 2001-06-29 | 2012-03-27 | Meso Scale Technologies, Llc. | Assay plates, reader systems and methods for luminescence test measurements |
| WO2003068947A1 (en) | 2001-07-30 | 2003-08-21 | Meso Scale Technologies, Llc. | Assay electrodes having immobilized lipid/protein layers and methods of making and using the same |
| CA2457775A1 (en) | 2001-08-20 | 2003-02-27 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
| WO2003022028A2 (en) | 2001-09-10 | 2003-03-20 | Meso Scale Technologies, Llc | Methods, reagents, kits and apparatus for protein function analysis |
| CA3081228C (en) | 2001-09-10 | 2022-02-15 | Meso Scale Technologies, Llc | Assay buffer, compositions containing the same, and methods of using the same |
| US20070098728A1 (en) | 2001-09-24 | 2007-05-03 | Pedersen Finn S | Novel compositions and methods in cancer |
| WO2003048768A2 (en) | 2001-12-05 | 2003-06-12 | Sense Proteomic Limited | Protein arrays for allelic variants and uses thereof |
| KR20040081749A (ko) * | 2002-01-14 | 2004-09-22 | 헨리 포드 헬쓰 시스템 | 혈관을 형성하고 혈관신생 및 영양 인자를 생성시키는데사용하기 위한 골수 기질 세포로부터의 물질 |
| US20020193950A1 (en) | 2002-02-25 | 2002-12-19 | Gavin Edward J. | Method for analyzing mass spectra |
| US7036946B1 (en) | 2002-09-13 | 2006-05-02 | Rockwell Collins, Inc. | LCD backlight with UV light-emitting diodes and planar reactive element |
| AU2003302340B8 (en) * | 2002-12-24 | 2008-09-11 | Biosite Incorporated | Markers for differential diagnosis and methods of use thereof |
| AU2003302263A1 (en) | 2002-12-26 | 2004-07-29 | Meso Scale Technologies, Llc. | Assay cartridges and methods of using the same |
| EP1519194A1 (en) | 2003-09-24 | 2005-03-30 | Roche Diagnostics GmbH | Use of gfap for identification of intracerebral hemorrhage |
| US7981362B2 (en) | 2003-11-04 | 2011-07-19 | Meso Scale Technologies, Llc | Modular assay plates, reader systems and methods for test measurements |
| US8492107B2 (en) | 2004-04-15 | 2013-07-23 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for nervous system injury and other neural disorders |
| US20140303041A1 (en) | 2004-04-15 | 2014-10-09 | University Of Florida Research Foundation Inc. | In vitro diagnostic devices for nervous system injury and other neural disorders |
| ES2367311T3 (es) | 2004-04-15 | 2011-11-02 | University Of Florida Research Foundation, Inc. | Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales. |
| EP1745149A4 (en) | 2004-04-15 | 2008-08-06 | Univ Florida | NEURALE PROTEINS AS BIOMARKERS FOR INJURY TO THE NERVOUS SYSTEM AND OTHER NEURAL DISORDERS |
| WO2005121798A1 (en) | 2004-06-03 | 2005-12-22 | Meso Scale Technologies, Llc | Methods and apparatuses for conducting assays |
| WO2006012351A2 (en) | 2004-06-25 | 2006-02-02 | Washington University | Markers for brain damage |
| US20060257943A1 (en) | 2005-01-25 | 2006-11-16 | Cis Biotech, Inc. | Ischemic biomarkers and their use to predict adverse neurological events from surgery |
| US7884260B2 (en) | 2005-06-14 | 2011-02-08 | University Of Chicago | Cell-based screen for agents useful for reducing neuronal demyelination or promoting neuronal remyelination |
| GB2428240A (en) | 2005-07-14 | 2007-01-24 | Univ Gen Ve | Diagnostic method for brain damage-related disorders |
| WO2007123976A2 (en) | 2006-04-18 | 2007-11-01 | The Board Of Trustees Of The Leland Stanford Junior University | Antibody profiling for determination of patient responsiveness |
| WO2007136617A2 (en) | 2006-05-18 | 2007-11-29 | Walter Reed Army Institute Of Research (Wrair) | Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury |
| US8088584B2 (en) | 2006-10-16 | 2012-01-03 | Bayer Schering Pharma Aktiengesellschaft | LTBP2 as a biomarker and diagnostic target |
| JP5240945B2 (ja) | 2006-11-28 | 2013-07-17 | ピクター リミテッド | アッセイ膜およびその使用法 |
| WO2008097618A1 (en) | 2007-02-06 | 2008-08-14 | University Of Florida Research Foundation, Inc. | Synaptotagmin and collapsin response mediator protein as biomarkers for traumatic brain injury |
| EP2015196A1 (en) | 2007-06-28 | 2009-01-14 | Siemens Aktiengesellschaft | Programmer interface for manufacturing execution system |
| JP2011511301A (ja) | 2008-02-04 | 2011-04-07 | バンヤン・バイオマーカーズ・インコーポレイテッド | 脳損傷を診断または治療するための方法 |
| US8497078B2 (en) | 2008-05-23 | 2013-07-30 | The Johns Hopkins University | Biomarkers for myocardial ischemia |
| EP2143735A1 (en) | 2008-07-10 | 2010-01-13 | Institut Pasteur | Variable domains of camelid heavy-chain antibodies directed against glial fibrillary acidic proteins |
| WO2010017515A2 (en) | 2008-08-08 | 2010-02-11 | Integrated Diagnostics Inc. | Breast cancer specific markers and methods of use |
| WO2010019553A2 (en) * | 2008-08-11 | 2010-02-18 | Banyan Biomarkers, Inc. | Biomarker detection process and assay of neurological condition |
| US20140342381A1 (en) | 2008-08-11 | 2014-11-20 | Banyan Biomarkers, Inc. | Devices and methods for biomarker detection process and assay of neurological condition |
| CA2766057A1 (en) * | 2009-06-19 | 2010-12-23 | Banyan Biomarkers, Inc. | Biomarker assay of neurological condition |
| US20170315136A9 (en) | 2009-06-19 | 2017-11-02 | Banyan Biomarkers, Inc. | Biomarker assay of neurological condition |
| AU2010291933B2 (en) | 2009-09-14 | 2016-09-08 | Banyan Biomarkers, Inc. | Micro-RNA, autoantibody and protein markers for diagnosis of neuronal injury |
| GB201008541D0 (en) | 2010-05-21 | 2010-07-07 | Univ Geneve | Diagnostic methods |
| WO2012051519A2 (en) * | 2010-10-14 | 2012-04-19 | The Johns Hopkins University | Biomarkers of brain injury |
| MX2013008746A (es) | 2011-01-28 | 2014-06-23 | Immunosciences Lab Inc | Metodo para la deteccion de permeabilidad intestinal y de la barrera hemato-encefalica y materiales de prueba para este. |
| WO2012155134A2 (en) | 2011-05-12 | 2012-11-15 | The Johns Hopkins University | Assay reagents for a neurogranin diagnostic kit |
| WO2012170998A1 (en) | 2011-06-10 | 2012-12-13 | Cornell University | Immobilized protein system for rapid and enhanced multiplexed diagnostics |
| WO2013173596A1 (en) | 2012-05-16 | 2013-11-21 | Trustees Of Boston University | Chronic traumatic encephalopathy in blast-exposed individuals |
| WO2014194329A1 (en) | 2013-05-31 | 2014-12-04 | Banyan Biomarkers, Inc. | NEURAL SPECIFIC S100β FOR BIOMARKER ASSAYS AND DEVICES FOR DETECTION OF A NEUROLOGICAL CONDITION |
| EP3022322A4 (en) | 2013-07-17 | 2017-05-17 | The Johns Hopkins University | A multi-protein biomarker assay for brain injury detection and outcome |
| WO2015066211A1 (en) | 2013-10-29 | 2015-05-07 | Banyan Biomarkers, Inc. | Uch-l1 isoforms, assays and devices for detection of a neurological condition |
-
2014
- 2014-07-17 EP EP14826786.7A patent/EP3022322A4/en not_active Ceased
- 2014-07-17 JP JP2016527092A patent/JP6611710B2/ja active Active
- 2014-07-17 WO PCT/US2014/046986 patent/WO2015009907A1/en not_active Ceased
- 2014-07-17 EP EP20191259.9A patent/EP3757226A3/en active Pending
- 2014-07-17 US US14/905,312 patent/US10534003B2/en active Active
-
2015
- 2015-12-28 IL IL243393A patent/IL243393A0/en unknown
-
2019
- 2019-10-29 JP JP2019195925A patent/JP6980291B2/ja active Active
- 2019-12-13 US US16/713,425 patent/US11499982B2/en active Active
-
2021
- 2021-11-08 JP JP2021181686A patent/JP2022023999A/ja active Pending
-
2022
- 2022-11-08 US US17/982,769 patent/US12339288B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20230077876A1 (en) | 2023-03-16 |
| WO2015009907A1 (en) | 2015-01-22 |
| EP3022322A4 (en) | 2017-05-17 |
| EP3757226A2 (en) | 2020-12-30 |
| JP2020034567A (ja) | 2020-03-05 |
| JP6980291B2 (ja) | 2021-12-15 |
| EP3757226A3 (en) | 2021-05-05 |
| US20160178643A1 (en) | 2016-06-23 |
| US10534003B2 (en) | 2020-01-14 |
| US11499982B2 (en) | 2022-11-15 |
| US20200116739A1 (en) | 2020-04-16 |
| JP6611710B2 (ja) | 2019-11-27 |
| EP3022322A1 (en) | 2016-05-25 |
| US12339288B2 (en) | 2025-06-24 |
| JP2022023999A (ja) | 2022-02-08 |
| JP2016533499A (ja) | 2016-10-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL243393A0 (en) | Testing by a multi-protein biomarker for the detection and results of brain injury | |
| EP2967395A4 (en) | WINDOW TECHNOLOGY FOR IDENTIFICATION OF IMPACT RESULTS | |
| LU91942B1 (en) | Capacitive detection device | |
| LU92179B1 (en) | Capacitive sensing device | |
| ZA201509201B (en) | Soybean transgenic event mon87751 and methods for detection and use thereof | |
| GB201318824D0 (en) | Tyre condition analysis | |
| ZA201504861B (en) | Apparatus for improved disease detection | |
| DK3011059T3 (da) | Biomarkør-identifikation | |
| EP2971183A4 (en) | IMPROVED TEST PROCEDURES | |
| LU92178B1 (en) | Capacitive sensing device | |
| EP2977754A4 (en) | DEVICE FOR DETECTING MAGNETIC CHARACTERISTICS | |
| GB2511803B (en) | Pneumatic sensing apparatus | |
| EP3037841A4 (en) | OBJECT DETECTION DEVICE FOR A VEHICLE | |
| GB201321430D0 (en) | Assay device | |
| PL2767964T3 (pl) | Urządzenie do pomiaru pojazdu | |
| GB201306792D0 (en) | PIIINP Neo-epitope assay | |
| SG11201601805UA (en) | A Device For Detecting A Spike In One Of A Plurality Of Neural Signals | |
| IL240319A (en) | Quick discovery | |
| EP2960621A4 (en) | SHAPE INSPECTION DEVICE | |
| PL2948930T3 (pl) | Unikalna identyfikacja monety | |
| SG10201405620RA (en) | Stall condition detection | |
| GB201309701D0 (en) | Transponder key testing device | |
| EP2963530A4 (en) | OPERATION DETECTION DEVICE | |
| GB201303090D0 (en) | Sensing device | |
| GB201321843D0 (en) | Identification device |