IL234937B - Improved booster system for oral administration of vaccine - Google Patents

Improved booster system for oral administration of vaccine

Info

Publication number
IL234937B
IL234937B IL234937A IL23493714A IL234937B IL 234937 B IL234937 B IL 234937B IL 234937 A IL234937 A IL 234937A IL 23493714 A IL23493714 A IL 23493714A IL 234937 B IL234937 B IL 234937B
Authority
IL
Israel
Prior art keywords
adminstration
adjuvant system
oral vaccine
improved adjuvant
improved
Prior art date
Application number
IL234937A
Other languages
English (en)
Hebrew (he)
Other versions
IL234937A0 (en
Original Assignee
Vaxform Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxform Llc filed Critical Vaxform Llc
Publication of IL234937A0 publication Critical patent/IL234937A0/en
Publication of IL234937B publication Critical patent/IL234937B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
IL234937A 2012-04-04 2014-10-02 Improved booster system for oral administration of vaccine IL234937B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261686372P 2012-04-04 2012-04-04
PCT/US2013/000102 WO2013151595A1 (en) 2012-04-04 2013-04-03 Improved adjuvant system for oral vaccine adminstration

Publications (2)

Publication Number Publication Date
IL234937A0 IL234937A0 (en) 2014-12-31
IL234937B true IL234937B (en) 2021-10-31

Family

ID=49300897

Family Applications (1)

Application Number Title Priority Date Filing Date
IL234937A IL234937B (en) 2012-04-04 2014-10-02 Improved booster system for oral administration of vaccine

Country Status (10)

Country Link
US (3) US20150079130A1 (enExample)
EP (2) EP3549605A1 (enExample)
JP (1) JP6240155B2 (enExample)
KR (1) KR101867428B1 (enExample)
AU (1) AU2013243971B2 (enExample)
CA (1) CA2903313C (enExample)
DK (1) DK2833914T3 (enExample)
IL (1) IL234937B (enExample)
MX (1) MX364946B (enExample)
WO (1) WO2013151595A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2939581C (en) * 2014-02-20 2024-01-23 Vaxart, Inc. Formulations for small intestinal delivery
WO2015192216A1 (en) * 2014-06-20 2015-12-23 University Of Saskatchewan Exotoxin/thermolysin compositions and methods and uses for treating or preventing laminitis
ES2832504T3 (es) 2015-06-12 2021-06-10 Vaxart Inc Formulaciones para administración de antígenos de norovirus y rsv en el intestino delgado
BE1024210B1 (fr) * 2016-03-07 2017-12-18 Glaxosmithkline Biologicals Sa Particules pour l'administration de medicaments
BR112020021134A2 (pt) * 2018-04-16 2021-03-23 Merck Patent Gmbh aditivos para formulações de proteínas para aprimorar estabilidade térmica
KR102369740B1 (ko) 2020-09-21 2022-03-02 부경대학교 산학협력단 자궁경부암 조기진단을 위한 모바일 질확대경 장치
WO2022094816A1 (en) * 2020-11-04 2022-05-12 Janssen Pharmaceuticals, Inc. Solid formulation
CN113750228B (zh) * 2021-09-25 2024-02-20 大连理工大学 一种冷冻保护剂在铝佐剂中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4133397A (en) * 1996-10-28 1998-05-22 Pfizer Inc. Oral vaccines for young animals with an enteric coating
AU722326B2 (en) * 1997-02-14 2000-07-27 Merck & Co., Inc. Polynucleotide vaccine formulations
US7087235B2 (en) 1997-06-25 2006-08-08 The United States Of America As Represented By The Secretary Of The Army Fusion protein of streptococcal pyrogenic exotoxins
US20030162955A1 (en) * 1998-03-17 2003-08-28 Lionel Chalus Isolated mammalian membrane protein genes; related reagents
DE69930509T2 (de) * 1998-07-08 2006-11-30 Kirin-Amgen Inc., Wilmington Pulverförmiges präparat zur anwendung auf schleimhäuten welches ein polymeres arzneimittel enthält
EP1046651A1 (en) * 1999-04-19 2000-10-25 Koninklijke Universiteit Nijmegen Composition and method for modulating dendritic cell-T interaction
AP2005003234A0 (en) * 2002-08-20 2005-03-31 Genitrix Llc Lectin compositions and methods for modulating an immune response to an antigen.
US20040213745A1 (en) * 2003-02-20 2004-10-28 Vincent Sullivan Powder formulations of rSEB for improved vaccination
GB0505518D0 (en) * 2005-03-17 2005-04-27 Chiron Srl Combination vaccines with whole cell pertussis antigen
WO2008039432A1 (en) * 2006-09-26 2008-04-03 Alexion Pharmaceuticals, Inc. Compositions and methods for enhancing an adjuvant
CN102573802A (zh) * 2009-08-12 2012-07-11 希格默伊德药业有限公司 包含聚合物基质和油相的免疫调节组合物
GB0919690D0 (en) * 2009-11-10 2009-12-23 Guy S And St Thomas S Nhs Foun compositions for immunising against staphylococcus aureus
GB201101665D0 (en) * 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions

Also Published As

Publication number Publication date
IL234937A0 (en) 2014-12-31
MX364946B (es) 2019-05-15
EP2833914B1 (en) 2019-01-16
EP2833914A4 (en) 2016-03-30
WO2013151595A1 (en) 2013-10-10
DK2833914T3 (en) 2019-03-11
EP3549605A1 (en) 2019-10-09
AU2013243971A1 (en) 2014-10-02
US20210052725A1 (en) 2021-02-25
KR20150002755A (ko) 2015-01-07
EP2833914A1 (en) 2015-02-11
CA2903313C (en) 2019-10-22
US20150079130A1 (en) 2015-03-19
KR101867428B1 (ko) 2018-07-19
JP6240155B2 (ja) 2017-11-29
JP2015512441A (ja) 2015-04-27
CA2903313A1 (en) 2013-10-10
MX2014011806A (es) 2015-06-03
US20190105389A1 (en) 2019-04-11
AU2013243971B2 (en) 2017-01-05

Similar Documents

Publication Publication Date Title
IL223206A0 (en) Vaccine formulations
IL235890A0 (en) vaccine
IL234937B (en) Improved booster system for oral administration of vaccine
GB201223386D0 (en) Vaccine
PL2755680T3 (pl) Preparaty szczepionkowe w postaci cząstek
IL231043A0 (en) vaccine
GB201119999D0 (en) Vaccine
GB201014965D0 (en) Vaccine
ZA201402071B (en) Vaccine therapy
EP2929894A4 (en) VACCINE ADJUVANS, PREPARATION AND VACCINES THEREOF
EP2929893A4 (en) ADJUVANS FOR SLEEPING VACCINE
GB201013006D0 (en) Vaccine
GB201006324D0 (en) Vaccine
GB201120000D0 (en) Vaccine
GB201210226D0 (en) Vaccine
GB201202090D0 (en) Vaccine
EP2621530A4 (en) IMPROVED ADJUVANT SYSTEM FOR VACCINE DELIVERY
ZA201302154B (en) Vaccine
GB2515669B (en) Bacterial vaccine
GB201108256D0 (en) Vaccine
GB201121647D0 (en) Vaccine
GB201007589D0 (en) Vaccine
GB201012283D0 (en) Vaccine
GB201007588D0 (en) Vaccine
GB201217321D0 (en) Vaccine