IL227890A0 - Antiaging compounds containing bile acid and fatty acid conjugates - Google Patents
Antiaging compounds containing bile acid and fatty acid conjugatesInfo
- Publication number
- IL227890A0 IL227890A0 IL227890A IL22789013A IL227890A0 IL 227890 A0 IL227890 A0 IL 227890A0 IL 227890 A IL227890 A IL 227890A IL 22789013 A IL22789013 A IL 22789013A IL 227890 A0 IL227890 A0 IL 227890A0
- Authority
- IL
- Israel
- Prior art keywords
- fatty acid
- aging compositions
- conjugates
- bile acid
- bile
- Prior art date
Links
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 title 1
- 230000003712 anti-aging effect Effects 0.000 title 1
- 239000003613 bile acid Substances 0.000 title 1
- 235000014113 dietary fatty acids Nutrition 0.000 title 1
- 229930195729 fatty acid Natural products 0.000 title 1
- 239000000194 fatty acid Substances 0.000 title 1
- 150000004665 fatty acids Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL227890A IL227890A0 (en) | 2013-08-08 | 2013-08-08 | Antiaging compounds containing bile acid and fatty acid conjugates |
| JP2016532791A JP2016527306A (ja) | 2013-08-08 | 2014-08-07 | 胆汁酸−脂肪酸抱合体を含む抗老化組成物 |
| US14/910,477 US20160175223A1 (en) | 2013-08-08 | 2014-08-07 | Anti-aging compositions comprising bile acid-fatty acid conjugates |
| CA2920456A CA2920456A1 (en) | 2013-08-08 | 2014-08-07 | Anti-aging compositions comprising bile acid-fatty acid conjugates |
| CN201480055618.6A CN105611910A (zh) | 2013-08-08 | 2014-08-07 | 包含胆汁酸-脂肪酸缀合物的抗老化组合物 |
| EP14834924.4A EP3030221A4 (en) | 2013-08-08 | 2014-08-07 | Anti-aging compositions comprising bile acid-fatty acid conjugates |
| PCT/IL2014/050717 WO2015019358A1 (en) | 2013-08-08 | 2014-08-07 | Anti-aging compositions comprising bile acid-fatty acid conjugates |
| HK16112516.2A HK1224198A1 (zh) | 2013-08-08 | 2014-08-07 | 包含胆汁酸- 脂肪酸缀合物的抗老化组合物 |
| AU2014304078A AU2014304078A1 (en) | 2013-08-08 | 2014-08-07 | Anti-aging compositions comprising bile acid-fatty acid conjugates |
| IL243964A IL243964A0 (en) | 2013-08-08 | 2016-02-04 | Antiaging preparations containing bile acid and fatty acid conjugates |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL227890A IL227890A0 (en) | 2013-08-08 | 2013-08-08 | Antiaging compounds containing bile acid and fatty acid conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL227890A0 true IL227890A0 (en) | 2014-01-30 |
Family
ID=50022996
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL227890A IL227890A0 (en) | 2013-08-08 | 2013-08-08 | Antiaging compounds containing bile acid and fatty acid conjugates |
| IL243964A IL243964A0 (en) | 2013-08-08 | 2016-02-04 | Antiaging preparations containing bile acid and fatty acid conjugates |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL243964A IL243964A0 (en) | 2013-08-08 | 2016-02-04 | Antiaging preparations containing bile acid and fatty acid conjugates |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20160175223A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3030221A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016527306A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105611910A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2014304078A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2920456A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1224198A1 (cg-RX-API-DMAC7.html) |
| IL (2) | IL227890A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015019358A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160175324A1 (en) * | 2013-08-08 | 2016-06-23 | Galderm Therapeutics Ltd. | Anti-acne compositions comprising bile acid-fatty acid conjugates |
| US11571431B2 (en) | 2013-12-04 | 2023-02-07 | Galmed Research And Development Ltd | Aramchol salts |
| WO2016199137A1 (en) | 2015-06-10 | 2016-12-15 | Galmed Research And Development Ltd. | Low dose compositions of aramchol salts |
| US20180000793A1 (en) | 2015-02-06 | 2018-01-04 | Ernesto Abel-Santos | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis |
| IL243707A0 (en) | 2016-01-20 | 2016-05-01 | Galmed Res And Dev Ltd | Treatment to regulate the microbiota in the intestine |
| US11197870B2 (en) | 2016-11-10 | 2021-12-14 | Galmed Research And Development Ltd | Treatment for hepatic fibrosis |
| CN109503693B (zh) * | 2018-12-12 | 2021-04-06 | 合肥工业大学 | 一种利用胆酸为原料合成Aramchol的工艺 |
| JP2021100925A (ja) * | 2019-10-31 | 2021-07-08 | 共栄化学工業株式会社 | 皮膚外用剤 |
| WO2023287261A1 (ko) * | 2021-07-16 | 2023-01-19 | 주식회사 스카이테라퓨틱스 | 담즙산 또는 담즙산 염의 분자 회합체를 포함하는 화장료 조성물 |
| WO2023039159A2 (en) * | 2021-09-09 | 2023-03-16 | Abel Santos Ernesto | Inhibitors of c. difficile spore germination |
| WO2024012317A1 (zh) * | 2022-07-14 | 2024-01-18 | 爱医谷(苏州)生物科技有限公司 | 一种用于抵抗衰老的组合物及其用途或方法 |
| CN116236490A (zh) * | 2023-02-14 | 2023-06-09 | 四川大学 | 脱氧胆酸的用途及药物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4115313A (en) * | 1974-10-08 | 1978-09-19 | Irving Lyon | Bile acid emulsions |
| IL142650A (en) * | 1998-04-08 | 2007-06-03 | Galmed Int Ltd | Use of bile acid conjugates or bile salts and fatty acids or fatty acids in the preparation of pharmaceuticals for lowering cholesterol, for the treatment of fatty liver and for the treatment of hyperglycemia and diabetes |
| US6019992A (en) * | 1998-12-04 | 2000-02-01 | Chesebrough-Pond's Usa Co. | Cosmetic skin care compositions containing 4-chromanone |
| US8975246B2 (en) * | 2001-04-17 | 2015-03-10 | Galmed Research And Development Ltd. | Bile acid or bile salt fatty acid conjugates |
| US20060127468A1 (en) * | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
| ES2296463B1 (es) * | 2005-07-13 | 2009-02-16 | Universidade De Santiago Compostela | Nuevos amidoderivados de acidos billares funcionalizados en la posicion 3 del anillo a. procedimientos para su obtencion y aplicaciones. |
| GB0722077D0 (en) * | 2007-11-09 | 2007-12-19 | Smithkline Beecham Corp | Compounds |
| JP5872158B2 (ja) * | 2008-03-11 | 2016-03-01 | 株式会社 資生堂 | 皮膚美白方法、並びに、皮膚シミ形成抑制及び/又は除去因子のスクリーニング方法 |
| US8937194B2 (en) * | 2008-12-31 | 2015-01-20 | Nitromega Corp. | Topical compositions containing nitro fatty acids |
| WO2010086864A1 (en) * | 2009-02-02 | 2010-08-05 | Galmed International Ltd. | Methods and compositions for treating alzheimer's disease |
| US20160175324A1 (en) * | 2013-08-08 | 2016-06-23 | Galderm Therapeutics Ltd. | Anti-acne compositions comprising bile acid-fatty acid conjugates |
| LT3077047T (lt) * | 2013-12-04 | 2019-08-26 | Galmed Research & Development Ltd. | Aramcholio druskos |
-
2013
- 2013-08-08 IL IL227890A patent/IL227890A0/en unknown
-
2014
- 2014-08-07 US US14/910,477 patent/US20160175223A1/en not_active Abandoned
- 2014-08-07 HK HK16112516.2A patent/HK1224198A1/zh unknown
- 2014-08-07 CA CA2920456A patent/CA2920456A1/en not_active Abandoned
- 2014-08-07 JP JP2016532791A patent/JP2016527306A/ja active Pending
- 2014-08-07 WO PCT/IL2014/050717 patent/WO2015019358A1/en not_active Ceased
- 2014-08-07 CN CN201480055618.6A patent/CN105611910A/zh active Pending
- 2014-08-07 AU AU2014304078A patent/AU2014304078A1/en not_active Abandoned
- 2014-08-07 EP EP14834924.4A patent/EP3030221A4/en not_active Withdrawn
-
2016
- 2016-02-04 IL IL243964A patent/IL243964A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20160175223A1 (en) | 2016-06-23 |
| CA2920456A1 (en) | 2015-02-12 |
| WO2015019358A1 (en) | 2015-02-12 |
| JP2016527306A (ja) | 2016-09-08 |
| CN105611910A (zh) | 2016-05-25 |
| AU2014304078A1 (en) | 2016-02-25 |
| EP3030221A4 (en) | 2017-02-08 |
| HK1224198A1 (zh) | 2017-08-18 |
| IL243964A0 (en) | 2016-04-21 |
| EP3030221A1 (en) | 2016-06-15 |
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