IL218996A - Methods for producing and preserving populations of ectodermal or mesodermal / endodermal origin cells - Google Patents
Methods for producing and preserving populations of ectodermal or mesodermal / endodermal origin cellsInfo
- Publication number
- IL218996A IL218996A IL218996A IL21899612A IL218996A IL 218996 A IL218996 A IL 218996A IL 218996 A IL218996 A IL 218996A IL 21899612 A IL21899612 A IL 21899612A IL 218996 A IL218996 A IL 218996A
- Authority
- IL
- Israel
- Prior art keywords
- ectodermal
- mesodermal
- population
- maintaining
- generating
- Prior art date
Links
- 210000000130 stem cell Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/32—Polylysine, polyornithine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Developmental Biology & Embryology (AREA)
- General Health & Medical Sciences (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Gynecology & Obstetrics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25113009P | 2009-10-13 | 2009-10-13 | |
| US35494710P | 2010-06-15 | 2010-06-15 | |
| PCT/CA2010/001610 WO2011044684A1 (en) | 2009-10-13 | 2010-10-13 | Manipulation of osmolality for differentiating stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL218996A0 IL218996A0 (en) | 2012-06-28 |
| IL218996A true IL218996A (en) | 2017-04-30 |
Family
ID=43855139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL218996A IL218996A (en) | 2009-10-13 | 2012-04-02 | Methods for producing and preserving populations of ectodermal or mesodermal / endodermal origin cells |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10913929B2 (https=) |
| EP (1) | EP2488631B1 (https=) |
| JP (1) | JP5843775B2 (https=) |
| CN (1) | CN102762718B (https=) |
| AU (1) | AU2010306377B2 (https=) |
| IL (1) | IL218996A (https=) |
| WO (1) | WO2011044684A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9708582B2 (en) * | 2009-10-13 | 2017-07-18 | Stemcell Technologies Inc. | Method of differentiating stem cells |
| MY191870A (en) | 2010-06-11 | 2022-07-18 | Regeneron Pharma | Production of fertile xy female animals from xy es cells |
| CN102851314A (zh) * | 2011-07-01 | 2013-01-02 | 中国科学院上海药物研究所 | 诱导性多能干细胞的制备方法和用于制备诱导性多能干细胞的培养基 |
| EP3693455A1 (en) * | 2011-11-04 | 2020-08-12 | Memorial Sloan-Kettering Cancer Center | Midbrain dopamine (da) neurons for engraftment |
| EP2841067A4 (en) * | 2012-04-25 | 2016-04-13 | Univ California | MEDICINAL SCREENING PLATFORM FOR THE RETT SYNDROME |
| WO2014143383A1 (en) | 2013-03-13 | 2014-09-18 | Agilent Technologies, Inc. | Transposome tethered to a gene delivery vehicle |
| ES2806698T3 (es) * | 2013-06-11 | 2021-02-18 | Ncardia B V | Composiciones de medio de cultivo para la maduración de cardiomiocitos derivados de células madre pluripotentes de mamíferos |
| KR102170502B1 (ko) | 2013-12-11 | 2020-10-28 | 리제너론 파마슈티칼스 인코포레이티드 | 게놈의 표적화된 변형을 위한 방법 및 조성물 |
| SI3161128T1 (sl) | 2014-06-26 | 2019-02-28 | Regeneron Pharmaceuticals, Inc. | Postopki in sestavki za ciljano genetsko spremembo in postopki uporabe |
| CN104293730B (zh) * | 2014-09-23 | 2017-07-28 | 云南中科灵长类生物医学重点实验室 | 多能干细胞体外定向分化为心肌细胞的方法 |
| BR112017007770A2 (pt) * | 2014-10-15 | 2018-01-16 | Regeneron Pharma | cultura in vitro, população de hipscs, método para modificar um locus-alvo genômico, e, hipsc. |
| WO2016086092A1 (en) | 2014-11-25 | 2016-06-02 | The Penn State Research Foundation | Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair |
| CN104782583B (zh) * | 2015-04-29 | 2017-04-12 | 中国农业科学院兰州兽医研究所 | 一种棘球蚴体外三维培养模型及其应用 |
| MX388475B (es) | 2015-09-17 | 2025-03-20 | Regeneron Pharma | Selección de células pluripotentes para producir ratones hembra xy fértiles. |
| LT3374509T (lt) * | 2015-11-12 | 2021-03-10 | F. Hoffmann-La Roche Ag | Oligonukleotidai, skirti sukelti iš tėvo paveldėto ube3a raišką |
| CN105886457A (zh) * | 2016-05-16 | 2016-08-24 | 中国人民解放军军事医学科学院野战输血研究所 | 诱导干细胞分化成外胚层祖细胞的方法 |
| US11180733B2 (en) | 2016-07-04 | 2021-11-23 | Agency For Science, Technology And Research | Method of generating mesenchymal stem cells and uses thereof |
| KR101810012B1 (ko) | 2017-10-23 | 2018-01-18 | 차의과학대학교 산학협력단 | 히스톤 데아세틸라제 저해제 및 골 형성 단백질 경로 차단제를 이용한 인간-유래의 체세포로부터 역분화 만능 줄기세포의 제조방법 |
| KR102167257B1 (ko) * | 2019-05-28 | 2020-10-19 | 부산대학교 산학협력단 | 토마티딘 처리를 통한 줄기세포의 성숙화된 심근세포로의 분화유도 촉진 방법 |
| EP4019549B1 (en) | 2019-08-20 | 2025-06-04 | Orizuru Therapeutics, Inc. | Method for enriching cardiac myocytes |
| WO2021145322A1 (ja) * | 2020-01-14 | 2021-07-22 | 味の素株式会社 | 浸透圧低減培地 |
| CA3175071A1 (en) | 2020-03-11 | 2021-09-16 | Bit Bio Limited | Method of generating hepatic cells |
| CN114621920B (zh) * | 2022-02-22 | 2023-09-05 | 中国医学科学院血液病医院(中国医学科学院血液学研究所) | 一种由造血干祖细胞向nk细胞分化的方法及培养基 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5221537A (en) * | 1988-09-02 | 1993-06-22 | Gerald Hecht | Tissue irrigating solutions |
| US7439064B2 (en) | 2000-03-09 | 2008-10-21 | Wicell Research Institute, Inc. | Cultivation of human embryonic stem cells in the absence of feeder cells or without conditioned medium |
| US20020114788A1 (en) * | 2000-07-27 | 2002-08-22 | Ole Isacson | Cell implantation therapy for neurological diseases or disorders |
| US20060040385A1 (en) * | 2002-12-05 | 2006-02-23 | Technion Research & Development Foundation Ltd. | Cultured human pancreatic islets, and uses thereof |
| WO2006019366A1 (en) * | 2003-03-28 | 2006-02-23 | Wisconsin Alumni Research Foundation | Physiochemical culture conditions for embryonic stem cells |
| US8460928B2 (en) | 2005-10-24 | 2013-06-11 | Agency For Science, Technology And Research | Methods of specifying mesodermal, endodermal and mesoendodermal cell fates |
| GB0623635D0 (en) * | 2006-11-27 | 2007-01-03 | Stem Cell Sciences Uk Ltd | Pluripotent cell growth media |
| CA2901105C (en) * | 2007-01-03 | 2018-02-13 | California Stem Cell, Inc. | Stem cell growth media and methods of making and using same |
| EP2115127A4 (en) | 2007-01-17 | 2010-04-07 | Life Technologies Corp | METHOD AND COMPOSITIONS FOR IMPROVING CELL HEALTH IN CULTURES |
| FI20075417A0 (fi) | 2007-06-05 | 2007-06-05 | Marjo-Riitta Suuronen | Koostumuksia ja menetelmiä alkion kantasolujen kasvatukseen |
| AU2009290563A1 (en) | 2008-09-15 | 2010-03-18 | Genentech, Inc. | Compositions and methods for regulating cell osmolarity |
-
2010
- 2010-10-13 JP JP2012533443A patent/JP5843775B2/ja active Active
- 2010-10-13 CN CN201080056644.2A patent/CN102762718B/zh active Active
- 2010-10-13 US US12/903,521 patent/US10913929B2/en active Active
- 2010-10-13 EP EP10822954.3A patent/EP2488631B1/en active Active
- 2010-10-13 WO PCT/CA2010/001610 patent/WO2011044684A1/en not_active Ceased
- 2010-10-13 AU AU2010306377A patent/AU2010306377B2/en active Active
-
2012
- 2012-04-02 IL IL218996A patent/IL218996A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP5843775B2 (ja) | 2016-01-13 |
| US10913929B2 (en) | 2021-02-09 |
| CN102762718B (zh) | 2015-06-17 |
| US20110086379A1 (en) | 2011-04-14 |
| EP2488631A1 (en) | 2012-08-22 |
| AU2010306377A1 (en) | 2012-05-10 |
| AU2010306377B2 (en) | 2015-01-22 |
| IL218996A0 (en) | 2012-06-28 |
| JP2013507135A (ja) | 2013-03-04 |
| WO2011044684A1 (en) | 2011-04-21 |
| EP2488631A4 (en) | 2013-06-26 |
| CN102762718A (zh) | 2012-10-31 |
| EP2488631B1 (en) | 2020-01-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed |